Seven-membered ring nucleobases as inhibitors of human cytidine deaminase and APOBEC3A

por Kurup, Harikrishnan M., Kvach, Maksim V., Harjes, Stefan, Jameson, Geoffrey B., Harjes, Elena, Filichev, Vyacheslav V.
Publicado 2023

Design, Synthesis, and Evaluation of a Cross-Linked Oligonucleotide as the First Nanomolar Inhibitor of APOBEC3A

por Kurup, Harikrishnan M., Kvach, Maksim V., Harjes, Stefan, Barzak, Fareeda M., Jameson, Geoffrey B., Harjes, Elena, Filichev, Vyacheslav V.
Publicado 2022

Small-Angle X-ray Scattering Models of APOBEC3B Catalytic Domain in a Complex with a Single-Stranded DNA Inhibitor

por Barzak, Fareeda M., Ryan, Timothy M., Kvach, Maksim V., Kurup, Harikrishnan M., Aihara, Hideki, Harris, Reuben S., Filichev, Vyacheslav V., Harjes, Elena, Jameson, Geoffrey B.
Publicado 2021

Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity

por Barzak, Fareeda M., Ryan, Timothy M., Mohammadzadeh, Nazanin, Harjes, Stefan, Kvach, Maksim V., Kurup, Harikrishnan M., Krause, Kurt L., Chelico, Linda, Filichev, Vyacheslav V., Harjes, Elena, Jameson, Geoffrey B.
Publicado 2022

Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2′-Deoxyzebularine Analogues

por Kvach, Maksim V., Barzak, Fareeda M., Harjes, Stefan, Schares, Henry A. M., Jameson, Geoffrey B., Ayoub, Alex M., Moorthy, Ramkumar, Aihara, Hideki, Harris, Reuben S., Filichev, Vyacheslav V., Harki, Daniel A., Harjes, Elena
Publicado 2018

Differential Inhibition of APOBEC3 DNA‐Mutator Isozymes by Fluoro‐ and Non‐Fluoro‐Substituted 2′‐Deoxyzebularine Embedded in Single‐Stranded DNA

por Kvach, Maksim V., Barzak, Fareeda M., Harjes, Stefan, Schares, Henry A. M., Kurup, Harikrishnan M., Jones, Katherine F., Sutton, Lorraine, Donahue, John, D'Aquila, Richard T., Jameson, Geoffrey B., Harki, Daniel A., Krause, Kurt L., Harjes, Elena, Filichev, Vyacheslav V.
Publicado 2019