Microenvironmental Targets in Sarcoma

por Ehnman, Monika, Larsson, Olle
Publicado 2015

Role of Ubiquitination in IGF-1 Receptor Signaling and Degradation

por Sehat, Bita, Andersson, Sandra, Vasilcanu, Radu, Girnita, Leonard, Larsson, Olle
Publicado 2007

Detection of EWS/FLI-1 by Immunostaining. An Adjunctive Tool in Diagnosis of Ewing's Sarcoma and Primitive Neuroectodermal Tumour on Cytological Samples and Paraffin-Embedded Archi...

por Nilsson, Gunnar, Wang, Min, Wejde, Johan, Kreicbergs, Andris, Larsson, Olle
Publicado 1999

Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein

por Warsito, Dudi, Lin, Yingbo, Gnirck, Ann-Christin, Sehat, Bita, Larsson, Olle
Publicado 2016

Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: Clinical implications

por FENG, XIAOYING, ALEEM, EIMAN, LIN, YINGBO, AXELSON, MAGNUS, LARSSON, OLLE, STRÖMBERG, THOMAS
Publicado 2011

Phase I clinical trial of AXL1717 for treatment of relapsed malignant astrocytomas: analysis of dose and response

por Aiken, Robert, Axelson, Magnus, Harmenberg, Johan, Klockare, Maria, Larsson, Olle, Wassberg, Cecilia
Publicado 2017

Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MM...

por Åhlén, Jan, Enberg, Ulla, Larsson, Catharina, Larsson, Olle, Frisk, Tony, Brosjö, Otte, Rosen, Anette von, Bäckdahl, Martin
Publicado 2001

SUMO‐modified insulin‐like growth factor 1 receptor (IGF‐1R) increases cell cycle progression and cell proliferation

por Lin, Yingbo, Liu, Hongyu, Waraky, Ahmed, Haglund, Felix, Agarwal, Prasoon, Jernberg‐Wiklund, Helena, Warsito, Dudi, Larsson, Olle
Publicado 2017

Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism

por Waraky, Ahmed, Akopyan, Karen, Parrow, Vendela, Strömberg, Thomas, Axelson, Magnus, Abrahmsén, Lars, Lindqvist, Arne, Larsson, Olle, Aleem, Eiman
Publicado 2014

TERT promoter mutation is an objective clinical marker for disease progression in chondrosarcoma

por Zhang, Yifan, Chen, Yi, Yang, Chen, Seger, Nelly, Hesla, Asle C., Tsagkozis, Panagiotis, Larsson, Olle, Lin, Yingbo, Haglund, Felix
Publicado 2021

Transcriptome profiling of Ewing sarcomas – treatment resistance pathways and IGF‐dependency

por Chen, Yi, Hesla, Asle C., Lin, Yingbo, Ghaderi, Mehran, Liu, Mingzhi, Yang, Chen, Zhang, Yifan, Tsagkozis, Panagiotis, Larsson, Olle, Haglund, Felix
Publicado 2020

Correction: Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK(+) T-cell lymphoma

por George, Bhawana, George, Suraj Konnath, Shi, Wenyu, Haque, Abedul, Shi, Ping, Eskandari, Ghazaleh, Axelson, Magnus, Larsson, Olle, Kaseb, Ahmed O., Amin, Hesham M.
Publicado 2023

Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK(+) T-cell lymphoma

por George, Bhawana, George, Suraj Konnath, Shi, Wenyu, Haque, Abedul, Shi, Ping, Eskandari, Ghazaleh, Axelson, Magnus, Larsson, Olle, Kaseb, Ahmed O., Amin, Hesham M.
Publicado 2019

Nuclear IGF1R interacts with NuMA and regulates 53BP1-dependent DNA double-strand break repair in colorectal cancer

por Yang, Chen, Zhang, Yifan, Segar, Nelly, Huang, Changhao, Zeng, Pengwei, Tan, Xiangzhou, Mao, Linfeng, Chen, Zhikang, Haglund, Felix, Larsson, Olle, Chen, Zihua, Lin, Yingbo
Publicado 2021

Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers

por Yang, Chen, Zhang, Yifan, Chen, Yi, Ragaller, Franziska, Liu, Mingzhi, Corvigno, Sara, Dahlstrand, Hanna, Carlson, Joseph, Chen, Zihua, Näsman, Anders, Waraky, Ahmed, Lin, Yingbo, Larsson, Olle, Haglund, Felix
Publicado 2020

Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP)

por Hashemi, Jamileh, Worrall, Claire, Vasilcanu, Daiana, Fryknäs, Mårten, Sulaiman, Luqman, Karimi, Mohsen, Weng, Wen-Hui, Lui, Weng-Onn, Rudduck, Christina, Axelson, Magnus, Jernberg-Wiklund, Helena, Girnita, Leonard, Larsson, Olle, Larsson, Catharina
Publicado 2011

HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat

por Angelika Ihle, Michaela, Merkelbach‐Bruse, Sabine, Hartmann, Wolfgang, Bauer, Sebastian, Ratner, Nancy, Sonobe, Hiroshi, Nishio, Jun, Larsson, Olle, Åman, Pierre, Pedeutour, Florence, Taguchi, Takahiro, Wardelmann, Eva, Buettner, Reinhard, Schildhaus, Hans‐Ulrich
Publicado 2016

The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic

por Bieghs, Liesbeth, Lub, Susanne, Fostier, Karel, Maes, Ken, Van Valckenborgh, Els, Menu, Eline, Johnsen, Hans E., Overgaard, Michael T., Larsson, Olle, Axelson, Magnus, Nyegaard, Mette, Schots, Rik, Jernberg-Wiklund, Helena, Vanderkerken, Karin, De Bruyne, Elke
Publicado 2014

Phenotypic Screen Identifies a Small Molecule Modulating ERK2 and Promoting Stem Cell Proliferation

por Yin, Chang, Fufa, Temesgen, Chandrasekar, Gayathri, Aeluri, Madhu, Zaky, Verina, Abdelhady, Shaimaa, Rodríguez, Antonio B., Jakobsson, Johan, Varnoosfaderani, Farzaneh Shahin, Mahalingam, Jayashri, Liu, Jianping, Larsson, Olle, Hovatta, Outi, Gaunitz, Frank, Göndör, Anita, Andäng, Michael, Kitambi, Satish S.
Publicado 2017

SS18-SSX drives CREB activation in synovial sarcoma

por Cyra, Magdalene, Schulte, Miriam, Berthold, Ruth, Heinst, Lorena, Jansen, Esther-Pia, Grünewald, Inga, Elges, Sandra, Larsson, Olle, Schliemann, Christoph, Steinestel, Konrad, Hafner, Susanne, Simmet, Thomas, Wardelmann, Eva, Kailayangiri, Sareetha, Rossig, Claudia, Isfort, Ilka, Trautmann, Marcel, Hartmann, Wolfgang
Publicado 2022