Is there a special relationship between complex I activity and nigral neuronal loss in Parkinson’s disease? A critical reappraisal

por Subrahmanian, Nitya, LaVoie, Matthew J.
Publicado 2021

Recognizing the cooperative and independent mitochondrial functions of Parkin and PINK1

por Johnson, Bethann N., Charan, Rakshita A., LaVoie, Matthew J.
Publicado 2012

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

por Ashrafi, Ghazaleh, Schlehe, Julia S., LaVoie, Matthew J., Schwarz, Thomas L.
Publicado 2014

LRRK2 Kinase Inhibition Rescues Deficits in Lysosome Function Due to Heterozygous GBA1 Expression in Human iPSC-Derived Neurons

por Sanyal, Anwesha, Novis, Hailey S., Gasser, Emile, Lin, Steven, LaVoie, Matthew J.
Publicado 2020

Aph-1 Associates Directly with Full-length and C-terminal Fragments of γ-Secretase Substrates

por Chen, Allen C., Guo, Lucie Y., Ostaszewski, Beth L., Selkoe, Dennis J., LaVoie, Matthew J.
Publicado 2010

The Vfl1 Protein in Chlamydomonas Localizes in a Rotationally Asymmetric Pattern at the Distal Ends of the Basal Bodies

por Silflow, Carolyn D., LaVoie, Matthew, Tam, Lai-Wa, Tousey, Susan, Sanders, Mark, Wu, Wei-chien, Borodovsky, Mark, Lefebvre, Paul A.
Publicado 2001

The LRRK2 kinase substrates Rab8a and Rab10 contribute complementary but distinct disease-relevant phenotypes in human neurons

por Mamais, Adamantios, Sanyal, Anwesha, Fajfer, Austin, Zykoski, Catherine G., Guldin, Michael, Riley-DiPaolo, Alexis, Subrahmanian, Nitya, Gibbs, Whitney, Lin, Steven, LaVoie, Matthew J.
Publicado 2023

Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

por Mamais, Adamantios, Kluss, Jillian H., Bonet-Ponce, Luis, Landeck, Natalie, Langston, Rebekah G., Smith, Nathan, Beilina, Alexandra, Kaganovich, Alice, Ghosh, Manik C., Pellegrini, Laura, Kumaran, Ravindran, Papazoglou, Ioannis, Heaton, George R., Bandopadhyay, Rina, Maio, Nunziata, Kim, Changyoun, LaVoie, Matthew J., Gershlick, David C., Cookson, Mark R.
Publicado 2021

Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

por Mamais, Adamantios, Kluss, Jillian H., Bonet-Ponce, Luis, Landeck, Natalie, Langston, Rebekah G., Smith, Nathan, Beilina, Alexandra, Kaganovich, Alice, Ghosh, Manik C., Pellegrini, Laura, Kumaran, Ravindran, Papazoglou, Ioannis, Heaton, George R., Harvey, Kirsten, Bandopadhyay, Rina, Maio, Nunziata, Kim, Changyoun, LaVoie, Matthew J., Gershlick, David C., Cookson, Mark R.
Publicado 2022

Parkin coregulates glutathione metabolism in adult mammalian brain

por El Kodsi, Daniel N., Tokarew, Jacqueline M., Sengupta, Rajib, Lengacher, Nathalie A., Chatterji, Ajanta, Nguyen, Angela P., Boston, Heather, Jiang, Qiubo, Palmberg, Carina, Pileggi, Chantal, Holterman, Chet E., Shutinoski, Bojan, Li, Juan, Fehr, Travis K., LaVoie, Matthew J., Ratan, Rajiv R., Shaw, Gary S., Takanashi, Masashi, Hattori, Nobutaka, Kennedy, Christopher R., Harper, Mary-Ellen, Holmgren, Arne, Tomlinson, Julianna J., Schlossmacher, Michael G.
Publicado 2023