Transcriptomic entropy benchmarks stem cell-derived cardiomyocyte maturation against endogenous tissue at single cell level

por Kannan, Suraj, Farid, Michael, Lin, Brian L., Miyamoto, Matthew, Kwon, Chulan
Publicado 2021

A Regulatory Pathway Involving Notch1/β-Catenin/Isl1 Determines Cardiac Progenitor Cell Fate

por Kwon, Chulan, Qian, Li, Cheng, Paul, Nigam, Vishal, Arnold, Josh, Srivastava, Deepak
Publicado 2009

Direct Contact with Endoderm-Like Cells Efficiently Induces Cardiac Progenitors from Mouse and Human Pluripotent Stem Cells

por Uosaki, Hideki, Andersen, Peter, Shenje, Lincoln T., Fernandez, Laviel, Christiansen, Sofie Lindgren, Kwon, Chulan
Publicado 2012

Maturing heart muscle cells: Mechanisms and transcriptomic insights

por Murphy, Sean A., Chen, Elaine Zhelan, Tung, Leslie, Boheler, Kenneth R., Kwon, Chulan
Publicado 2021

A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation

por Chanthra, Nawin, Abe, Tomoyuki, Miyamoto, Matthew, Sekiguchi, Kiyotoshi, Kwon, Chulan, Hanazono, Yutaka, Uosaki, Hideki
Publicado 2020

Notch Post-Translationally Regulates β-Catenin Protein in Stem and Progenitor Cells

por Kwon, Chulan, Cheng, Paul, King, Isabelle N., Andersen, Peter, Shenje, Lincoln, Nigam, Vishal, Srivastava, Deepak
Publicado 2011

Platform-agnostic CellNet enables cross-study analysis of cell fate engineering protocols

por Lo, Emily K.W., Velazquez, Jeremy J., Peng, Da, Kwon, Chulan, Ebrahimkhani, Mo R., Cahan, Patrick
Publicado 2023

Neurons Derived from Human Induced Pluripotent Stem Cells Integrate into Rat Brain Circuits and Maintain Both Excitatory and Inhibitory Synaptic Activities

por Yin, Xiling, Xu, Jin-Chong, Cho, Gun-sik, Kwon, Chulan, Dawson, Ted M., Dawson, Valina L.
Publicado 2019

Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytes

por Kannan, Suraj, Miyamoto, Matthew, Zhu, Renjun, Lynott, Michaela, Guo, Jason, Chen, Elaine Zhelan, Colas, Alexandre R., Lin, Brian Leei, Kwon, Chulan
Publicado 2023

Sympathetic Neurons Regulate Cardiomyocyte Maturation in Culture

por Kowalski, William J., Garcia-Pak, Iris H., Li, Wenling, Uosaki, Hideki, Tampakakis, Emmanouil, Zou, Jizhong, Lin, Yongshun, Patterson, Kira, Kwon, Chulan, Mukouyama, Yoh-Suke
Publicado 2022

Precardiac organoids form two heart fields via Bmp/Wnt signaling

por Andersen, Peter, Tampakakis, Emmanouil, Jimenez, Dennisse V., Kannan, Suraj, Miyamoto, Matthew, Shin, Hye Kyung, Saberi, Amir, Murphy, Sean, Sulistio, Edrick, Chelko, Stephen P., Kwon, Chulan
Publicado 2018

Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm

por Kervadec, Anaïs, Kezos, James, Ni, Haibo, Yu, Michael, Marchant, James, Spiering, Sean, Kannan, Suraj, Kwon, Chulan, Andersen, Peter, Bodmer, Rolf, Grandi, Eleonora, Ocorr, Karen, Colas, Alexandre R.
Publicado 2023

Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors

por Shenje, Lincoln T, Andersen, Peter, Uosaki, Hideki, Fernandez, Laviel, Rainer, Peter P, Cho, Gun-sik, Lee, Dong-ik, Zhong, Weimin, Harvey, Richard P, Kass, David A, Kwon, Chulan
Publicado 2014

