Evaluation of the effects of formulation, food, or a proton-pump inhibitor on the pharmacokinetics of glasdegib (PF-04449913) in healthy volunteers: a randomized phase I study

por Shaik, Naveed, Hee, Brian, Wei, Hua, LaBadie, Robert R.
Publicado 2018

Absolute Oral Bioavailability of Glasdegib (PF‐04449913), a Smoothened Inhibitor, in Randomized Healthy Volunteers

por Shaik, Naveed, Hee, Brian, Liang, Yali, LaBadie, Robert Roland
Publicado 2019

Evaluation of the impact of renal impairment on the pharmacokinetics of glasdegib in otherwise healthy volunteers

por Shaik, Naveed, LaBadie, Robert R., Hee, Brian, Chan, Geoffrey
Publicado 2021

An Eight-Week Trial Investigating the Efficacy and Tolerability of Atorvastatin for Children and Adolescents With Heterozygous Familial Hypercholesterolemia

por Gandelman, Kuan, Glue, Paul, Laskey, Rachel, Jones, Jonathan, LaBadie, Robert, Ose, Leiv
Publicado 2011

Pharmacokinetics and Safety of Glasdegib in Participants With Moderate/Severe Hepatic Impairment: A Phase I, Single‐Dose, Matched Case‐Control Study

por Masters, Joanna C., LaBadie, Robert R., Salageanu, Joanne, Li, Jerry, Shaik, Naveed
Publicado 2020

Clinical and Model‐Based Evaluation of the Effect of Glasdegib on Cardiac Repolarization From a Randomized Thorough QT Study

por Masters, Joanna C., Shaik, Naveed, Mendes da Costa, Laure, Hee, Brian, LaBadie, Robert R.
Publicado 2020

The Effect of Hepatic Impairment on the Pharmacokinetics of Dacomitinib

por Piscitelli, Joseph, Chen, Joseph, LaBadie, Robert R., Salageanu, Joanne, Chung, Chin-Hee, Tan, Weiwei
Publicado 2022

The Effect of Modafinil on the Safety and Pharmacokinetics of Lorlatinib: A Phase I Study in Healthy Participants

por Li, Jerry, Pithavala, Yazdi K., Gong, Jason, LaBadie, Robert R., Mfopou, Josué Kunjom, Chen, Joseph
Publicado 2021

A Thorough QT Study to Evaluate the Effects of a Supratherapeutic Dose of Sertraline on Cardiac Repolarization in Healthy Subjects

por Abbas, Richat, Riley, Steve, LaBadie, Robert R., Bachinsky, Mary, Chappell, Phillip B., Crownover, Penelope H., Damle, Bharat
Publicado 2019

A Phase I Study to Evaluate the Pharmacokinetics and Safety of Lorlatinib in Adults with Mild, Moderate, and Severe Renal Impairment

por Lin, Swan, Gong, Jason, Canas, George C., Winkle, Peter, Pelletier, Kathleen, LaBadie, Robert R., Ginman, Katherine, Pithavala, Yazdi K.
Publicado 2022

Correction to: A Phase I Study to Evaluate the Pharmacokinetics and Safety of Lorlatinib in Adults with Mild, Moderate, and Severe Renal Impairment

por Lin, Swan, Gong, Jason, Canas, George C., Winkle, Peter, Pelletier, Kathleen, LaBadie, Robert R., Ginman, Katherine, Pithavala, Yazdi K.
Publicado 2022

Bioequivalence and Bioavailability of an Orodispersible Tablet of Sildenafil Citrate in Healthy Chinese Male Subjects

por Lv, Yuan, Luo, Bin‐yu, LaBadie, Robert R., Zhu, Hua, Feng, Yan, Ernst, Cynthia, Crownover, Penelope H., Liang, Yali, Zhao, Qinying
Publicado 2020

Influence of mild and moderate hepatic impairment on axitinib pharmacokinetics

por Tortorici, Michael A., Toh, Melvin, Rahavendran, S. V., LaBadie, Robert R., Alvey, Christine W., Marbury, Thomas, Fuentes, Ernesto, Green, Matthew, Ni, Grace, Hee, Brian, Pithavala, Yazdi K.
Publicado 2010

Pharmacokinetics of Oral Nirmatrelvir/Ritonavir, a Protease Inhibitor for Treatment of COVID‐19, in Subjects With Renal Impairment

por Toussi, Sima S., Neutel, Joel Michael, Navarro, Jesus, Preston, Richard Alfred, Shi, Haihong, Kavetska, Olga, LaBadie, Robert R., Binks, Michael, Chan, Phylinda L.S., Demers, Neil, Corrigan, Brian, Damle, Bharat
Publicado 2022