Humoral immunogenicity of a Coronavirus Disease 2019 (COVID-19) DNA vaccine in rhesus macaques (Macaca mulatta) delivered using needle-free jet injection

por Jay, Alexandra, Kwilas, Steven A., Josleyn, Matthew, Ricks, Keersten, Hooper, Jay W.
Publicado 2023

An attenuated Machupo virus with a disrupted L-segment intergenic region protects guinea pigs against lethal Guanarito virus infection

por Golden, Joseph W., Beitzel, Brett, Ladner, Jason T., Mucker, Eric M., Kwilas, Steven A., Palacios, Gustavo, Hooper, Jay W.
Publicado 2017

Protective efficacy of a SARS-CoV-2 DNA vaccine in wild-type and immunosuppressed Syrian hamsters

por Brocato, Rebecca L., Kwilas, Steven A., Kim, Robert K., Zeng, Xiankun, Principe, Lucia M., Smith, Jeffrey M., Hooper, Jay W.
Publicado 2021

Nanoplasmid Vectors Co-expressing Innate Immune Agonists Enhance DNA Vaccines for Venezuelan Equine Encephalitis Virus and Ebola Virus

por Suschak, John J., Dupuy, Lesley C., Shoemaker, Charles J., Six, Carolyn, Kwilas, Steven A., Spik, Kristin W., Williams, James A., Schmaljohn, Connie S.
Publicado 2020

Three asymptomatic animal infection models of hemorrhagic fever with renal syndrome caused by hantaviruses

por Perley, Casey C., Brocato, Rebecca L., Kwilas, Steven A., Daye, Sharon, Moreau, Alicia, Nichols, Donald K., Wetzel, Kelly S., Shamblin, Joshua, Hooper, Jay W.
Publicado 2019

Adjuvant-enhanced CD4 T Cell Responses are Critical to Durable Vaccine Immunity

por Martins, Karen A.O., Cooper, Christopher L., Stronsky, Sabrina M., Norris, Sarah L.W., Kwilas, Steven A., Steffens, Jesse T., Benko, Jacqueline G., van Tongeren, Sean A., Bavari, Sina
Publicado 2015

Lipid Nanoparticle Formulation Increases Efficiency of DNA-Vectored Vaccines/Immunoprophylaxis in Animals Including Transchromosomic Bovines

por Mucker, Eric M., Karmali, Priya P., Vega, Jerel, Kwilas, Steven A., Wu, Hua, Joselyn, Matthew, Ballantyne, John, Sampey, Darryl, Mukthavaram, Rajesh, Sullivan, Eddie, Chivukula, Pad, Hooper, Jay W.
Publicado 2020

SARS-CoV-2 Doggybone DNA Vaccine Produces Cross-Variant Neutralizing Antibodies and Is Protective in a COVID-19 Animal Model

por Mucker, Eric M., Brocato, Rebecca L., Principe, Lucia M., Kim, Robert K., Zeng, Xiankun, Smith, Jeffrey M., Kwilas, Steven A., Kim, Sungwon, Horton, Helen, Caproni, Lisa, Hooper, Jay W.
Publicado 2022

A DNA vaccine targeting VEE virus delivered by needle-free jet-injection protects macaques against aerosol challenge

por Suschak, John J., Bixler, Sandra L., Badger, Catherine V., Spik, Kristin W., Kwilas, Steven A., Rossi, Franco D., Twenhafel, Nancy, Adams, Melissa L., Shoemaker, Charles J., Spiegel, Erin, Hooper, Jay W.
Publicado 2022

Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models

por Perley, Casey C., Brocato, Rebecca L., Wu, Hua, Bausch, Christoph, Karmali, Priya P., Vega, Jerel B., Cohen, Melanie V., Somerville, Brandon, Kwilas, Steven A., Principe, Lucia M., Shamblin, Joshua, Chivukula, Padmanabh, Sullivan, Eddie, Hooper, Jay W.
Publicado 2020

Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses

por Bounds, Callie E., Kwilas, Steven A., Kuehne, Ana I., Brannan, Jennifer M., Bakken, Russell R., Dye, John M., Hooper, Jay W., Dupuy, Lesley C., Ellefsen, Barry, Hannaman, Drew, Wu, Hua, Jiao, Jin-an, Sullivan, Eddie J., Schmaljohn, Connie S.
Publicado 2015

Human convalescent plasma protects K18-hACE2 mice against severe respiratory disease

por Golden, Joseph W., Zeng, Xiankun, Cline, Curtis R., Garrison, Aura R., White, Lauren E., Fitzpatrick, Collin J., Kwilas, Steven A., Bowling, Philip A., Fiallos, Jimmy O., Moore, Joshua L., Sifford, Willie B., Ricks, Keersten M., Mucker, Eric M., Smith, Jeffrey M., Hooper, Jay W.
Publicado 2021

Evaluation of a panel of therapeutic antibody clinical candidates for efficacy against SARS-CoV-2 in Syrian hamsters

por Cong, Yu, Mucker, Eric M., Perry, Donna L., Dixit, Saurabh, Kollins, Erin, Byrum, Russ, Huzella, Louis, Kim, Robert, Josleyn, Mathew, Kwilas, Steven, Stefan, Christopher, Shoemaker, Charles J., Koehler, Jeff, Coyne, Susan, Delp, Korey, Liang, Janie, Drawbaugh, David, Hischak, Amanda, Hart, Randy, Postnikova, Elena, Vaughan, Nick, Asher, Jason, St Claire, Marisa, Hanson, Jarod, Schmaljohn, Connie, Eakin, Ann E., Hooper, Jay W., Holbrook, Michael R.
Publicado 2023

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

por Engdahl, Taylor B, Binshtein, Elad, Brocato, Rebecca L, Kuzmina, Natalia A, Principe, Lucia M, Kwilas, Steven A, Kim, Robert K, Chapman, Nathaniel S, Porter, Monique S, Guardado-Calvo, Pablo, Rey, Félix A, Handal, Laura S, Diaz, Summer M, Zagol-Ikapitte, Irene A, Tran, Minh H, McDonald, W Hayes, Meiler, Jens, Reidy, Joseph X, Trivette, Andrew, Bukreyev, Alexander, Hooper, Jay W, Crowe, James E
Publicado 2023