Recombinant Modified Vaccinia Virus Ankara (MVA) Expressing Wild-Type Human p53 Induces Specific Antitumor CTL Expansion

por Song, Guang-Yun, Srivastava, Tumul, Ishizaki, Hidenobu, Lacey, Simon F., Diamond, Don J., Ellenhorn, Joshua D. I.
Publicado 2011

Establishing a model system for evaluating CAR T cell therapy using dogs with spontaneous diffuse large B cell lymphoma

por Panjwani, M. Kazim, Atherton, Matthew J., MaloneyHuss, Martha A., Haran, Kumudhini P., Xiong, Ailian, Gupta, Minnal, Kulikovsaya, Irina, Lacey, Simon F., Mason, Nicola J.
Publicado 2019

PD1 Expression in EGFRvIII-Directed CAR T Cell Infusion Product for Glioblastoma Is Associated with Clinical Response

por Tang, Oliver Y., Tian, Lifeng, Yoder, Todd, Xu, Rong, Kulikovskaya, Irina, Gupta, Minnal, Melenhorst, Jan Joseph, Lacey, Simon F., O’Rourke, Donald M., Binder, Zev A.
Publicado 2022

Endothelial Biomarkers Are Associated With Indirect Lung Injury in Sepsis-Associated Pediatric Acute Respiratory Distress Syndrome

por Whitney, Jane E., Feng, Rui, Koterba, Natalka, Chen, Fang, Bush, Jenny, Graham, Kathryn, Lacey, Simon F., Melenhorst, Jan Joseph, Parikh, Samir M., Weiss, Scott L., Yehya, Nadir
Publicado 2020

CAR T Cell Therapy of Non-hematopoietic Malignancies: Detours on the Road to Clinical Success

por Long, Kristen B., Young, Regina M., Boesteanu, Alina C., Davis, Megan M., Melenhorst, J. Joseph, Lacey, Simon F., DeGaramo, David A., Levine, Bruce L., Fraietta, Joseph A.
Publicado 2018

Treatment of leukemia antigen-loss relapses occurring after CD19-targeted immunotherapies by combination of anti-CD123 and anti-CD19 chimeric antigen receptor T cells

por Ruella, Marco, Barrett, David M, Kenderian, Saad S, Shestova, Olga, Hofmann, Ted J, Scholler, John, Lacey, Simon F, Melenhorst, Jan J, Nazimuddin, Farzana, Perazzelli, Jessica, Christian, David A, Hunter, Christopher A, Porter, David L, June, Carl H, Grupp, Stephan A, Gill, Saar
Publicado 2015

Case Report: Prolonged Survival Following EGFRvIII CAR T Cell Treatment for Recurrent Glioblastoma

por Durgin, Joseph S., Henderson, Fraser, Nasrallah, MacLean P., Mohan, Suyash, Wang, Sumei, Lacey, Simon F., Melenhorst, Jan Joseph, Desai, Arati S., Lee, John Y. K., Maus, Marcela V., June, Carl H., Brem, Steven, O’Connor, Roddy S., Binder, Zev, O’Rourke, Donald M.
Publicado 2021

Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor

por Leibman, Rachel S., Richardson, Max W., Ellebrecht, Christoph T., Maldini, Colby R., Glover, Joshua A., Secreto, Anthony J., Kulikovskaya, Irina, Lacey, Simon F., Akkina, Sarah R., Yi, Yanjie, Shaheen, Farida, Wang, Jianbin, Dufendach, Keith A., Holmes, Michael C., Collman, Ronald G., Payne, Aimee S., Riley, James L.
Publicado 2017

Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma

por Bajor, David L., Mick, Rosemarie, Riese, Matthew J., Huang, Alex C., Sullivan, Brendan, Richman, Lee P., Torigian, Drew A., George, Sangeeth M., Stelekati, Erietta, Chen, Fang, Melenhorst, J. Joseph, Lacey, Simon F., Xu, Xiaowei, Wherry, E. John, Gangadhar, Tara C., Amaravadi, Ravi K., Schuchter, Lynn M., Vonderheide, Robert H.
Publicado 2018

BLIMP1 and NR4A3 Transcription Factors Reciprocally Regulate Antitumor CAR T-cell Stemness and Exhaustion

por Jung, In-Young, Narayan, Vivek, McDonald, Sierra, Rech, Andrew J., Bartoszek, Robert, Hong, Gwanui, Davis, Megan M., Xu, Jun, Boesteanu, Alina C., Barber-Rotenberg, Julie S., Plesa, Gabriela, Lacey, Simon F., Jadlowsky, Julie K., Siegel, Donald L., Hammill, Dana M., Cho-Park, Park F., Berger, Shelley L., Haas, Naomi B., Fraietta, Joseph A.
Publicado 2022

Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

por Shah, Payal D., Huang, Alexander C., Xu, Xiaowei, Orlowski, Robert, Amaravadi, Ravi K., Schuchter, Lynn M., Zhang, Paul, Tchou, Julia, Matlawski, Tina, Cervini, Amanda, Shea, Joanne, Gilmore, Joan, Lledo, Lester, Dengel, Karen, Marshall, Amy, Wherry, E. John, Linette, Gerald P., Brennan, Andrea, Gonzalez, Vanessa, Kulikovskaya, Irina, Lacey, Simon F., Plesa, Gabriela, June, Carl H., Vonderheide, Robert H., Mitchell, Tara C.
Publicado 2023

