A two-dose heterologous prime-boost vaccine regimen eliciting sustained immune responses to Ebola Zaire could support a preventive strategy for future outbreaks

por Shukarev, Georgi, Callendret, Benoit, Luhn, Kerstin, Douoguih, Macaya
Publicado 2016

Safety and Immunogenicity of a 2-Dose Heterologous Vaccine Regimen With Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccines: 12-Month Data From a Phase 1 Randomized Clinical Trial in Nairobi...

por Mutua, Gaudensia, Anzala, Omu, Luhn, Kerstin, Robinson, Cynthia, Bockstal, Viki, Anumendem, Dickson, Douoguih, Macaya
Publicado 2019

Safety and Immunogenicity of Heterologous and Homologous 2-Dose Regimens of Adenovirus Serotype 26– and Modified Vaccinia Ankara–Vectored Ebola Vaccines: A Randomized, Controlled P...

por Goldstein, Neil, Bockstal, Viki, Bart, Stephan, Luhn, Kerstin, Robinson, Cynthia, Gaddah, Auguste, Callendret, Benoit, Douoguih, Macaya
Publicado 2020

Impact of prophylactic vaccination strategies on Ebola virus transmission: A modeling analysis

por Potluri, Ravi, Kumar, Amit, Maheshwari, Vikalp, Smith, Charlie, Oriol Mathieu, Valerie, Luhn, Kerstin, Callendret, Benoit, Bhandari, Hitesh
Publicado 2020

A Novel Strategy for Inducing Enhanced Mucosal HIV-1 Antibody Responses in an Anti-Inflammatory Environment

por Wegmann, Frank, Krashias, George, Lühn, Kerstin, Laamanen, Karoliina, Vieira, Sueli, Jeffs, Simon A., Shattock, Robin J., Sattentau, Quentin J.
Publicado 2011

Assessments of different batches and dose levels of a two-dose Ad26.ZEBOV and MVA-BN-Filo vaccine regimen

por Bockstal, Viki, Gaddah, Auguste, Goldstein, Neil, Shukarev, Georgi, Bart, Stephan, Luhn, Kerstin, Robinson, Cynthia, Anumendem, Dickson, Leyssen, Maarten, Douoguih, Macaya
Publicado 2021

Durable natural killer cell responses after heterologous two-dose Ebola vaccination

por Wagstaffe, Helen R., Susannini, Giada, Thiébaut, Rodolphe, Richert, Laura, Lévy, Yves, Bockstal, Viki, Stoop, Jeroen N., Luhn, Kerstin, Douoguih, Macaya, Riley, Eleanor M., Lacabaratz, Christine, Goodier, Martin R.
Publicado 2021

Ebola virus glycoprotein stimulates IL-18–dependent natural killer cell responses

por Wagstaffe, Helen R., Clutterbuck, Elizabeth A., Bockstal, Viki, Stoop, Jeroen N., Luhn, Kerstin, Douoguih, Macaya, Shukarev, Georgi, Snape, Matthew D., Pollard, Andrew J., Riley, Eleanor M., Goodier, Martin R.
Publicado 2020

Antibody-Dependent Natural Killer Cell Activation After Ebola Vaccination

por Wagstaffe, Helen R, Clutterbuck, Elizabeth A, Bockstal, Viki, Stoop, Jeroen N, Luhn, Kerstin, Douoguih, Macaya, Shukarev, Georgi, Snape, Matthew D, Pollard, Andrew J, Riley, Eleanor M, Goodier, Martin R
Publicado 2019

NK Cell Subset Redistribution and Antibody Dependent Activation after Ebola Vaccination in Africans

por Wagstaffe, Helen R., Anzala, Omu, Kibuuka, Hannah, Anywaine, Zacchaeus, Sirima, Sodiomon B., Thiébaut, Rodolphe, Richert, Laura, Levy, Yves, Lacabaratz, Christine, Bockstal, Viki, Luhn, Kerstin, Douoguih, Macaya, Goodier, Martin R.
Publicado 2022

Protection against Marburg Virus and Sudan Virus in NHP by an Adenovector-Based Trivalent Vaccine Regimen Is Correlated to Humoral Immune Response Levels

por Tiemessen, Machteld M., Solforosi, Laura, Dekking, Liesbeth, Czapska-Casey, Dominika, Serroyen, Jan, Sullivan, Nancy J., Volkmann, Ariane, Pau, Maria Grazia, Callendret, Benoit, Schuitemaker, Hanneke, Luhn, Kerstin, Zahn, Roland, Roozendaal, Ramon
Publicado 2022

Safety and Immunogenicity of a 2-Dose Heterologous Vaccination Regimen With Ad26.ZEBOV and MVA-BN-Filo Ebola Vaccines: 12-Month Data From a Phase 1 Randomized Clinical Trial in Uga...

por Anywaine, Zacchaeus, Whitworth, Hilary, Kaleebu, Pontiano, Praygod, George, Shukarev, Georgi, Manno, Daniela, Kapiga, Saidi, Grosskurth, Heiner, Kalluvya, Samuel, Bockstal, Viki, Anumendem, Dickson, Luhn, Kerstin, Robinson, Cynthia, Douoguih, Macaya, Watson-Jones, Deborah
Publicado 2019

