miRNAs, Melanoma and Microenvironment: An Intricate Network

por Romano, Gabriele, Kwong, Lawrence N.
Publicado 2017

Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression

por Roszik, Jason, Wu, Chang-Jiun, Siroy, Alan E., Lazar, Alexander J., Davies, Michael A, Woodman, Scott E, Kwong, Lawrence N
Publicado 2016

Generation of An Endogenous FGFR2–BICC1 Gene Fusion/58 Megabase Inversion Using Single-Plasmid CRISPR/Cas9 Editing in Biliary Cells

por Reicher, Andreas, Harris, Antoneicka L, Prinz, Felix, Kiesslich, Tobias, Wei, Miaoyan, Öllinger, Rupert, Rad, Roland, Pichler, Martin, Kwong, Lawrence N
Publicado 2020

High sensitivity sanger sequencing detection of BRAF mutations in metastatic melanoma FFPE tissue specimens

por Cheng, Lauren Y., Haydu, Lauren E., Song, Ping, Nie, Jianyi, Tetzlaff, Michael T., Kwong, Lawrence N., Gershenwald, Jeffrey E., Davies, Michael A., Zhang, David Yu
Publicado 2021

Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models

por Lee, Michael S., Helms, Timothy L., Feng, Ningping, Gay, Jason, Chang, Qing Edward, Tian, Feng, Wu, Ji Y., Toniatti, Carlo, Heffernan, Timothy P., Powis, Garth, Kwong, Lawrence N., Kopetz, Scott
Publicado 2016

Genomic profiling reveals high frequency of DNA repair genetic aberrations in gallbladder cancer

por Abdel-Wahab, Reham, Yap, Timothy A., Madison, Russell, Pant, Shubham, Cooke, Matthew, Wang, Kai, Zhao, Haitao, Bekaii-Saab, Tanios, Karatas, Elif, Kwong, Lawrence N., Meric-Bernstam, Funda, Borad, Mitesh, Javle, Milind
Publicado 2020

Targeting RAS Mutant Colorectal Cancer with Dual Inhibition of MEK and CDK4/6

por Sorokin, Alexey V., Kanikarla Marie, Preeti, Bitner, Lea, Syed, Muddassir, Woods, Melanie, Manyam, Ganiraju, Kwong, Lawrence N., Johnson, Benny, Morris, Van K., Jones, Philip, Menter, David G., Lee, Michael S., Kopetz, Scott
Publicado 2022

USP1 promotes cholangiocarcinoma progression by deubiquitinating PARP1 to prevent its proteasomal degradation

por Zhang, Deng Yong, Zhu, Yan, Wu, Qiong, Ma, Shuoshuo, Ma, Yang, Shen, Zheng chao, Wang, Zhonglin, Sun, Wanliang, Zhou, Yong Chun, Wang, Dongdong, Zhou, Shuo, Liu, Zhong, Kwong, Lawrence N., Lu, Zheng
Publicado 2023

Integrative Genome Comparison of Primary and Metastatic Melanomas

por Kabbarah, Omar, Nogueira, Cristina, Feng, Bin, Nazarian, Rosalynn M., Bosenberg, Marcus, Wu, Min, Scott, Kenneth L., Kwong, Lawrence N., Xiao, Yonghong, Cordon-Cardo, Carlos, Granter, Scott R., Ramaswamy, Sridhar, Golub, Todd, Duncan, Lyn M., Wagner, Stephan N., Brennan, Cameron, Chin, Lynda
Publicado 2010

Intrahepatic Cholangiocarcinoma: Genomic Heterogeneity Between Eastern and Western Patients

por Cao, Jingyu, Hu, Jing, Liu, Siqin, Meric-Bernstam, Funda, Abdel-Wahab, Reham, Xu, Junjie, Li, Qiang, Yan, Maolin, Feng, Yujie, Lin, Jianzhen, Zhao, Songhui, Wang, Jian, Kwong, Lawrence N., Hu, Jinwei, Carapeto, Fernando, Borad, Mitesh J., Wang, Kai, Javle, Milind, Zhao, Haitao
Publicado 2020

Clinical Profiling of BCL-2 Family Members in the Setting of BRAF Inhibition Offers a Rationale for Targeting De Novo Resistance Using BH3 Mimetics

por Frederick, Dennie T., Salas Fragomeni, Roberto A., Schalck, Aislyn, Ferreiro-Neira, Isabel, Hoff, Taylor, Cooper, Zachary A., Haq, Rizwan, Panka, David J., Kwong, Lawrence N., Davies, Michael A., Cusack, James C., Flaherty, Keith T., Fisher, David E., Mier, James W., Wargo, Jennifer A., Sullivan, Ryan J.
Publicado 2014

