Neurons Derived From Patient-Specific Induced Pluripotent Stem Cells: a Promising Strategy Towards Developing Novel Pharmacotherapies for Autism Spectrum Disorders

por Mokhtari, Ryan, Lachman, Herbert M.
Publicado 2016

The Major Histocompatibility Complex (MHC) in Schizophrenia: A Review

por Mokhtari, Ryan, Lachman, Herbert M
Publicado 2016

Characterization of cell-cell communication in autistic brains with single-cell transcriptomes

por Astorkia, Maider, Lachman, Herbert M., Zheng, Deyou
Publicado 2022

Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons

por Wang, Ping, Zhao, Dejian, Lachman, Herbert M., Zheng, Deyou
Publicado 2018

Characterization of Human Pseudogene-Derived Non-Coding RNAs for Functional Potential

por Guo, Xingyi, Lin, Mingyan, Rockowitz, Shira, Lachman, Herbert M., Zheng, Deyou
Publicado 2014

Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis

por Zhao, Dejian, Lin, Mingyan, Pedrosa, Erika, Lachman, Herbert M., Zheng, Deyou
Publicado 2017

Molecular and network disruptions in neurodevelopment uncovered by single cell transcriptomics analysis of CHD8 heterozygous cerebral organoids

por Astorkia, Maider, Liu, Yang, Pedrosa, Erika M., Lachman, Herbert M., Zheng, Deyou
Publicado 2023

Allele-Biased Expression in Differentiating Human Neurons: Implications for Neuropsychiatric Disorders

por Lin, Mingyan, Hrabovsky, Anastasia, Pedrosa, Erika, Wang, Tao, Zheng, Deyou, Lachman, Herbert M.
Publicado 2012

Heat Shock Alters the Expression of Schizophrenia and Autism Candidate Genes in an Induced Pluripotent Stem Cell Model of the Human Telencephalon

por Lin, Mingyan, Zhao, Dejian, Hrabovsky, Anastasia, Pedrosa, Erika, Zheng, Deyou, Lachman, Herbert M.
Publicado 2014

Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stress

por Zhao, Dejian, Mokhtari, Ryan, Pedrosa, Erika, Birnbaum, Rayna, Zheng, Deyou, Lachman, Herbert M.
Publicado 2017

Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells

por Barnes, Jesse, Salas, Franklin, Mokhtari, Ryan, Dolstra, Hedwig, Pedrosa, Erika, Lachman, Herbert M.
Publicado 2018

RNA-Seq of Human Neurons Derived from iPS Cells Reveals Candidate Long Non-Coding RNAs Involved in Neurogenesis and Neuropsychiatric Disorders

por Lin, Mingyan, Pedrosa, Erika, Shah, Abhishek, Hrabovsky, Anastasia, Maqbool, Shahina, Zheng, Deyou, Lachman, Herbert M.
Publicado 2011

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells

por Wang, Ping, Mokhtari, Ryan, Pedrosa, Erika, Kirschenbaum, Michael, Bayrak, Can, Zheng, Deyou, Lachman, Herbert M.
Publicado 2017

Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks

por Nebel, Rebecca A., Zhao, Dejian, Pedrosa, Erika, Kirschen, Jill, Lachman, Herbert M., Zheng, Deyou, Abrahams, Brett S.
Publicado 2016

ZNF804A Transcriptional Networks in Differentiating Neurons Derived from Induced Pluripotent Stem Cells of Human Origin

por Chen, Jian, Lin, Mingyan, Hrabovsky, Anastasia, Pedrosa, Erika, Dean, Jason, Jain, Swati, Zheng, Deyou, Lachman, Herbert M.
Publicado 2015

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment

por Wang, Ping, Lin, Mingyan, Pedrosa, Erika, Hrabovsky, Anastasia, Zhang, Zheng, Guo, Wenjun, Lachman, Herbert M., Zheng, Deyou
Publicado 2015

Transcriptome analysis of neural progenitor cells derived from Lowe syndrome induced pluripotent stem cells: identification of candidate genes for the neurodevelopmental and eye ma...

por Liu, Hequn, Barnes, Jesse, Pedrosa, Erika, Herman, Nathaniel S., Salas, Franklin, Wang, Ping, Zheng, Deyou, Lachman, Herbert M.
Publicado 2020

Proteomics and phosphoproteomics profiling in glutamatergic neurons and microglia in an iPSC model of Jansen de Vries Syndrome

por Aguilan, Jennifer T., Pedrosa, Erika, Dolstra, Hedwig, Baykara, Refia Nur, Barnes, Jesse, Zhang, Jinghang, Sidoli, Simone, Lachman, Herbert M.
Publicado 2023

Transcriptome Comparison of Human Neurons Generated Using Induced Pluripotent Stem Cells Derived from Dental Pulp and Skin Fibroblasts

por Chen, Jian, Lin, Mingyan, Foxe, John J., Pedrosa, Erika, Hrabovsky, Anastasia, Carroll, Reed, Zheng, Deyou, Lachman, Herbert M.
Publicado 2013

MicroRNA Profiling of Neurons Generated Using Induced Pluripotent Stem Cells Derived from Patients with Schizophrenia and Schizoaffective Disorder, and 22q11.2 Del

por Zhao, Dejian, Lin, Mingyan, Chen, Jian, Pedrosa, Erika, Hrabovsky, Anastasia, Fourcade, H. Matthew, Zheng, Deyou, Lachman, Herbert M.
Publicado 2015