In the field: exploiting the untapped potential of immunogenic modulation by radiation in combination with immunotherapy for the treatment of cancer

por Kwilas, Anna R., Donahue, Renee N., Bernstein, Michael B., Hodge, James W.
Publicado 2012

Dual effects of a targeted small-molecule inhibitor (cabozantinib) on immune-mediated killing of tumor cells and immune tumor microenvironment permissiveness when combined with a c...

por Kwilas, Anna R, Ardiani, Andressa, Donahue, Renee N, Aftab, Dana T, Hodge, James W
Publicado 2014

Androgen deprivation therapy increases the sensitivity of human prostate carcinoma cells to T cell-mediated lysis through an androgen receptor dependent mechanism

por Gameiro, Sofia, Ardiani, Andressa, Kwilas, Anna R, Donahue, Renee N, Hodge, James W
Publicado 2014

Effects of Cabozantinib, a small molecule tyrosine kinase inhibitor, on the immune permissiveness of the tumor microenvironment and immune-mediated killing of tumor cells

por Kwilas, Anna R, Ardiani, Andressa, Donahue, Renee N, Aftab, Dana, Hodge, James W
Publicado 2014

Inhibition of the angiopoietin/Tie2 axis induces immunogenic modulation, which sensitizes human tumor cells to immune attack

por Grenga, Italia, Kwilas, Anna R., Donahue, Renee N., Farsaci, Benedetto, Hodge, James W.
Publicado 2015

Androgen deprivation therapy sensitizes prostate cancer cells to T-cell killing through androgen receptor dependent modulation of the apoptotic pathway

por Ardiani, Andressa, Gameiro, Sofia R., Kwilas, Anna R., Donahue, Renee N., Hodge, James W.
Publicado 2014

A poxviral-based cancer vaccine targeting the transcription factor Twist inhibits primary tumor growth and metastases in a model of metastatic breast cancer and improves survival i...

por Kwilas, Anna R., Ardiani, Andressa, Dirmeier, Ulrike, Wottawah, Cornelia, Schlom, Jeffery, Hodge, James W.
Publicado 2015

Efficient method for site-directed mutagenesis in large plasmids without subcloning

por Hallak, Louay K., Berger, Kelly, Kaspar, Rita, Kwilas, Anna R., Montanaro, Federica, Peeples, Mark E.
Publicado 2017

IL15N72D superagonist/IL15Rα-Fc fusion complex (ALT-803) exhibits anti-metastatic activity in murine breast tumor model

por Kim, Peter S, Kwilas, Anna R, Jeng, Emily K, Wong, Hing C, Schlom, Jeffrey, Hodge, James W
Publicado 2015

Androgen deprivation therapy sensitizes triple negative breast cancer cells to immune-mediated lysis through androgen receptor independent modulation of osteoprotegerin

por Kwilas, Anna R., Ardiani, Andressa, Gameiro, Sofia R., Richards, Jacob, Hall, Ashley B., Hodge, James W.
Publicado 2016

IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-...

por Kim, Peter S., Kwilas, Anna R., Xu, Wenxin, Alter, Sarah, Jeng, Emily K., Wong, Hing C., Schlom, Jeffrey, Hodge, James W.
Publicado 2016

The IDO1 selective inhibitor epacadostat enhances dendritic cell immunogenicity and lytic ability of tumor antigen-specific T cells

por Jochems, Caroline, Fantini, Massimo, Fernando, Romaine I., Kwilas, Anna R., Donahue, Renee N., Lepone, Lauren M., Grenga, Italia, Kim, Young-Seung, Brechbiel, Martin W., Gulley, James L., Madan, Ravi A., Heery, Christopher R., Hodge, James W., Newton, Robert, Schlom, Jeffrey, Tsang, Kwong Y.
Publicado 2016

The generation and analysis of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic

por Tsang, Kwong Y, Gabitzsch, Elizabeth S, Palena, Claudia, David, Justin M, Fantini, Massimo, Kwilas, Anna R, Rice, Adrian E, Latchman, Yvette, Hodge, James W, Jochems, Caroline, Fernando, Romaine I, Gulley, James, Madan, Ravi A, Heery, Christopher R, Balint, Joseph P, Jones, Frank R, Schlom, Jeffrey
Publicado 2015