The role of cellular proteostasis in antitumor immunity

por Mercier, Rebecca, LaPointe, Paul
Publicado 2022

A novel method for site-specific chemical SUMOylation: SUMOylation of Hsp90 modulates co-chaperone binding in vitro

por Wolmarans, Annemarie, Kwantes, Allison, LaPointe, Paul
Publicado 2019

Hsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference–mediated silencing in mammalian cells

por Pare, Justin M., LaPointe, Paul, Hobman, Tom C.
Publicado 2013

The Mechanism of Hsp90 ATPase Stimulation by Aha1

por Wolmarans, Annemarie, Lee, Brian, Spyracopoulos, Leo, LaPointe, Paul
Publicado 2016

Hsp90 mutants with distinct defects provide novel insights into cochaperone regulation of the folding cycle

por Mercier, Rebecca, Yama, Danielle, LaPointe, Paul, Johnson, Jill L.
Publicado 2023

A Small Molecule Inhibitor of Pex3–Pex19 Interaction Disrupts Glycosome Biogenesis and Causes Lethality in Trypanosoma brucei

por Banerjee, Hiren, LaPointe, Paul, Eitzen, Gary, Rachubinski, Richard A.
Publicado 2021

The Co-Chaperone Hch1 Regulates Hsp90 Function Differently than Its Homologue Aha1 and Confers Sensitivity to Yeast to the Hsp90 Inhibitor NVP-AUY922

por Armstrong, Heather, Wolmarans, Annemarie, Mercier, Rebecca, Mai, BaoChan, LaPointe, Paul
Publicado 2012

The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation

por Mercier, Rebecca, Wolmarans, Annemarie, Schubert, Jonathan, Neuweiler, Hannes, Johnson, Jill L., LaPointe, Paul
Publicado 2019

A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation

por Schellenberg, Matthew J., Wu, Tao, Ritchie, Dustin B., Fica, Sebastian, Staley, Jonathan P., Atta, Karim A., LaPointe, Paul, MacMillan, Andrew M.
Publicado 2013

Biological and Structural Basis for Aha1 Regulation of Hsp90 ATPase Activity in Maintaining Proteostasis in the Human Disease Cystic Fibrosis

por Koulov, Atanas V., LaPointe, Paul, Lu, Bingwen, Razvi, Abbas, Coppinger, Judith, Dong, Meng-Qiu, Matteson, Jeanne, Laister, Rob, Arrowsmith, Cheryl, Yates, John R., Balch, William E.
Publicado 2010

An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans

por Zuehlke, Abbey D., Reidy, Michael, Lin, Coney, LaPointe, Paul, Alsomairy, Sarah, Lee, D. Joshua, Rivera-Marquez, Genesis M., Beebe, Kristin, Prince, Thomas, Lee, Sunmin, Trepel, Jane B., Xu, Wanping, Johnson, Jill, Masison, Daniel, Neckers, Len
Publicado 2017

Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8–9, 2022

por van Oosten-Hawle, Patricija, Backe, Sarah J., Ben-Zvi, Anat, Bourboulia, Dimitra, Brancaccio, Mara, Brodsky, Jeff, Clark, Melody, Colombo, Giorgio, Cox, Marc B., De Los Rios, Paolo, Echtenkamp, Frank, Edkins, Adrienne, Freeman, Brian, Goloubinoff, Pierre, Houry, Walid, Johnson, Jill, LaPointe, Paul, Li, Wei, Mezger, Valerie, Neckers, Len, Nillegoda, Nadinath B., Prahlad, Veena, Reitzel, Adam, Scherz-Shouval, Ruth, Sistonen, Lea, Tsai, Francis T. F., Woodford, Mark R., Mollapour, Mehdi, Truman, Andrew W.
Publicado 2023