The Ile191Val Variant of the TAS1R2 Subunit of Sweet Taste Receptors Is Associated With Reduced HbA(1c) in a Human Cohort With Variable Levels of Glucose Homeostasis

por Serrano, Joan, Yi, Fanchao, Smith, Joshua, Pratley, Richard E., Kyriazis, George A.
Publicado 2022

“Tasting” fructose with pancreatic beta-cells: modulation of insulin release by sweet taste receptor signaling and its role in metabolic diseases

por Kyriazis, George A, Mosure, Kathleen R, Soundarapandian, Mangala M, Pratley, Richard E, Tyrberg, Björn
Publicado 2012

Saccharin Stimulates Insulin Secretion Dependent on Sweet Taste Receptor-Induced Activation of PLC Signaling Axis

por Serrano, Joan, Meshram, Nishita N., Soundarapandian, Mangala M., Smith, Kathleen R., Mason, Carter, Brown, Ian S., Tyrberg, Björn, Kyriazis, George A.
Publicado 2022

The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans

por Serrano, Joan, Seflova, Jaroslava, Park, Jihye, Pribadi, Marsha, Sanematsu, Keisuke, Shigemura, Noriatsu, Serna, Vanida, Yi, Fanchao, Mari, Andrea, Procko, Erik, Pratley, Richard E., Robia, Seth L., Kyriazis, George A.
Publicado 2021

Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function

por Longenecker, Jacob Z., Petrosino, Jennifer M., Martens, Colton R., Hinger, Scott A., Royer, Charlotte J., Dorn, Lisa E., Branch, Daniel A., Serrano, Joan, Stanford, Kristin I., Kyriazis, George A., Baskin, Kedryn K., Accornero, Federica
Publicado 2021

T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways

por Smith, Kathleen, Karimian Azari, Elnaz, LaMoia, Traci E., Hussain, Tania, Vargova, Veronika, Karolyi, Katalin, Veldhuis, Paula P., Arnoletti, Juan Pablo, de la Fuente, Sebastian G., Pratley, Richard E., Osborne, Timothy F., Kyriazis, George A.
Publicado 2018

High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

por Serrano, Joan, Smith, Kathleen R., Crouch, Audra L., Sharma, Vandana, Yi, Fanchao, Vargova, Veronika, LaMoia, Traci E., Dupont, Lydia M., Serna, Vanida, Tang, Fenfen, Gomes-Dias, Laisa, Blakeslee, Joshua J., Hatzakis, Emmanuel, Peterson, Scott N., Anderson, Matthew, Pratley, Richard E., Kyriazis, George A.
Publicado 2021

The TAS1R2 sweet taste receptor regulates skeletal muscle mass and fitness

por Serrano, Joan, Boyd, Jordan, Mason, Carter, Smith, Kathleen R, Karolyi, Katalin, Kondo, Saki, Brown, Ian S, Maurya, Santosh K, Meshram, Nishita N, Serna, Vanida, Gilger, Joshua, Branch, Daniel A, Gardell, Stephen J, Baskin, Kedryn K, Ayala, Julio E, Pratley, Richard E, Goodpaster, Bret H, Coen, Paul M, Kyriazis, George A
Publicado 2023

NIH Workshop Report: sensory nutrition and disease

por Reed, Danielle R, Alhadeff, Amber L, Beauchamp, Gary K, Chaudhari, Nirupa, Duffy, Valerie B, Dus, Monica, Fontanini, Alfredo, Glendinning, John I, Green, Barry G, Joseph, Paule V, Kyriazis, George A, Lyte, Mark, Maruvada, Padma, McGann, John P, McLaughlin, John T, Moran, Timothy H, Murphy, Claire, Noble, Emily E, Pepino, M Yanina, Pluznick, Jennifer L, Rother, Kristina I, Saez, Enrique, Spector, Alan C, Sternini, Catia, Mattes, Richard D
Publicado 2020