MHC Restriction: Where Are We Now?

por Zareie, Pirooz, Farenc, Carine, La Gruta, Nicole L.
Publicado 2020

Hiding in Plain Sight: Virtually Unrecognizable Memory Phenotype CD8(+) T cells

por Thiele, Daniel, La Gruta, Nicole L., Nguyen, Angela, Hussain, Tabinda
Publicado 2020

The clock is ticking: the impact of ageing on T cell metabolism

por Quinn, Kylie M, Palchaudhuri, Riya, Palmer, Clovis S, La Gruta, Nicole L
Publicado 2019

Evaluation of inflammation and follicle depletion during ovarian ageing in mice

por Lliberos, Carolina, Liew, Seng H., Zareie, Pirooz, La Gruta, Nicole L., Mansell, Ashley, Hutt, Karla
Publicado 2021

Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection

por Liu, Haiyin, Jain, Reema, Guan, Jing, Vuong, Vivian, Ishido, Satoshi, La Gruta, Nicole L., Gray, Daniel H., Villadangos, Jose A., Mintern, Justine D.
Publicado 2016

Modified Vaccinia Virus Ankara Can Induce Optimal CD8(+) T Cell Responses to Directly Primed Antigens Depending on Vaccine Design

por Wong, Yik Chun, Croft, Sarah, Smith, Stewart A., Lin, Leon C. W., Cukalac, Tania, La Gruta, Nicole L., Drexler, Ingo, Tscharke, David C.
Publicado 2019

Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus

por Szeto, Christopher, Zareie, Pirooz, Wirasinha, Rushika C., Zhang, Justin B., Nguyen, Andrea T., Riboldi-Tunnicliffe, Alan, La Gruta, Nicole L., Gras, Stephanie, Daley, Stephen R.
Publicado 2022

Protective Efficacy of Cross-Reactive CD8(+) T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

por Valkenburg, Sophie A., Gras, Stephanie, Guillonneau, Carole, La Gruta, Nicole L., Thomas, Paul G., Purcell, Anthony W., Rossjohn, Jamie, Doherty, Peter C., Turner, Stephen J., Kedzierska, Katherine
Publicado 2010

TCR_Explore: A novel webtool for T cell receptor repertoire analysis

por Mullan, Kerry A., Zhang, Justin B., Jones, Claerwen M., Goh, Shawn J.R., Revote, Jerico, Illing, Patricia T., Purcell, Anthony W., La Gruta, Nicole L., Li, Chen, Mifsud, Nicole A.
Publicado 2023

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses

por Wu, Ting, Guan, Jing, Handel, Andreas, Tscharke, David C., Sidney, John, Sette, Alessandro, Wakim, Linda M., Sng, Xavier Y. X., Thomas, Paul G., Croft, Nathan P., Purcell, Anthony W., La Gruta, Nicole L.
Publicado 2019

T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8

por Tran, Mai T., Faridi, Pouya, Lim, Jia Jia, Ting, Yi Tian, Onwukwe, Goodluck, Bhattacharjee, Pushpak, Jones, Claerwen M., Tresoldi, Eleonora, Cameron, Fergus J., La Gruta, Nicole L., Purcell, Anthony W., Mannering, Stuart I., Rossjohn, Jamie, Reid, Hugh H.
Publicado 2021

Most viral peptides displayed by class I MHC on infected cells are immunogenic

por Croft, Nathan P., Smith, Stewart A., Pickering, Jana, Sidney, John, Peters, Bjoern, Faridi, Pouya, Witney, Matthew J., Sebastian, Prince, Flesch, Inge E. A., Heading, Sally L., Sette, Alessandro, La Gruta, Nicole L., Purcell, Anthony W., Tscharke, David C.
Publicado 2019

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude

por Quinn, Kylie M., Kan, Wan-Ting, Watson, Katherine A., Liddicoat, Brian J., Swan, Natasha G., McQuilten, Hayley, Denton, Alice E., Li, Jasmine, Chen, Weisan, Brown, Lorena E., Jackson, David C., Reading, Patrick C., Doherty, Peter C., Kedzierska, Katherine, Kedzierski, Lukasz, Turner, Stephen J., La Gruta, Nicole L.
Publicado 2017

