High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

por Johnston, Michael J., Nikolic, Ana, Ninkovic, Nicoletta, Guilhamon, Paul, Cavalli, Florence M.G., Seaman, Steven, Zemp, Franz J., Lee, John, Abdelkareem, Aly, Ellestad, Katrina, Murison, Alex, Kushida, Michelle M., Coutinho, Fiona J., Ma, Yussanne, Mungall, Andrew J., Moore, Richard, Marra, Marco A., Taylor, Michael D., Dirks, Peter B., Pugh, Trevor J., Morrissy, Sorana, St Croix, Bradley, Mahoney, Douglas J., Lupien, Mathieu, Gallo, Marco
Publicado 2019

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival

por Guilhamon, Paul, Chesnelong, Charles, Kushida, Michelle M, Nikolic, Ana, Singhal, Divya, MacLeod, Graham, Madani Tonekaboni, Seyed Ali, Cavalli, Florence MG, Arlidge, Christopher, Rajakulendran, Nishani, Rastegar, Naghmeh, Hao, Xiaoguang, Hassam, Rozina, Smith, Laura J, Whetstone, Heather, Coutinho, Fiona J, Nadorp, Bettina, Ellestad, Katrina I, Luchman, H Artee, Chan, Jennifer Ai-wen, Shoichet, Molly S, Taylor, Michael D, Haibe-Kains, Benjamin, Weiss, Samuel, Angers, Stephane, Gallo, Marco, Dirks, Peter B, Lupien, Mathieu
Publicado 2021

PRMT5 inhibition disrupts splicing and stemness in glioblastoma

por Sachamitr, Patty, Ho, Jolene C., Ciamponi, Felipe E., Ba-Alawi, Wail, Coutinho, Fiona J., Guilhamon, Paul, Kushida, Michelle M., Cavalli, Florence M. G., Lee, Lilian, Rastegar, Naghmeh, Vu, Victoria, Sánchez-Osuna, María, Coulombe-Huntington, Jasmin, Kanshin, Evgeny, Whetstone, Heather, Durand, Mathieu, Thibault, Philippe, Hart, Kirsten, Mangos, Maria, Veyhl, Joseph, Chen, Wenjun, Tran, Nhat, Duong, Bang-Chi, Aman, Ahmed M., Che, Xinghui, Lan, Xiaoyang, Whitley, Owen, Zaslaver, Olga, Barsyte-Lovejoy, Dalia, Richards, Laura M., Restall, Ian, Caudy, Amy, Röst, Hannes L., Bonday, Zahid Quyoom, Bernstein, Mark, Das, Sunit, Cusimano, Michael D., Spears, Julian, Bader, Gary D., Pugh, Trevor J., Tyers, Mike, Lupien, Mathieu, Haibe-Kains, Benjamin, Artee Luchman, H., Weiss, Samuel, Massirer, Katlin B., Prinos, Panagiotis, Arrowsmith, Cheryl H., Dirks, Peter B.
Publicado 2021