IL-1 blockade in inherited fever syndromes - what have we learnt?

por Lachmann, Helen J
Publicado 2011

Familial Mediterranean fever, from pathogenesis to treatment: a contemporary review

por TUFAN, Abdurrahman, LACHMANN, Helen J
Publicado 2020

Developments in the scientific and clinical understanding of autoinflammatory disorders

por Lachmann, Helen J, Hawkins, Philip N
Publicado 2009

Cryopyrin-Associated Periodic Fever Syndrome and the Nervous System

por Keddie, Stephen, Parker, Thomas, Lachmann, Helen J., Ginsberg, Lionel
Publicado 2018

COVID-19 and autoinflammatory diseases: prevalence and outcomes of infection and early experience of vaccination in patients on biologics

por Peet, Claire J, Papadopoulou, Charalampia, Sombrito, Bella Ruth M, Wood, Michael R, Lachmann, Helen J
Publicado 2021

A Retrospective Patient Chart Review and Survey in Patients with Cryopyrin-associated Periodic Syndromes Treated with Anakinra

por Lachmann, Helen J., Arnold, Renée J.G., Gattorno, Marco, Koné-Paut, Isabelle, Ferreira, Alberto, Kümmerle-Deschner, Jasmin
Publicado 2013

Retrospective case series describing the efficacy, safety and cost-effectiveness of a vial-sharing programme for canakinumab treatment for paediatric patients with cryopyrin-associ...

por Elmi, Abdulkadir A., Wynne, Karen, Cheng, Iek L., Eleftheriou, Despina, Lachmann, Helen J., Hawkins, Philip N., Brogan, Paul
Publicado 2019

Pericarditis and Autoinflammation: A Clinical and Genetic Analysis of Patients With Idiopathic Recurrent Pericarditis and Monogenic Autoinflammatory Diseases at a National Referral...

por Peet, Claire J., Rowczenio, Dorota, Omoyinmi, Ebun, Papadopoulou, Charalampia, Mapalo, Bella Ruth R., Wood, Michael R., Capon, Francesca, Lachmann, Helen J.
Publicado 2022

Canakinumab treatment for patients with active recurrent or chronic TNF receptor-associated periodic syndrome (TRAPS): an open-label, phase II study

por Gattorno, Marco, Obici, Laura, Cattalini, Marco, Tormey, Vincent, Abrams, Ken, Davis, Nicole, Speziale, Antonio, Bhansali, Suraj G, Martini, Alberto, Lachmann, Helen J
Publicado 2017

Cardiovascular disease risk assessment in patients with familial Mediterranean fever related renal amyloidosis

por Romano, Micol, Piskin, David, Berard, Roberta A., Jackson, Bradley C., Acikel, Cengizhan, Carrero, Juan J., Lachmann, Helen J., Yilmaz, Mahmut I., Demirkaya, Erkan
Publicado 2020

Whole-Exome Sequencing Revealing Somatic NLRP3 Mosaicism in a Patient With Chronic Infantile Neurologic, Cutaneous, Articular Syndrome

por Omoyinmi, Ebun, Melo Gomes, Sónia, Standing, Ariane, Rowczenio, Dorota M, Eleftheriou, Despina, Klein, Nigel, Aróstegui, Juan I, Lachmann, Helen J, Hawkins, Philip N, Brogan, Paul A
Publicado 2014

A novel mass spectrometry method to identify the serum monoclonal light chain component in systemic light chain amyloidosis

por Sharpley, Faye A., Manwani, Richa, Mahmood, Shameem, Sachchithanantham, Sajitha, Lachmann, Helen J., Gillmore, Julian D., Whelan, Carol J., Fontana, Marianna, Hawkins, Philip N., Wechalekar, Ashutosh D.
Publicado 2019

In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes

por Lachmann, Helen J., Lowe, Philip, Felix, Sandra Daniela, Rordorf, Christiane, Leslie, Kieron, Madhoo, Sheril, Wittkowski, Helmut, Bek, Stephan, Hartmann, Nicole, Bosset, Sophie, Hawkins, Philip N., Jung, Thomas
Publicado 2009

Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-bl...

por Koné-Paut, Isabelle, Lachmann, Helen J, Kuemmerle-Deschner, Jasmin B, Hachulla, Eric, Leslie, Kieron S, Mouy, Richard, Ferreira, Alberto, Lheritier, Karine, Patel, Neha, Preiss, Ralph, Hawkins, Philip N
Publicado 2011

Clinical characteristics in subjects with NLRP3 V198M diagnosed at a single UK center and a review of the literature

por Rowczenio, Dorota M, Trojer, Hadija, Russell, Tonia, Baginska, Anna, Lane, Thirusha, Stewart, Nicola M, Gillmore, Julian D, Hawkins, Philip N, Woo, Patricia, Mikoluc, Bozena, Lachmann, Helen J
Publicado 2013

A randomised placebo controlled trial of anakinra for treating pustular psoriasis: statistical analysis plan for stage two of the APRICOT trial

por Cro, Suzie, Patel, Prakash, Barker, Jonathan, Burden, David A., Griffiths, Christopher E. M., Lachmann, Helen J., Reynolds, Nick J., Warren, Richard B., Capon, Francesca, Smith, Catherine, Cornelius, Victoria
Publicado 2020

Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate

por Bibby, Jack A., Purvis, Harriet A., Hayday, Thomas, Chandra, Anita, Okkenhaug, Klaus, Rosenzweig, Sofia, Aksentijevich, Ivona, Wood, Michael, Lachmann, Helen J., Kemper, Claudia, Cope, Andrew P., Perucha, Esperanza
Publicado 2020

The safety of live-attenuated vaccines in patients using IL-1 or IL-6 blockade: an international survey

por Jeyaratnam, Jerold, ter Haar, Nienke M., Lachmann, Helen J., Kasapcopur, Ozgur, Ombrello, Amanda K., Rigante, Donato, Dedeoglu, Fatma, Baris, Ezgi H., Vastert, Sebastiaan J., Wulffraat, Nico M., Frenkel, Joost
Publicado 2018

Cardiac biomarkers are prognostic in systemic light chain amyloidosis with no cardiac involvement by standard criteria

por Sharpley, Faye A., Fontana, Marianna, Martinez-Naharro, Ana, Manwani, Richa, Mahmood, Shameem, Sachchithanantham, Sajitha, Lachmann, Helen J., Gillmore, Julian D., Whelan, Carol J., Hawkins, Philip N., Wechalekar, Ashutosh D.
Publicado 2020

Early relapse is an adverse prognostic marker in systemic immunoglobulin light chain (AL) Amyloidosis

por Ravichandran, Sriram, Law, Steven, Mahmood, Shameem, Wisniowski, Brenden, Foard, Darren, Fontana, Marianna, Martinez-Naharro, Ana, Whelan, Carol, Gillmore, Julian D., Lachmann, Helen J., Hawkins, Philip N., Wechalekar, Ashutosh D.
Publicado 2022