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

por Scally, Stephen W., Petersen, Jan, Law, Soi Cheng, Dudek, Nadine L., Nel, Hendrik J., Loh, Khai Lee, Wijeyewickrema, Lakshmi C., Eckle, Sidonia B.G., van Heemst, Jurgen, Pike, Robert N., McCluskey, James, Toes, Rene E., La Gruta, Nicole L., Purcell, Anthony W., Reid, Hugh H., Thomas, Ranjeny, Rossjohn, Jamie
Publicado 2013

Metabolic characteristics of CD8(+) T cell subsets in young and aged individuals are not predictive of functionality

por Quinn, Kylie M., Hussain, Tabinda, Kraus, Felix, Formosa, Luke E., Lam, Wai K., Dagley, Michael J., Saunders, Eleanor C., Assmus, Lisa M., Wynne-Jones, Erica, Loh, Liyen, van de Sandt, Carolien E., Cooper, Lucy, Good-Jacobson, Kim L., Kedzierska, Katherine, Mackay, Laura K., McConville, Malcolm J., Ramm, Georg, Ryan, Michael T., La Gruta, Nicole L.
Publicado 2020

Publisher Correction: Metabolic characteristics of CD8(+) T cell subsets in young and aged individuals are not predictive of functionality

por Quinn, Kylie M., Hussain, Tabinda, Kraus, Felix, Formosa, Luke E., Lam, Wai K., Dagley, Michael J., Saunders, Eleanor C., Assmus, Lisa M., Wynne-Jones, Erica, Loh, Liyen, van de Sandt, Carolien E., Cooper, Lucy, Good-Jacobson, Kim L., Kedzierska, Katherine, Mackay, Laura K., McConville, Malcolm J., Ramm, Georg, Ryan, Michael T., La Gruta, Nicole L.
Publicado 2020

Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility

por Wirasinha, Rushika C., Davies, Ainsley R., Srivastava, Monika, Sheridan, Julie M., Sng, Xavier Y.X., Delmonte, Ottavia M., Dobbs, Kerry, Loh, Khai L., Miosge, Lisa A., Lee, Cindy Eunhee, Chand, Rochna, Chan, Anna, Yap, Jin Yan, Keller, Michael D., Chen, Karin, Rossjohn, Jamie, La Gruta, Nicole L., Vinuesa, Carola G., Reid, Hugh H., Lionakis, Michail S., Notarangelo, Luigi D., Gray, Daniel H.D., Goodnow, Christopher C., Cook, Matthew C., Daley, Stephen R.
Publicado 2020

Clonally diverse CD38(+)HLA-DR(+)CD8(+) T cells persist during fatal H7N9 disease

por Wang, Zhongfang, Zhu, Lingyan, Nguyen, Thi H. O., Wan, Yanmin, Sant, Sneha, Quiñones-Parra, Sergio M., Crawford, Jeremy Chase, Eltahla, Auda A., Rizzetto, Simone, Bull, Rowena A., Qiu, Chenli, Koutsakos, Marios, Clemens, E. Bridie, Loh, Liyen, Chen, Tianyue, Liu, Lu, Cao, Pengxing, Ren, Yanqin, Kedzierski, Lukasz, Kotsimbos, Tom, McCaw, James M., La Gruta, Nicole L., Turner, Stephen J., Cheng, Allen C., Luciani, Fabio, Zhang, Xiaoyan, Doherty, Peter C., Thomas, Paul G., Xu, Jianqing, Kedzierska, Katherine
Publicado 2018

Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan

por van de Sandt, Carolien E., Nguyen, Thi H. O., Gherardin, Nicholas A., Crawford, Jeremy Chase, Samir, Jerome, Minervina, Anastasia A., Pogorelyy, Mikhail V., Rizzetto, Simone, Szeto, Christopher, Kaur, Jasveen, Ranson, Nicole, Sonda, Sabrina, Harper, Alice, Redmond, Samuel J., McQuilten, Hayley A., Menon, Tejas, Sant, Sneha, Jia, Xiaoxiao, Pedrina, Kate, Karapanagiotidis, Theo, Cain, Natalie, Nicholson, Suellen, Chen, Zhenjun, Lim, Ratana, Clemens, E. Bridie, Eltahla, Auda, La Gruta, Nicole L., Crowe, Jane, Lappas, Martha, Rossjohn, Jamie, Godfrey, Dale I., Thomas, Paul G., Gras, Stephanie, Flanagan, Katie L., Luciani, Fabio, Kedzierska, Katherine
Publicado 2023