Proteomics Insights Into the Molecular Basis of SARS-CoV-2 Infection: What We Can Learn From the Human Olfactory Axis

por Lachén-Montes, Mercedes, Corrales, Fernando J., Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2020

Tackling the Biological Meaning of the Human Olfactory Bulb Dyshomeostatic Proteome across Neurological Disorders: An Integrative Bioinformatic Approach

por Cartas-Cejudo, Paz, Lachén-Montes, Mercedes, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2021

Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies

por Lachen-Montes, Mercedes, Zelaya, María Victoria, Segura, Víctor, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2017

Sex-divergent effects on the NAD+-dependent deacetylase sirtuin signaling across the olfactory–entorhinal–amygdaloid axis in Alzheimer’s and Parkinson’s diseases

por Cartas-Cejudo, Paz, Lachén-Montes, Mercedes, Ferrer, Isidro, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2023

Olfactory Bulb Proteomics Reveals Widespread Proteostatic Disturbances in Mixed Dementia and Guides for Potential Serum Biomarkers to Discriminate Alzheimer Disease and Mixed Demen...

por Lachén-Montes, Mercedes, Íñigo-Marco, Ignacio, Cartas-Cejudo, Paz, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2021

Proteomic Characterization of the Olfactory Molecular Imbalance in Dementia with Lewy Bodies

por Lachén-Montes, Mercedes, Mendizuri, Naroa, Schvartz, Domitille, Fernández-Irigoyen, Joaquín, Sánchez, Jean Charles, Santamaría, Enrique
Publicado 2020

Amyotrophic Lateral Sclerosis Is Accompanied by Protein Derangements in the Olfactory Bulb-Tract Axis

por Lachén-Montes, Mercedes, Mendizuri, Naroa, Ausin, Karina, Andrés-Benito, Pol, Ferrer, Isidro, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2020

Network-Driven Proteogenomics Unveils an Aging-Related Imbalance in the Olfactory IκBα-NFκB p65 Complex Functionality in Tg2576 Alzheimer’s Disease Mouse Model

por Palomino-Alonso, Maialen, Lachén-Montes, Mercedes, González-Morales, Andrea, Ausín, Karina, Pérez-Mediavilla, Alberto, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2017

Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer’s disease progression

por Lachén-Montes, Mercedes, González-Morales, Andrea, Zelaya, María Victoria, Pérez-Valderrama, Estela, Ausín, Karina, Ferrer, Isidro, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2017

Neuroanatomical Quantitative Proteomics Reveals Common Pathogenic Biological Routes between Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

por Iridoy, Marina Oaia, Zubiri, Irene, Zelaya, María Victoria, Martinez, Leyre, Ausín, Karina, Lachen-Montes, Mercedes, Santamaría, Enrique, Fernandez-Irigoyen, Joaquín, Jericó, Ivonne
Publicado 2018

Dysregulated Brain Protein Phosphorylation Linked to Increased Human Tau Expression in the hTau Transgenic Mouse Model

por Ferrer, Isidro, Andrés-Benito, Pol, Ausín, Karina, Cartas-Cejudo, Paz, Lachén-Montes, Mercedes, del Rio, José Antonio, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2022

Metabolic dyshomeostasis induced by SARS-CoV-2 structural proteins reveals immunological insights into viral olfactory interactions

por Lachén-Montes, Mercedes, Mendizuri, Naroa, Ausín, Karina, Echaide, Miriam, Blanco, Ester, Chocarro, Luisa, de Toro, María, Escors, David, Fernández-Irigoyen, Joaquín, Kochan, Grazyna, Santamaría, Enrique
Publicado 2022

Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer’s Disease

por Lachen-Montes, Mercedes, González-Morales, Andrea, Palomino, Maialen, Ausin, Karina, Gómez-Ochoa, Marta, Zelaya, María Victoria, Ferrer, Isidro, Pérez-Mediavilla, Alberto, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2019

Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy

por Ferrer, Isidro, Andrés-Benito, Pol, Zelaya, Maria Victoria, Aguirre, Maria Elena Erro, Carmona, Margarita, Ausín, Karina, Lachén-Montes, Mercedes, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, del Rio, José Antonio
Publicado 2020

Deregulated Transcription and Proteostasis in Adult mapt Knockout Mouse

por Andrés-Benito, Pol, Flores, África, Busquet-Areny, Sara, Carmona, Margarita, Ausín, Karina, Cartas-Cejudo, Paz, Lachén-Montes, Mercedes, Del Rio, José Antonio, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, Ferrer, Isidro
Publicado 2023

Cannabis Use Induces Distinctive Proteomic Alterations in Olfactory Neuroepithelial Cells of Schizophrenia Patients

por Barrera-Conde, Marta, Ausin, Karina, Lachén-Montes, Mercedes, Fernández-Irigoyen, Joaquín, Galindo, Liliana, Cuenca-Royo, Aida, Fernández-Avilés, Cristina, Pérez, Víctor, de la Torre, Rafael, Santamaría, Enrique, Robledo, Patricia
Publicado 2021

Amyloid-Driven Tau Accumulation on Mitochondria Potentially Leads to Cognitive Deterioration in Alzheimer’s Disease

por Cuadrado-Tejedor, Mar, Pérez-González, Marta, Alfaro-Ruiz, Rocío, Badesso, Sara, Sucunza, Diego, Espelosin, María, Ursúa, Susana, Lachen-Montes, Mercedes, Fernández-Irigoyen, Joaquín, Santamaria, Enrique, Luján, Rafael, García-Osta, Ana
Publicado 2021

Olfactory Characterization and Training in Older Adults: Protocol Study

por Zambom-Ferraresi, Fabíola, Zambom-Ferraresi, Fabricio, Fernández-Irigoyen, Joaquín, Lachén-Montes, Mercedes, Cartas-Cejudo, Paz, Lasarte, Juan José, Casares, Noelia, Fernández, Secundino, Cedeño-Veloz, Bernardo Abel, Maraví-Aznar, Enrique, Uzcanga-Lacabe, Maria Itziar, Galbete, Arkaitz, Santamaría, Enrique, Martínez-Velilla, Nicolás
Publicado 2021