Genome interpretation in a federated learning context allows the multi-center exome-based risk prediction of Crohn’s disease patients

por Raimondi, Daniele, Chizari, Haleh, Verplaetse, Nora, Löscher, Britt-Sabina, Franke, Andre, Moreau, Yves
Publicado 2023

Current Developments of Clinical Sequencing and the Clinical Utility of Polygenic Risk Scores in Inflammatory Diseases

por Hübenthal, Matthias, Löscher, Britt-Sabina, Erdmann, Jeanette, Franke, Andre, Gola, Damian, König, Inke R., Emmert, Hila
Publicado 2021

Adult sucrase-isomaltase deficiency masquerading as IBS

por Foley, Anna, Halmos, Emma Phoebe, Husein, Diab M, Fehily, Sasha Rachel, Löscher, Britt-Sabina, Franke, Andre, Naim, Hassan Y, Gibson, Peter R, D'Amato, Mauro
Publicado 2022

Exome sequencing in 38 patients with intracranial aneurysms and subarachnoid hemorrhage

por Sauvigny, Thomas, Alawi, Malik, Krause, Linda, Renner, Sina, Spohn, Michael, Busch, Alice, Kolbe, Verena, Altmüller, Janine, Löscher, Britt-Sabina, Franke, Andre, Brockmann, Christian, Lieb, Wolfgang, Westphal, Manfred, Schmidt, Nils Ole, Regelsberger, Jan, Rosenberger, Georg
Publicado 2020

Genetic Variation in ABCC4 and CFTR and Acute Pancreatitis during Treatment of Pediatric Acute Lymphoblastic Leukemia

por Bartram, Thies, Schütte, Peter, Möricke, Anja, Houlston, Richard S., Ellinghaus, Eva, Zimmermann, Martin, Bergmann, Anke, Löscher, Britt-Sabina, Klein, Norman, Hinze, Laura, Junk, Stefanie V., Forster, Michael, Bartram, Claus R., Köhler, Rolf, Franke, Andre, Schrappe, Martin, Kratz, Christian P., Cario, Gunnar, Stanulla, Martin
Publicado 2021

SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation

por Južnić, Lea, Peuker, Kenneth, Strigli, Anne, Brosch, Mario, Herrmann, Alexander, Häsler, Robert, Koch, Michael, Matthiesen, Liz, Zeissig, Yvonne, Löscher, Britt-Sabina, Nuber, Alexander, Schotta, Gunnar, Neumeister, Volker, Chavakis, Triantafyllos, Kurth, Thomas, Lesche, Mathias, Dahl, Andreas, von Mässenhausen, Anne, Linkermann, Andreas, Schreiber, Stefan, Aden, Konrad, Rosenstiel, Philip C, Franke, Andre, Hampe, Jochen, Zeissig, Sebastian
Publicado 2021

Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease

por Ziegler, Jörn F., Böttcher, Chotima, Letizia, Marilena, Yerinde, Cansu, Wu, Hao, Freise, Inka, Rodriguez-Sillke, Yasmina, Stoyanova, Ani K., Kreis, Martin E., Asbach, Patrick, Kunkel, Desiree, Priller, Josef, Anagnostopoulos, Ioannis, Kühl, Anja A., Miehle, Konstanze, Stumvoll, Michael, Tran, Florian, Fredrich, Broder, Forster, Michael, Franke, Andre, Bojarski, Christian, Glauben, Rainer, Löscher, Britt-Sabina, Siegmund, Britta, Weidinger, Carl
Publicado 2019

Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases

por De La Vega, Francisco M., Chowdhury, Shimul, Moore, Barry, Frise, Erwin, McCarthy, Jeanette, Hernandez, Edgar Javier, Wong, Terence, James, Kiely, Guidugli, Lucia, Agrawal, Pankaj B., Genetti, Casie A., Brownstein, Catherine A., Beggs, Alan H., Löscher, Britt-Sabina, Franke, Andre, Boone, Braden, Levy, Shawn E., Õunap, Katrin, Pajusalu, Sander, Huentelman, Matt, Ramsey, Keri, Naymik, Marcus, Narayanan, Vinodh, Veeraraghavan, Narayanan, Billings, Paul, Reese, Martin G., Yandell, Mark, Kingsmore, Stephen F.
Publicado 2021