Role of VEGFs/VEGFR-1 Signaling and Its Inhibition in Modulating Tumor Invasion: Experimental Evidence in Different Metastatic Cancer Models

por Ceci, Claudia, Atzori, Maria Grazia, Lacal, Pedro Miguel, Graziani, Grazia
Publicado 2020

Approaching coronavirus disease 2019: Mechanisms of action of repurposed drugs with potential activity against SARS-CoV-2

por Lisi, Lucia, Lacal, Pedro Miguel, Barbaccia, Maria Luisa, Graziani, Grazia
Publicado 2020

Targeting Tumor-Associated Macrophages to Increase the Efficacy of Immune Checkpoint Inhibitors: A Glimpse into Novel Therapeutic Approaches for Metastatic Melanoma

por Ceci, Claudia, Atzori, Maria Grazia, Lacal, Pedro Miguel, Graziani, Grazia
Publicado 2020

The Anti-Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1) D16F7 Monoclonal Antibody Inhibits Melanoma Adhesion to Soluble VEGFR-1 and Tissue Invasion in Response to Placenta...

por Atzori, Maria Grazia, Ceci, Claudia, Ruffini, Federica, Scimeca, Manuel, Cicconi, Rosella, Mattei, Maurizio, Lacal, Pedro Miguel, Graziani, Grazia
Publicado 2022

PDIA3 Expression in Glioblastoma Modulates Macrophage/Microglia Pro-Tumor Activation

por Chiavari, Marta, Ciotti, Gabriella Maria Pia, Canonico, Francesco, Altieri, Fabio, Lacal, Pedro Miguel, Graziani, Grazia, Navarra, Pierluigi, Lisi, Lucia
Publicado 2020

Neuropilin‐1 is required for endothelial cell adhesion to soluble vascular endothelial growth factor receptor 1

por Colotti, Gianni, Failla, Cristina Maria, Lacal, Pedro Miguel, Ungarelli, Mariangela, Ruffini, Federica, Di Micco, Patrizio, Orecchia, Angela, Morea, Veronica
Publicado 2021

Role of VEGFR‐1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

por Atzori, Maria Grazia, Ceci, Claudia, Ruffini, Federica, Trapani, Mauro, Barbaccia, Maria Luisa, Tentori, Lucio, D'Atri, Stefania, Lacal, Pedro Miguel, Graziani, Grazia
Publicado 2019

Multiple Sclerosis Treatment and Melanoma Development

por Carbone, Maria Luigia, Lacal, Pedro Miguel, Messinese, Serena, De Giglio, Laura, Pozzilli, Carlo, Persechino, Severino, Mazzanti, Cinzia, Failla, Cristina Maria, Pagnanelli, Gianluca
Publicado 2020

Targeting the PTTG1 oncogene impairs proliferation and invasiveness of melanoma cells sensitive or with acquired resistance to the BRAF inhibitor dabrafenib

por Caporali, Simona, Alvino, Ester, Lacal, Pedro Miguel, Ruffini, Federica, Levati, Lauretta, Bonmassar, Laura, Scoppola, Alessandro, Marchetti, Paolo, Mastroeni, Simona, Antonini Cappellini, Gian Carlo, D’Atri, Stefania
Publicado 2017

Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by i...

por Caporali, Simona, Alvino, Ester, Amaro, Adriana, Lacal, Pedro Miguel, Levati, Lauretta, Atzori, Maria Grazia, Cappellini, Gian Carlo Antonini, Ruffini, Federica, Bonmassar, Enzo, Pfeffer, Ulrich, D’Atri, Stefania
Publicado 2015

miR-126-3p down-regulation contributes to dabrafenib acquired resistance in melanoma by up-regulating ADAM9 and VEGF-A

por Caporali, Simona, Amaro, Adriana, Levati, Lauretta, Alvino, Ester, Lacal, Pedro Miguel, Mastroeni, Simona, Ruffini, Federica, Bonmassar, Laura, Antonini Cappellini, Gian Carlo, Felli, Nadia, Carè, Alessandra, Pfeffer, Ulrich, D’Atri, Stefania
Publicado 2019

A novel and atypical NF-KB pro-inflammatory program regulated by a CamKII-proteasome axis is involved in the early activation of Muller glia by high glucose

por Sbardella, Diego, Tundo, Grazia Raffaella, Mecchia, Alice, Palumbo, Camilla, Atzori, Maria Grazia, Levati, Lauretta, Boccaccini, Alessandra, Caccuri, Anna Maria, Cascio, Paolo, Lacal, Pedro Miguel, Graziani, Grazia, Varano, Monica, Coletta, Massimiliano, Parravano, Mariacristina
Publicado 2022

VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody

por Micheli, Laura, Parisio, Carmen, Lucarini, Elena, Vona, Alessia, Toti, Alessandra, Pacini, Alessandra, Mello, Tommaso, Boccella, Serena, Ricciardi, Flavia, Maione, Sabatino, Graziani, Grazia, Lacal, Pedro Miguel, Failli, Paola, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo
Publicado 2021

Circulating miR-1246 and miR-485-3p as Promising Biomarkers of Clinical Response and Outcome in Melanoma Patients Treated with Targeted Therapy

por Levati, Lauretta, Bassi, Cristian, Mastroeni, Simona, Lupini, Laura, Antonini Cappellini, Gian Carlo, Bonmassar, Laura, Alvino, Ester, Caporali, Simona, Lacal, Pedro Miguel, Narducci, Maria Grazia, Molineris, Ivan, De Galitiis, Federica, Negrini, Massimo, Russo, Giandomenico, D’Atri, Stefania
Publicado 2022

The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells

por Atzori, Maria Grazia, Tentori, Lucio, Ruffini, Federica, Ceci, Claudia, Lisi, Lucia, Bonanno, Elena, Scimeca, Manuel, Eskilsson, Eskil, Daubon, Thomas, Miletic, Hrvoje, Ricci Vitiani, Lucia, Pallini, Roberto, Navarra, Pierluigi, Bjerkvig, Rolf, D’Atri, Stefania, Lacal, Pedro Miguel, Graziani, Grazia
Publicado 2017