Cardiac progenitors instruct second heart field fate through Wnts

por Miyamoto, Matthew, Kannan, Suraj, Anderson, Matthew J., Liu, Xihe, Suh, David, Htet, Myo, Li, Biyi, Kakani, Tejasvi, Murphy, Sean, Tampakakis, Emmanouil, Lewandoski, Mark, Andersen, Peter, Uosaki, Hideki, Kwon, Chulan
Publicado 2023

Heart neurons use clock genes to control myocyte proliferation

por Tampakakis, Emmanouil, Gangrade, Harshi, Glavaris, Stephanie, Htet, Myo, Murphy, Sean, Lin, Brian Leei, Liu, Ting, Saberi, Amir, Miyamoto, Matthew, Kowalski, William, Mukouyama, Yoh-Suke, Lee, Gabsang, Minichiello, Liliana, Kwon, Chulan
Publicado 2021

PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2

por Murphy, Sean A., Miyamoto, Matthew, Kervadec, Anaïs, Kannan, Suraj, Tampakakis, Emmanouil, Kambhampati, Sandeep, Lin, Brian Leei, Paek, Sam, Andersen, Peter, Lee, Dong-Ik, Zhu, Renjun, An, Steven S., Kass, David A., Uosaki, Hideki, Colas, Alexandre R., Kwon, Chulan
Publicado 2021

Single cell RNA-seq analysis of the flexor digitorum brevis mouse myofibers

por Verma, Rohan X., Kannan, Suraj, Lin, Brian L., Fomchenko, Katherine M., Nieuwenhuis, Tim O., Patil, Arun H., Lukban, Clarisse, Yang, Xiaoping, Fox-Talbot, Karen, McCall, Matthew N., Kwon, Chulan, Kass, David A., Rosenberg, Avi Z., Halushka, Marc K.
Publicado 2021

Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells

por Missinato, Maria A., Murphy, Sean, Lynott, Michaela, Yu, Michael S., Kervadec, Anaïs, Chang, Yu-Ling, Kannan, Suraj, Loreti, Mafalda, Lee, Christopher, Amatya, Prashila, Tanaka, Hiroshi, Huang, Chun-Teng, Puri, Pier Lorenzo, Kwon, Chulan, Adams, Peter D., Qian, Li, Sacco, Alessandra, Andersen, Peter, Colas, Alexandre R.
Publicado 2023

Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease

por Lee, Dong I., Zhu, Guangshuo, Sasaki, Takashi, Cho, Gun-Sik, Hamdani, Nazha, Holewinski, Ronald, Jo, Su-Hyun, Danner, Thomas, Zhang, Manling, Rainer, Peter P., Bedja, Djahida, Kirk, Jonathan A., Ranek, Mark J., Dostmann, Wolfgang R., Kwon, Chulan, Margulies, Kenneth B., Van Eyk, Jennifer E., Paulus, Walter J., Takimoto, Eiki, Kass, David A.
Publicado 2015

Mutations in Alström Protein Impair Terminal Differentiation of Cardiomyocytes

por Shenje, Lincoln T., Andersen, Peter, Halushka, Marc K., Lui, Cecillia, Fernandez, Laviel, Collin, Gayle B., Amat-Alarcon, Nuria, Meschino, Wendy, Cutz, Ernest, Chang, Kenneth, Yonescu, Raluca, Batista, Denise A. S., Chen, Yan, Chelko, Stephen, Crosson, Jane E., Scheel, Janet, Vricella, Luca, Craig, Brian D., Marosy, Beth A., Mohr, David W., Hetrick, Kurt N., Romm, Jane M., Scott, Alan F., Valle, David, Naggert, Jürgen K., Kwon, Chulan, Doheny, Kimberly F., Judge, Daniel P.
Publicado 2014