Anti-CD19 CAR T cells in combination with ibrutinib for the treatment of chronic lymphocytic leukemia

por Gill, Saar, Vides, Vanessa, Frey, Noelle V., Hexner, Elizabeth O., Metzger, Susan, O'Brien, Megan, Hwang, Wei-Ting, Brogdon, Jennifer L., Davis, Megan M., Fraietta, Joseph A., Gaymon, Avery L., Gladney, Whitney L., Lacey, Simon F., Lamontagne, Anne, Mato, Anthony R., Maus, Marcela V., Melenhorst, J. Joseph, Pequignot, Edward, Ruella, Marco, Shestov, Maksim, Byrd, John C., Schuster, Stephen J., Siegel, Donald L., Levine, Bruce L., June, Carl H., Porter, David L.
Publicado 2022

NY-ESO-1 specific TCR engineered T-cells mediate sustained antigen-specific antitumor effects in myeloma

por Rapoport, Aaron P., Stadtmauer, Edward A., Binder-Scholl, Gwendolyn K., Goloubeva, Olga, Vogl, Dan T., Lacey, Simon F., Badros, Ashraf Z., Garfall, Alfred, Weiss, Brendan, Finklestein, Jeffrey, Kulikovskaya, Irina, Sinha, Sanjoy K., Kronsberg, Shari, Gupta, Minnal, Bond, Sarah, Melchiori, Luca, Brewer, Joanna E., Bennett, Alan D., Gerry, Andrew B., Pumphrey, Nicholas J., Williams, Daniel, Tayton-Martin, Helen K., Ribeiro, Lilliam, Holdich, Tom, Yanovich, Saul, Hardy, Nancy, Yared, Jean, Kerr, Naseem, Philip, Sunita, Westphal, Sandra, Siegel, Don L., Levine, Bruce L., Jakobsen, Bent K., Kalos, Michael, June, Carl H.
Publicado 2015

Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions

por Mathew, Divij, Giles, Josephine R., Baxter, Amy E., Greenplate, Allison R., Wu, Jennifer E., Alanio, Cécile, Oldridge, Derek A., Kuri-Cervantes, Leticia, Pampena, M. Betina, D’Andrea, Kurt, Manne, Sasikanth, Chen, Zeyu, Huang, Yinghui Jane, Reilly, John P., Weisman, Ariel R, Ittner, Caroline A.G., Kuthuru, Oliva, Dougherty, Jeanette, Nzingha, Kito, Han, Nicholas, Kim, Justin, Pattekar, Ajinkya, Goodwin, Eileen C., Anderson, Elizabeth M., Weirick, Madison E., Gouma, Sigrid, Arevalo, Claudia P., Bolton, Marcus J., Chen, Fang, Lacey, Simon F., Hensley, Scott E., Apostolidis, Sokratis, Huang, Alexander C., Vella, Laura A., Betts, Michael R., Meyer, Nuala J., Wherry, E. John
Publicado 2020

Anti-BCMA/CD19 CAR T Cells with Early Immunomodulatory Maintenance for Multiple Myeloma Responding to Initial or Later-Line Therapy

por Garfall, Alfred L., Cohen, Adam D., Susanibar-Adaniya, Sandra P., Hwang, Wei-Ting, Vogl, Dan T., Waxman, Adam J., Lacey, Simon F., Gonzalez, Vanessa E., Fraietta, Joseph A., Gupta, Minnal, Kulikovskaya, Irina, Tian, Lifeng, Chen, Fang, Koterba, Natalka, Bartoszek, Robert L., Patchin, Margaret, Xu, Rong, Plesa, Gabriela, Siegel, Don L., Brennan, Andrea, Nelson, Anne Marie, Ferthio, Regina, Cosey, Angela, Shea, Kim-Marie, Leskowitz, Rachel, Four, Megan, Wilson, Wesley V., Miao, Fei, Lancaster, Eric, Carreno, Beatriz M., Linette, Gerald P., Hexner, Elizabeth O., Young, Regina M., Bu, Dexiu, Mansfield, Keith G., Brogdon, Jennifer L., June, Carl H., Milone, Michael C., Stadtmauer, Edward A.
Publicado 2023

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

por Mathew, Divij, Giles, Josephine R., Baxter, Amy E., Oldridge, Derek A., Greenplate, Allison R., Wu, Jennifer E., Alanio, Cécile, Kuri-Cervantes, Leticia, Pampena, M. Betina, D’Andrea, Kurt, Manne, Sasikanth, Chen, Zeyu, Huang, Yinghui Jane, Reilly, John P., Weisman, Ariel R., Ittner, Caroline A. G., Kuthuru, Oliva, Dougherty, Jeanette, Nzingha, Kito, Han, Nicholas, Kim, Justin, Pattekar, Ajinkya, Goodwin, Eileen C., Anderson, Elizabeth M., Weirick, Madison E., Gouma, Sigrid, Arevalo, Claudia P., Bolton, Marcus J., Chen, Fang, Lacey, Simon F., Ramage, Holly, Cherry, Sara, Hensley, Scott E., Apostolidis, Sokratis A., Huang, Alexander C., Vella, Laura A., Betts, Michael R., Meyer, Nuala J., Wherry, E. John
Publicado 2020