Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery

por Ngan, Kevin Chun-Ho, Hoenig, Samuel M, Kwok, Hui Si, Lue, Nicholas Z, Gosavi, Pallavi M, Tanner, David A, Garcia, Emma M, Lee, Ceejay, Liau, Brian B
Publicado 2023

GCN5 inhibits XBP-1S-mediated transcription by antagonizing PCAF action

por Lew, Qiao Jing, Chu, Kai Ling, Chia, Yi Ling, Soo, Benjamin, Ho, Jia Pei, Ng, Chew Har, Kwok, Hui Si, Chiang, Cheng-Ming, Chang, Yao, Chao, Sheng-Hao
Publicado 2014

Acetylation of C/EBPα inhibits its granulopoietic function

por Bararia, Deepak, Kwok, Hui Si, Welner, Robert S., Numata, Akihiko, Sárosi, Menyhárt B., Yang, Henry, Wee, Sheena, Tschuri, Sebastian, Ray, Debleena, Weigert, Oliver, Levantini, Elena, Ebralidze, Alexander K., Gunaratne, Jayantha, Tenen, Daniel G.
Publicado 2016

TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter

por Rajagopalan, Deepa, Pandey, Amit Kumar, Xiuzhen, Magdalene Claire, Lee, Kwok Kin, Hora, Shainan, Zhang, Yanzhou, Chua, Boon Haow, Kwok, Hui Si, Bhatia, Shreshtha Sailesh, Deng, Lih Wen, Tenen, Daniel G., Kappei, Dennis, Jha, Sudhakar
Publicado 2017

Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer

por Hong, HuiQi, An, Omer, Chan, Tim H M, Ng, Vanessa H E, Kwok, Hui Si, Lin, Jaymie S, Qi, Lihua, Han, Jian, Tay, Daryl J T, Tang, Sze Jing, Yang, Henry, Song, Yangyang, Bellido Molias, Fernando, Tenen, Daniel G, Chen, Leilei
Publicado 2018

Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility

por Leong, David T, Lim, Joleen, Goh, Xuewei, Pratap, Jitesh, Pereira, Barry P, Kwok, Hui Si, Nathan, Saminathan Suresh, Dobson, Jason R, Lian, Jane B, Ito, Yoshiaki, Voorhoeve, P Mathijs, Stein, Gary S, Salto-Tellez, Manuel, Cool, Simon M, van Wijnen, Andre J
Publicado 2010

The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia

por Numata, Akihiko, Kwok, Hui Si, Kawasaki, Akira, Li, Jia, Zhou, Qi-Ling, Kerry, Jon, Benoukraf, Touati, Bararia, Deepak, Li, Feng, Ballabio, Erica, Tapia, Marta, Deshpande, Aniruddha J., Welner, Robert S., Delwel, Ruud, Yang, Henry, Milne, Thomas A., Taneja, Reshma, Tenen, Daniel G.
Publicado 2018