Immunogenicity and Vaccine Potential of InsB, an ESAT-6-Like Antigen Identified in the Highly Virulent Mycobacterium tuberculosis Beijing K Strain

por Kim, Woo Sik, Kim, Hongmin, Kwon, Kee Woong, Cho, Sang-Nae, Shin, Sung Jae
Publicado 2019

Comparison of immunogenicity and vaccine efficacy between heat-shock proteins, HSP70 and GrpE, in the DnaK operon of Mycobacterium tuberculosis

por Kim, Woo Sik, Kim, Jong-Seok, Kim, Hong Min, Kwon, Kee Woong, Eum, Seok-Yong, Shin, Sung Jae
Publicado 2018

Toll-like receptor 4 signaling-mediated responses are critically engaged in optimal host protection against highly virulent Mycobacterium tuberculosis K infection

por Park, Jaehun, Kim, Hongmin, Kwon, Kee Woong, Choi, Hong-Hee, Kang, Soon Myung, Hong, Jung Joo, Shin, Sung Jae
Publicado 2020

Viral coinfection promotes tuberculosis immunopathogenesis by type I IFN signaling-dependent impediment of Th1 cell pulmonary influx

por Kang, Tae Gun, Kwon, Kee Woong, Kim, Kyungsoo, Lee, Insuk, Kim, Myeong Joon, Ha, Sang-Jun, Shin, Sung Jae
Publicado 2022

Protective Efficacy and Immunogenicity of Rv0351/Rv3628 Subunit Vaccine Formulated in Different Adjuvants Against Mycobacterium tuberculosis Infection

por Kwon, Kee Woong, Kang, Tae Gun, Lee, Ara, Jin, Seung Mo, Lim, Yong Taik, Shin, Sung Jae, Ha, Sang-Jun
Publicado 2023

Cisplatin induces tolerogenic dendritic cells in response to TLR agonists via the abundant production of IL-10, thereby promoting Th2- and Tr1-biased T-cell immunity

por Kim, Woo Sik, Kim, Hongmin, Kwon, Kee Woong, Im, Sin-Hyeog, Lee, Bo Ryeong, Ha, Sang-Jun, Shin, Sung Jae
Publicado 2016

Mycobacterium tuberculosis GrpE, A Heat-Shock Stress Responsive Chaperone, Promotes Th1-Biased T Cell Immune Response via TLR4-Mediated Activation of Dendritic Cells

por Kim, Woo Sik, Jung, In Duk, Kim, Jong-Seok, Kim, Hong Min, Kwon, Kee Woong, Park, Yeong-Min, Shin, Sung Jae
Publicado 2018

An Alternative Dendritic Cell-Induced Murine Model of Asthma Exhibiting a Robust Th2/Th17-Skewed Response

por Park, Sang Chul, Kim, Hongmin, Bak, Yeeun, Shim, Dahee, Kwon, Kee Woong, Kim, Chang-Hoon, Yoon, Joo-Heon, Shin, Sung Jae
Publicado 2020

Plant-Produced N-glycosylated Ag85A Exhibits Enhanced Vaccine Efficacy Against Mycobacterium tuberculosis HN878 Through Balanced Multifunctional Th1 T Cell Immunity

por Kim, Hongmin, Kwon, Kee Woong, Park, Jaehun, Kang, Hyangju, Lee, Yongjik, Sohn, Eun-Ju, Hwang, Inhwan, Eum, Seok-Yong, Shin, Sung Jae
Publicado 2020

Exacerbation of Mycobacterium avium pulmonary infection by comorbid allergic asthma is associated with diminished mycobacterium-specific Th17 responses

por Bak, Yeeun, Park, Sang Chul, Shim, Dahee, Ha, Yura, Lee, Jumi, Kim, Hongmin, Kwon, Kee Woong, Yoon, Joo-Heon, Shin, Sung Jae
Publicado 2021

