Physiologically Based Pharmacokinetic Modeling: Methodology, Applications, and Limitations with a Focus on Its Role in Pediatric Drug Development

por Khalil, Feras, Läer, Stephanie
Publicado 2011

Drug use patterns for the prevention of paediatric low cardiac output syndrome in Europe

por Vogt, Winnie, Läer, Stephanie
Publicado 2011

Physiologically Based Pharmacokinetic Models in the Prediction of Oral Drug Exposure Over the Entire Pediatric Age Range—Sotalol as a Model Drug

por Khalil, Feras, Läer, Stephanie
Publicado 2014

A Physiologically Based Pharmacokinetic Drug–Disease Model to Predict Carvedilol Exposure in Adult and Paediatric Heart Failure Patients by Incorporating Pathophysiological Changes...

por Rasool, Muhammad Fawad, Khalil, Feras, Läer, Stephanie
Publicado 2015

Model-dependent pharmacokinetic analysis of enalapril administered to healthy adult volunteers using orodispersible minitablets for use in pediatrics

por Faisal, Muhammad, Cawello, Willi, Burckhardt, Bjoern B, Laer, Stephanie
Publicado 2019

EMDIA Case Series—Effective Medication Therapy Management (MTM) for Diabetes Type 2 Patients—A Proof of Concept Study

por Deters, Maira Anna, Obarcanin, Emina, Schwender, Holger, Läer, Stephanie
Publicado 2021

Perinatal Pharmacology

por Allegaert, Karel, Fanos, Vassilios, van den Anker, Johannes N., Laër, Stephanie
Publicado 2014

Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible Minitab...

por Faisal, Muhammad, Cawello, Willi, Burckhardt, Bjoern B., de Hoon, Jan, Laer, Stephanie
Publicado 2019

Pharmacotherapeutic management of paediatric heart failure and ACE-I use patterns: a European survey

por Castro Díez, Cristina, Khalil, Feras, Schwender, Holger, Dalinghaus, Michiel, Jovanovic, Ida, Makowski, Nina, Male, Christoph, Bajcetic, Milica, van der Meulen, Marijke, de Wildt, Saskia N, Ablonczy, László, Szatmári, András, Klingmann, Ingrid, Walsh, Jennifer, Läer, Stephanie
Publicado 2019

Simulation Training to Improve Informed Consent and Pharmacokinetic/Pharmacodynamic Sampling in Pediatric Trials

por Burckhardt, Bjoern B., Ciplea, Agnes Maria, Laven, Anna, Ablonczy, László, Klingmann, Ingrid, Läer, Stephanie, Kleine, Karl, Dalinghaus, Michiel, Đukić, Milan, Breur, Johannes M. P. J., van der Meulen, Marijke, Swoboda, Vanessa, Schwender, Holger, Lagler, Florian B.
Publicado 2020

Orodispersible minitablets of enalapril for use in children with heart failure (LENA): Rationale and protocol for a multicentre pharmacokinetic bridging study and follow-up safety...

por Bajcetic, Milica, de Wildt, Saskia N., Dalinghaus, Michiel, Breitkreutz, Jörg, Klingmann, Ingrid, Lagler, Florian B., Keatley-Clarke, Anne, Breur, Johannes MPJ., Male, Christoph, Jovanovic, Ida, Szatmári, Andras, Ablonczy, László, Burckhardt, Bjoern B., Cawello, Willi, Kleine, Karl, Obarcanin, Emina, Spatenkova, Lucie, Swoboda, Vanessa, van der Meulen, Marijke, Wagner, Peter, Walsh, Jennifer, Läer, Stephanie
Publicado 2019