Developing New Agents for Treatment of Childhood Cancer: Challenges and Opportunities for Preclinical Testing

por Ghilu, Samson, Kurmasheva, Raushan T., Houghton, Peter J.
Publicado 2021

Preclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and Validation

por Geier, Brian, Kurmashev, Dias, Kurmasheva, Raushan T., Houghton, Peter J.
Publicado 2015

Recent Developments in Nanomedicine for Pediatric Cancer

por Yang, Shicheng, Wallach, Mia, Krishna, Apurva, Kurmasheva, Raushan, Sridhar, Srinivas
Publicado 2021

Nanoformulation of Talazoparib Increases Maximum Tolerated Doses in Combination With Temozolomide for Treatment of Ewing Sarcoma

por Baldwin, Paige, Likhotvorik, Rostislav, Baig, Nabeela, Cropper, Jodie, Carlson, Ruth, Kurmasheva, Raushan, Sridhar, Srinivas
Publicado 2019

Approaches to identifying drug resistance mechanisms to clinically relevant treatments in childhood rhabdomyosarcoma

por Ghilu, Samson, Morton, Christopher L., Vaseva, Angelina V., Zheng, Siyuan, Kurmasheva, Raushan T., Houghton, Peter J.
Publicado 2022

PCAT: an integrated portal for genomic and preclinical testing data of pediatric cancer patient-derived xenograft models

por Yang, Juechen, Li, Qilin, Noureen, Nighat, Fang, Yanbing, Kurmasheva, Raushan, Houghton, Peter J, Wang, Xiaojing, Zheng, Siyuan
Publicado 2020

PEGylated talazoparib enhances therapeutic window of its combination with temozolomide in Ewing sarcoma

por Del Pozo, Vanessa, Robles, Andrew J., Fontaine, Shaun D., Liu, Qianqian, Michalek, Joel E., Houghton, Peter J., Kurmasheva, Raushan T.
Publicado 2021

PARP1-MGMT complex underpins pathway crosstalk in O(6)-methylguanine repair

por Cropper, Jodie D., Alimbetov, Dauren S., Brown, Kevin T. G., Likhotvorik, Rostislav I., Robles, Andrew J., Guerra, James T., He, Boxue, Chen, Yidong, Kwon, Youngho, Kurmasheva, Raushan T.
Publicado 2022

Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma

por Wang, Yifei, Tian, Xiangjun, Zhang, Wendong, Zhang, Zhongting, Lazcano, Rossana, Hingorani, Pooja, Roth, Michael E., Gill, Jonathan D., Harrison, Douglas J., Xu, Zhaohui, Jusu, Sylvester, Kannan, Sankaranarayanan, Wang, Jing, Lazar, Alexander J., Earley, Eric J., Erickson, Stephen W., Gelb, Tara, Huxley, Philip, Lahdenranta, Johanna, Mudd, Gemma, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A., Kolb, Edward A., Gorlick, Richard
Publicado 2022

Genomic profiling of subcutaneous patient-derived xenografts reveals immune constraints on tumor evolution in childhood solid cancer

por He, Funan, Bandyopadhyay, Abhik M., Klesse, Laura J., Rogojina, Anna, Chun, Sang H., Butler, Erin, Hartshorne, Taylor, Holland, Trevor, Garcia, Dawn, Weldon, Korri, Prado, Luz-Nereida Perez, Langevin, Anne-Marie, Grimes, Allison C., Sugalski, Aaron, Shah, Shafqat, Assanasen, Chatchawin, Lai, Zhao, Zou, Yi, Kurmashev, Dias, Xu, Lin, Xie, Yang, Chen, Yidong, Wang, Xiaojing, Tomlinson, Gail E., Skapek, Stephen X., Houghton, Peter J., Kurmasheva, Raushan T., Zheng, Siyuan
Publicado 2023

Comprehensive characterization of patient-derived xenograft models of pediatric leukemia

por Rogojina, Anna, Klesse, Laura J., Butler, Erin, Kim, Jiwoong, Zhang, He, Xiao, Xue, Guo, Lei, Zhou, Qinbo, Hartshorne, Taylor, Garcia, Dawn, Weldon, Korri, Holland, Trevor, Bandyopadhyay, Abhik, Prado, Luz Perez, Wang, Shidan, Yang, Donghan M., Langevan, Anne-Marie, Zou, Yi, Grimes, Allison C., Assanasen, Chatchawin, Gidvani-Diaz, Vinod, Zheng, Siyuan, Lai, Zhao, Chen, Yidong, Xie, Yang, Tomlinson, Gail E., Skapek, Stephen X., Kurmasheva, Raushan T., Houghton, Peter J., Xu, Lin
Publicado 2023

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

por Rokita, Jo Lynne, Rathi, Komal S., Cardenas, Maria F., Upton, Kristen A., Jayaseelan, Joy, Cross, Katherine L., Pfeil, Jacob, Egolf, Laura E., Way, Gregory P., Farrel, Alvin, Kendsersky, Nathan M., Patel, Khushbu, Gaonkar, Krutika S., Modi, Apexa, Berko, Esther R., Lopez, Gonzalo, Vaksman, Zalman, Mayoh, Chelsea, Nance, Jonas, McCoy, Kristyn, Haber, Michelle, Evans, Kathryn, McCalmont, Hannah, Bendak, Katerina, Böhm, Julia W., Marshall, Glenn M., Tyrrell, Vanessa, Kalletla, Karthik, Braun, Frank K., Qi, Lin, Du, Yunchen, Zhang, Huiyuan, Lindsay, Holly B., Zhao, Sibo, Shu, Jack, Baxter, Patricia, Morton, Christopher, Kurmashev, Dias, Zheng, Siyuan, Chen, Yidong, Bowen, Jay, Bryan, Anthony C., Leraas, Kristen M., Coppens, Sara E., Doddapaneni, HarshaVardhan, Momin, Zeineen, Zhang, Wendong, Sacks, Gregory I., Hart, Lori S., Krytska, Kateryna, Mosse, Yael P., Gatto, Gregory J., Sanchez, Yolanda, Greene, Casey S., Diskin, Sharon J., Vaske, Olena Morozova, Haussler, David, Gastier-Foster, Julie M., E. Anders, Kolb, Gorlick, Richard, Li, Xiao-Nan, Reynolds, C. Patrick, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A., Lock, Richard B., Raman, Pichai, Wheeler, David A., Maris, John M.
Publicado 2019