Oncogenic Kras drives invasion and maintains metastases in colorectal cancer

por Boutin, Adam T., Liao, Wen-Ting, Wang, Melody, Hwang, Soyoon Sarah, Karpinets, Tatiana V., Cheung, Hannah, Chu, Gerald C., Jiang, Shan, Hu, Jian, Chang, Kyle, Vilar, Eduardo, Song, Xingzhi, Zhang, Jianhua, Kopetz, Scott, Futreal, Andrew, Wang, Y. Alan, Kwong, Lawrence N., DePinho, Ronald A.
Publicado 2017

Multi-modal molecular programs regulate melanoma cell state

por Andrews, Miles C., Oba, Junna, Wu, Chang-Jiun, Zhu, Haifeng, Karpinets, Tatiana, Creasy, Caitlin A., Forget, Marie-Andrée, Yu, Xiaoxing, Song, Xingzhi, Mao, Xizeng, Robertson, A. Gordon, Romano, Gabriele, Li, Peng, Burton, Elizabeth M., Lu, Yiling, Sloane, Robert Szczepaniak, Wani, Khalida M., Rai, Kunal, Lazar, Alexander J., Haydu, Lauren E., Bustos, Matias A., Shen, Jianjun, Chen, Yueping, Morgan, Margaret B., Wargo, Jennifer A., Kwong, Lawrence N., Haymaker, Cara L., Grimm, Elizabeth A., Hwu, Patrick, Hoon, Dave S. B., Zhang, Jianhua, Gershenwald, Jeffrey E., Davies, Michael A., Futreal, P. Andrew, Bernatchez, Chantale, Woodman, Scott E.
Publicado 2022

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

por Farshidfar, Farshad, Zheng, Siyuan, Gingras, Marie-Claude, Newton, Yulia, Shih, Juliann, Robertson, A. Gordon, Hinoue, Toshinori, Hoadley, Katherine A., Gibb, Ewan A., Roszik, Jason, Covington, Kyle R., Wu, Chia-Chin, Shinbrot, Eve, Stransky, Nicolas, Hegde, Apurva, Yang, Ju Dong, Reznik, Ed, Sadeghi, Sara, Pedamallu, Chandra Sekhar, Ojesina, Akinyemi I., Hess, Julian M., Auman, J. Todd, Rhie, Suhn K., Bowlby, Reanne, Borad, Mitesh J., Zhu, Andrew X., Stuart, Josh M., Sander, Chris, Akbani, Rehan, Cherniack, Andrew D., Deshpande, Vikram, Mounajjed, Taofic, Foo, Wai Chin, Torbenson, Michael S., Kleiner, David E., Laird, Peter W., Wheeler, David A., McRee, Autumn J., Bathe, Oliver F., Andersen, Jesper B., Bardeesy, Nabeel, Roberts, Lewis R., Kwong, Lawrence N.
Publicado 2017

Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance

por Liu, Jianglan, Rebecca, Vito W., Kossenkov, Andrew V., Connelly, Thomas, Liu, Qin, Gutierrez, Alexis, Xiao, Min, Li, Ling, Zhang, Gao, Samarkina, Anastasia, Zayasbazan, Delaine, Zhang, Jie, Cheng, Chaoran, Wei, Zhi, Alicea, Gretchen M., Fukunaga-Kalabis, Mizuho, Krepler, Clemens, Aza-Blanc, Pedro, Yang, Chih-Cheng, Delvadia, Bela, Tong, Cynthia, Huang, Ye, Delvadia, Maya, Morias, Alice S., Sproesser, Katrin, Brafford, Patricia, Wang, Joshua X., Beqiri, Marilda, Somasundaram, Rajasekharan, Vultur, Adina, Hristova, Denitsa M., Wu, Lawrence W., Lu, Yiling, Mills, Gordon B., Xu, Wei, Karakousis, Giorgos C., Xu, Xiaowei, Schuchter, Lynn M., Mitchell, Tara C., Amaravadi, Ravi K., Kwong, Lawrence N., Frederick, Dennie T., Boland, Genevieve M., Salvino, Joseph M., Speicher, David W., Flaherty, Keith T., Ronai, Ze'ev A., Herlyn, Meenhard
Publicado 2021