BCGΔBCG1419c increased memory CD8(+) T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis

por Kwon, Kee Woong, Aceves-Sánchez, Michel de Jesús, Segura-Cerda, Cristian Alfredo, Choi, Eunsol, Bielefeldt-Ohmann, Helle, Shin, Sung Jae, Flores-Valdez, Mario Alberto
Publicado 2022

IL-15 Generates IFN-γ-producing Cells Reciprocally Expressing Lymphoid-Myeloid Markers during Dendritic Cell Differentiation

por Kwon, Kee Woong, Kim, So Jeong, Kim, Hongmin, Kim, Woo Sik, Kang, Soon Myung, Choi, Eunsol, Ha, Sang-Jun, Yoon, Joo-Heon, Shin, Sung Jae
Publicado 2019

Antigen-Specific IFN-γ/IL-17-Co-Producing CD4(+) T-Cells are the Determinants for Protective Efficacy of Tuberculosis Subunit Vaccine

por Choi, Han-Gyu, Kwon, Kee Woong, Choi, Seunga, Back, Yong Woo, Park, Hye-Soo, Kang, Soon Myung, Choi, Eunsol, Shin, Sung Jae, Kim, Hwa-Jung
Publicado 2020

Vaccination inducing durable and robust antigen-specific Th1/Th17 immune responses contributes to prophylactic protection against Mycobacterium avium infection but is ineffective a...

por Lee, Ju Mi, Park, Jiyun, Reed, Steven G, Coler, Rhea N, Hong, Jung Joo, Kim, Lee-Han, Lee, Wonsik, Kwon, Kee Woong, Shin, Sung Jae
Publicado 2022

Repeated Aerosolized-Boosting with Gamma-Irradiated Mycobacterium bovis BCG Confers Improved Pulmonary Protection against the Hypervirulent Mycobacterium tuberculosis Strain HN878...

por Cha, Seung Bin, Kim, Woo Sik, Kim, Jong-Seok, Kim, Hongmin, Kwon, Kee Woong, Han, Seung Jung, Eum, Seok-Yong, Cho, Sang-Nae, Shin, Sung Jae
Publicado 2015

Novel vaccine potential of Rv3131, a DosR regulon-encoded putative nitroreductase, against hyper-virulent Mycobacterium tuberculosis strain K

por Kwon, Kee Woong, Kim, Woo Sik, Kim, Hongmin, Han, Seung Jung, Hahn, Mi-Young, Lee, Jong Seok, Nam, Ki Taek, Cho, Sang-Nae, Shin, Sung Jae
Publicado 2017

Long-term protective efficacy with a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse model

por Kwon, Kee Woong, Lee, Ara, Larsen, Sasha E., Baldwin, Susan L., Coler, Rhea N., Reed, Steven G., Cho, Sang-Nae, Ha, Sang-Jun, Shin, Sung Jae
Publicado 2019

Experimental Reactivation of Pulmonary Mycobacterium avium Complex Infection in a Modified Cornell-Like Murine Model

por Cha, Seung Bin, Jeon, Bo Young, Kim, Woo Sik, Kim, Jong-Seok, Kim, Hong Min, Kwon, Kee Woong, Cho, Sang-Nae, Shin, Sung Jae, Koh, Won-Jung
Publicado 2015

Virulence-Dependent Alterations in the Kinetics of Immune Cells during Pulmonary Infection by Mycobacterium tuberculosis

por Kim, Woo Sik, Kim, Jong-Seok, Cha, Seung Bin, Han, Seung Jung, Kim, HongMin, Kwon, Kee Woong, Kim, So Jeong, Eum, Seok-Yong, Cho, Sang-Nae, Shin, Sung Jae
Publicado 2015

Mycobacterium tuberculosis Rv3628 drives Th1-type T cell immunity via TLR2-mediated activation of dendritic cells and displays vaccine potential against the hyper-virulent Beijing...

por Kim, Woo Sik, Kim, Jong-Seok, Cha, Seung Bin, Kim, Hongmin, Kwon, Kee Woong, Kim, So Jeong, Han, Seung Jung, Choi, Soo Young, Cho, Sang-Nae, Park, Jong-Hwan, Shin, Sung Jae
Publicado 2016