High Pro-Inflammatory Cytokine Secretion and Loss of High Avidity Cross-Reactive Cytotoxic T-Cells during the Course of Secondary Dengue Virus Infection

por Dong, Tao, Moran, Edward, Vinh Chau, Nguyen, Simmons, Cameron, Luhn, Kerstin, Peng, Yanchun, Wills, Bridget, Phuong Dung, Nguyen, Thi Thu Thao, Le, Hien, Tran Tinh, McMichael, Andrew, Farrar, Jeremy, Rowland-Jones, Sarah
Publicado 2007

Leukocyte adhesion deficiency II syndrome, a generalized defect in fucose metabolism()()

por Marquardt, Thorsten, Brune, Thomas, Lühn, Kerstin, Zimmer, Klaus-Peter, Körner, Christian, Fabritz, Larissa, van der Werft, Natascha, Vormoor, Josef, Freeze, Hudson H., Louwen, Frank, Biermann, Bettina, Harms, Eric, von Figura, Kurt, Vestweber, Dietmar, Koch, Hans Georg
Publicado 1999

Non-human primate to human immunobridging demonstrates a protective effect of Ad26.ZEBOV, MVA-BN-Filo vaccine against Ebola

por Bockstal, Viki, Leyssen, Maarten, Heerwegh, Dirk, Spiessens, Bart, Robinson, Cynthia, Stoop, Jeroen N., Roozendaal, Ramon, Van Effelterre, Thierry, Gaddah, Auguste, Van Roey, Griet A., Solforosi, Laura, Zahn, Roland, Callendret, Benoit, Hendriks, Jenny, Luhn, Kerstin, Douoguih, Macaya, Schuitemaker, Hanneke, Van Hoof, Johan
Publicado 2022

Persistence of immunological memory as a potential correlate of long-term, vaccine-induced protection against Ebola virus disease in humans

por McLean, Chelsea, Dijkman, Karin, Gaddah, Auguste, Keshinro, Babajide, Katwere, Michael, Douoguih, Macaya, Robinson, Cynthia, Solforosi, Laura, Czapska-Casey, Dominika, Dekking, Liesbeth, Wollmann, Yvonne, Volkmann, Ariane, Pau, Maria Grazia, Callendret, Benoit, Sadoff, Jerry, Schuitemaker, Hanneke, Zahn, Roland, Luhn, Kerstin, Hendriks, Jenny, Roozendaal, Ramon
Publicado 2023

Increased frequencies of CD4(+)CD25(high) regulatory T cells in acute dengue infection

por Lühn, Kerstin, Simmons, Cameron P., Moran, Edward, Dung, Nguyen Thi Phuong, Chau, Tran Nguyen Bich, Quyen, Nguyen Than Ha, Thao, Le Thi Thu, Van Ngoc, Tran, Dung, Nguyen Minh, Wills, Bridget, Farrar, Jeremy, McMichael, Andrew J., Dong, Tao, Rowland-Jones, Sarah
Publicado 2007

Protocol for a phase 3 trial to evaluate the effectiveness and safety of a heterologous, two-dose vaccine for Ebola virus disease in the Democratic Republic of the Congo

por Watson-Jones, Deborah, Kavunga-Membo, Hugo, Grais, Rebecca F, Ahuka, Steve, Roberts, Natalie, Edmunds, W John, Choi, Edward M, Roberts, Chrissy H, Edwards, Tansy, Camacho, Anton, Lees, Shelley, Leyssen, Maarten, Spiessens, Bart, Luhn, Kerstin, Douoguih, Macaya, Hatchett, Richard, Bausch, Daniel G, Muyembe, Jean-Jacques
Publicado 2022

First-in-human study to evaluate safety, tolerability, and immunogenicity of heterologous regimens using the multivalent filovirus vaccines Ad26.Filo and MVA-BN-Filo administered i...

por Bockstal, Viki, Shukarev, Georgi, McLean, Chelsea, Goldstein, Neil, Bart, Stephan, Gaddah, Auguste, Anumenden, Dickson, Stoop, Jeroen N., Marit de Groot, Anne, Pau, Maria G., Hendriks, Jenny, De Rosa, Stephen C., Cohen, Kristen W., McElrath, M. Juliana, Callendret, Benoit, Luhn, Kerstin, Douoguih, Macaya, Robinson, Cynthia
Publicado 2022

Safety and immunogenicity of 2-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccination in healthy and HIV-infected adults: A randomised, placebo-controlled Phase II clinical tr...

por Barry, Houreratou, Mutua, Gaudensia, Kibuuka, Hannah, Anywaine, Zacchaeus, Sirima, Sodiomon B., Meda, Nicolas, Anzala, Omu, Eholie, Serge, Bétard, Christine, Richert, Laura, Lacabaratz, Christine, McElrath, M. Juliana, De Rosa, Stephen, Cohen, Kristen W., Shukarev, Georgi, Robinson, Cynthia, Gaddah, Auguste, Heerwegh, Dirk, Bockstal, Viki, Luhn, Kerstin, Leyssen, Maarten, Douoguih, Macaya, Thiébaut, Rodolphe
Publicado 2021