Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection

por Johnson, Anders F., Sands, Jenna S., Trivedi, Keya M., Russell, Raedeen, LaRock, Doris L., LaRock, Christopher N.
Publicado 2023

Yersinia pestis insecticidal-like toxin complex (Tc) family proteins: characterization of expression, subcellular localization, and potential role in infection of the flea vector

por Spinner, Justin L, Jarrett, Clayton O, LaRock, Doris L, Miller, Samuel I, Collins, Carleen M, Hinnebusch, B Joseph
Publicado 2012

Inflammasome inhibition blocks cardiac glycoside cell toxicity

por LaRock, Doris L., Sands, Jenna S., Ettouati, Ethan, Richard, Marine, Bushway, Paul J., Adler, Eric D., Nizet, Victor, LaRock, Christopher N.
Publicado 2019

The Pseudomonas aeruginosa protease LasB directly activates IL-1β

por Sun, Josh, LaRock, Doris L., Skowronski, Elaine A., Kimmey, Jacqueline M., Olson, Joshua, Jiang, Zhenze, O'Donoghue, Anthony J., Nizet, Victor, LaRock, Christopher N.
Publicado 2020

Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models

por Everett, Martin J., Davies, David T., Leiris, Simon, Sprynski, Nicolas, Llanos, Agustina, Castandet, Jérôme M., Lozano, Clarisse, LaRock, Christopher N., LaRock, Doris L., Corsica, Giuseppina, Docquier, Jean-Denis, Pallin, Thomas D., Cridland, Andrew, Blench, Toby, Zalacain, Magdalena, Lemonnier, Marc
Publicado 2023