Think big, start small, move fast: a blueprint for transformation from the Mayo Clinic Center for Innovation

por LaRusso, Nicholas, Spurrier, Barbara, Farrugia, Gianrico
Publicado 2015

Cholangiocytes and the environment in primary sclerosing cholangitis: where is the link?

por O’Hara, Steven P, Karlsen, Tom H, LaRusso, Nicholas F
Publicado 2017

Epidermal Growth Factor Protects the Apical Junctional Complexes from Hydrogen peroxide in Bile Duct Epithelium

por Guntaka, Srikar R., Samak, Geetha, Seth, Ankur, LaRusso, Nicholas F., Rao, Radhakrishna
Publicado 2011

MicroRNAs in the Cholangiopathies: Pathogenesis, Diagnosis, and Treatment

por Lorenzo Pisarello, Maria Jose, Loarca, Lorena, Ivanics, Tommy, Morton, Leslie, LaRusso, Nicholas
Publicado 2015

Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B

por Gradilone, Sergio A, Tietz, Pamela S, Splinter, Patrick L, Marinelli, Raúl A, LaRusso, Nicholas F
Publicado 2005

Autophagy-mediated reduction of miR-345 contributes to hepatic cystogenesis in polycystic liver disease

por Masyuk, Tatyana, Masyuk, Anatoliy, Trussoni, Christy, Howard, Brynn, Ding, Jingyi, Huang, Bing, LaRusso, Nicholas
Publicado 2021

Genetic or pharmacological reduction of cholangiocyte senescence improves inflammation and fibrosis in the Mdr2(-/-) mouse

por Alsuraih, Mohammed, O’Hara, Steven P., Woodrum, Julie E., Pirius, Nicholas E., LaRusso, Nicholas F.
Publicado 2021

If you feed them, they will come: A prospective study of the effects of complimentary food on attendance and physician attitudes at medical grand rounds at an academic medical cent...

por Segovis, Colin M, Mueller, Paul S, Rethlefsen, Melissa L, LaRusso, Nicholas F, Litin, Scott C, Tefferi, Ayalew, Habermann, Thomas M
Publicado 2007

Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis

por Tabibian, James H., Trussoni, Christy E., O’Hara, Steven P., Splinter, Patrick L., Heimbach, Julie K., LaRusso, Nicholas F.
Publicado 2014

Polarized human cholangiocytes release distinct populations of apical and basolateral small extracellular vesicles

por Davies, Brian A., Morton, Leslie O., Jefferson, John R., Rozeveld, Cody N., Doskey, Luke C., LaRusso, Nicholas F., Katzmann, David J.
Publicado 2020

Release of Luminal Exosomes Contributes to TLR4-Mediated Epithelial Antimicrobial Defense

por Hu, Guoku, Gong, Ai-Yu, Roth, Amanda L., Huang, Bing Q., Ward, Honorine D., Zhu, Guan, LaRusso, Nicholas F., Hanson, Nancy D., Chen, Xian-Ming
Publicado 2013

Metabolomic Profiling of Portal Blood and Bile Reveals Metabolic Signatures of Primary Sclerosing Cholangitis

por Tietz-Bogert, Pamela S., Kim, Minsuk, Cheung, Angela, Tabibian, James H., Heimbach, Julie K., Rosen, Charles B., Nandakumar, Madhumitha, Lazaridis, Konstantinos N., LaRusso, Nicholas F., Sung, Jaeyun, O’Hara, Steven P.
Publicado 2018

High‐Resolution Exposomics and Metabolomics Reveals Specific Associations in Cholestatic Liver Diseases

por Walker, Douglas I., Juran, Brian D., Cheung, Angela C., Schlicht, Erik M., Liang, Yongliang, Niedzwiecki, Megan, LaRusso, Nicholas F., Gores, Gregory J., Jones, Dean P., Miller, Gary W., Lazaridis, Konstantinos N.
Publicado 2021

Serum miRNA profiles are altered in patients with primary sclerosing cholangitis receiving high-dose ursodeoxycholic acid

por Hochberg, Jessica T., Sohal, Aalam, Handa, Priya, Maliken, Bryan D., Kim, Take-Kyun, Wang, Kai, Gochanour, Eric, Li, Yu, Rose, J. Bart, Nelson, James E., Lindor, Keith D., LaRusso, Nicholas F., Kowdley, Kris V.
Publicado 2023

Role for Krüppel-Like Transcription Factor 11 in Mesenchymal Cell Function and Fibrosis

por Mathison, Angela, Grzenda, Adrienne, Lomberk, Gwen, Velez, Gabriel, Buttar, Navtej, Tietz, Pamela, Hendrickson, Helen, Liebl, Ann, Xiong, Yuning Y., Gores, Gregory, Fernandez-Zapico, Martin, LaRusso, Nicholas F., Faubion, William, Shah, Vijay H., Urrutia, Raul
Publicado 2013

Ileo-colonic delivery of conjugated bile acids improves glucose homeostasis via colonic GLP-1-producing enteroendocrine cells in human obesity and diabetes

por Calderon, Gerardo, McRae, Alison, Rievaj, Juraj, Davis, Judith, Zandvakili, Inuk, Linker-Nord, Sara, Burton, Duane, Roberts, Geoffrey, Reimann, Frank, Gedulin, Bronislava, Vella, Adrian, LaRusso, Nicholas F, Camilleri, Michael, Gribble, Fiona M, Acosta, Andres
Publicado 2020

DNA methylation profile of liver tissue in end-stage cholestatic liver disease

por Cheung, Angela C, Juran, Brian D, Schlicht, Erik M, McCauley, Bryan M, Atkinson, Elizabeth J, Moore, Raymond, Heimbach, Julie K, Watt, Kymberly D, Wu, Tsung-Teh, LaRusso, Nicholas F, Gores, Gregory J, Sun, Zhifu, Lazaridis, Konstantinos N
Publicado 2022

A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis

por Kowdley, Kris V., Vuppalanchi, Raj, Levy, Cynthia, Floreani, Annarosa, Andreone, Pietro, LaRusso, Nicholas F., Shrestha, Roshan, Trotter, James, Goldberg, David, Rushbrook, Simon, Hirschfield, Gideon M., Schiano, Thomas, jin, Yuying, Pencek, Richard, MacConell, Leigh, Shapiro, David, Bowlus, Christopher L.
Publicado 2020

Development and Characterization of Cholangioids from Normal and Diseased Human Cholangiocytes as an In Vitro Model to Study Primary Sclerosing Cholangitis

por Loarca, Lorena, De Assuncao, Thiago M., Jalan-Sakrikar, Nidhi, Bronk, Steve, Krishan, Anuradha, Huang, Bing, Morton, Leslie, Trussoni, Christy, Bonilla, Lorena Marcano, Krueger, Eugene, O’Hara, Steve, Splinter, Patrick, Shi, Guang, Pisarello, María José Lorenzo, Gores, Gregory J., Huebert, Robert C., LaRusso, Nicholas F.
Publicado 2017

Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models

por Lee-Law, Pui Y., Olaizola, Paula, Caballero-Camino, Francisco J., Izquierdo-Sanchez, Laura, Rodrigues, Pedro M., Santos-Laso, Alvaro, Azkargorta, Mikel, Elortza, Felix, Martinez-Chanta, Maria L., Perugorria, Maria J., Aspichueta, Patricia, Marzioni, Marco, LaRusso, Nicholas F., Bujanda, Luis, Drenth, Joost P.H., Banales, Jesus M.
Publicado 2020