Allosteric Communication Networks in Proteins Revealed through Pocket Crosstalk Analysis

por La Sala, Giuseppina, Decherchi, Sergio, De Vivo, Marco, Rocchia, Walter
Publicado 2017

Novel Bacterial Topoisomerase Inhibitors Exploit Asp83 and the Intrinsic Flexibility of the DNA Gyrase Binding Site

por Franco-Ulloa, Sebastian, La Sala, Giuseppina, Miscione, Gian Pietro, De Vivo, Marco
Publicado 2018

Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders

por Savardi, Annalisa, Borgogno, Marco, Narducci, Roberto, La Sala, Giuseppina, Ortega, Jose Antonio, Summa, Maria, Armirotti, Andrea, Bertorelli, Rosalia, Contestabile, Andrea, De Vivo, Marco, Cancedda, Laura
Publicado 2020

Combining structural and coevolution information to unveil allosteric sites

por La Sala, Giuseppina, Pfleger, Christopher, Käck, Helena, Wissler, Lisa, Nevin, Philip, Böhm, Kerstin, Janet, Jon Paul, Schimpl, Marianne, Stubbs, Christopher J., De Vivo, Marco, Tyrchan, Christian, Hogner, Anders, Gohlke, Holger, Frolov, Andrey I.
Publicado 2023

Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance

por Colini Baldeschi, Arianna, Zattoni, Marco, Vanni, Silvia, Nikolic, Lea, Ferracin, Chiara, La Sala, Giuseppina, Summa, Maria, Bertorelli, Rosalia, Bertozzi, Sine Mandrup, Giachin, Gabriele, Carloni, Paolo, Bolognesi, Maria Laura, De Vivo, Marco, Legname, Giuseppe
Publicado 2022

Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein–Protein Interaction

por Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin
Publicado 2022

Correction to “Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein–Protein Interaction”

por Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin
Publicado 2023

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

por Duarte, Daniel P., Lamontanara, Allan J., La Sala, Giuseppina, Jeong, Sukyo, Sohn, Yoo-Kyoung, Panjkovich, Alejandro, Georgeon, Sandrine, Kükenshöner, Tim, Marcaida, Maria J., Pojer, Florence, De Vivo, Marco, Svergun, Dmitri, Kim, Hak-Sung, Dal Peraro, Matteo, Hantschel, Oliver
Publicado 2020

Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer

por Jahid, Sohail, Ortega, Jose A., Vuong, Linh M., Acquistapace, Isabella Maria, Hachey, Stephanie J., Flesher, Jessica L., La Serra, Maria Antonietta, Brindani, Nicoletta, La Sala, Giuseppina, Manigrasso, Jacopo, Arencibia, Jose M., Bertozzi, Sine Mandrup, Summa, Maria, Bertorelli, Rosalia, Armirotti, Andrea, Jin, Rongsheng, Liu, Zheng, Chen, Chi-Fen, Edwards, Robert, Hughes, Christopher C.W., De Vivo, Marco, Ganesan, Anand K.
Publicado 2022