Structural Basis for the Functional Changes by EGFR Exon 20 Insertion Mutations

por Tamirat, Mahlet Z., Kurppa, Kari J., Elenius, Klaus, Johnson, Mark S.
Publicado 2021

ERBB4 Promoter Polymorphism Is Associated with Poor Distant Disease-Free Survival in High-Risk Early Breast Cancer

por Kurppa, Kari J., Rokavec, Matjaz, Sundvall, Maria, Kellokumpu-Lehtinen, Pirkko-Liisa, Joensuu, Heikki, Brauch, Hiltrud, Elenius, Klaus
Publicado 2014

Cell Death or Survival Promoted by Alternative Isoforms of ErbB4

por Sundvall, Maria, Veikkolainen, Ville, Kurppa, Kari, Salah, Zaidoun, Tvorogov, Denis, van Zoelen, E. Joop, Aqeilan, Rami, Elenius, Klaus
Publicado 2010

High frequency of BRAF V600E mutations in ameloblastoma

por Kurppa, Kari J, Catón, Javier, Morgan, Peter R, Ristimäki, Ari, Ruhin, Blandine, Kellokoski, Jari, Elenius, Klaus, Heikinheimo, Kristiina
Publicado 2014

Overexpression of ERBB4 JM-a CYT-1 and CYT-2 isoforms in transgenic mice reveals isoform-specific roles in mammary gland development and carcinogenesis

por Wali, Vikram B, Gilmore-Hebert, Maureen, Mamillapalli, Ramanaiah, Haskins, Jonathan W, Kurppa, Kari J, Elenius, Klaus, Booth, Carmen J, Stern, David F
Publicado 2014

Proteolytic Processing of ErbB4 in Breast Cancer

por Hollmén, Maija, Liu, Ping, Kurppa, Kari, Wildiers, Hans, Reinvall, Irene, Vandorpe, Thijs, Smeets, Ann, Deraedt, Karen, Vahlberg, Tero, Joensuu, Heikki, Leahy, Daniel J., Schöffski, Patrick, Elenius, Klaus
Publicado 2012

TP53 mutations confer resistance to hypomethylating agents and BCL-2 inhibition in myeloid neoplasms

por Schimmer, Roman R., Kovtonyuk, Larisa V., Klemm, Nancy, Fullin, Jonas, Stolz, Sebastian M., Mueller, Jan, Caiado, Francisco, Kurppa, Kari J., Ebert, Benjamin L., Manz, Markus G., Boettcher, Steffen
Publicado 2022

An Unbiased Functional Genetics Screen Identifies Rare Activating ERBB4 Mutations

por Chakroborty, Deepankar, Ojala, Veera K., Knittle, Anna M., Drexler, Jasmin, Tamirat, Mahlet Z., Ruzicka, Regina, Bosch, Karin, Woertl, Johanna, Schmittner, Susanne, Elo, Laura L., Johnson, Mark S., Kurppa, Kari J., Solca, Flavio, Elenius, Klaus
Publicado 2022

Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors

por Kobayashi, Yoshihisa, Oxnard, Geoffrey R., Cohen, Elizabeth F., Mahadevan, Navin R., Alessi, Joao V., Hung, Yin P., Bertram, Arrien A., Heppner, David E., Ribeiro, Mauricio F., Sacardo, Karina P., Saddi, Rodrigo, Macedo, Mariana P., Blasco, Rafael B., Li, Jiaqi, Kurppa, Kari J., Nguyen, Tom, Voligny, Emma, Ananda, Guruprasad, Chiarle, Roberto, Katz, Artur, Tolstorukov, Michael Y., Sholl, Lynette M., Jänne, Pasi A.
Publicado 2022