Pathogenic immune response to therapeutic factor VIII: exacerbated response or failed induction of tolerance?

por Varthaman, Aditi, Lacroix-Desmazes, Sébastien
Publicado 2019

Emerging benefits of Fc fusion technology in the context of recombinant factor VIII replacement therapy

por Meeks, Shannon L., Lacroix‐Desmazes, Sébastien
Publicado 2020

Editorial: Tolerating Factor VIII: Novel Strategies to Prevent and Reverse Neutralizing Anti-FVIII Antibodies

por Lacroix-Desmazes, Sébastien, Pratt, Kathleen P.
Publicado 2021

Autoimmunity as a Predisposition for Infectious Diseases

por Maddur, Mohan S., Vani, Janakiraman, Lacroix-Desmazes, Sébastien, Kaveri, Srinivas, Bayry, Jagadeesh
Publicado 2010

Intravenous immunoglobulin for infectious diseases: back to the pre-antibiotic and passive prophylaxis era?

por Bayry, Jagadeesh, Lacroix-Desmazes, Sébastien, Kazatchkine, Michel D, Kaveri, Srini V
Publicado 2004

“Rational Vaccine Design” for HIV Should Take into Account the Adaptive Potential of Polyreactive Antibodies

por Dimitrov, Jordan D., Kazatchkine, Michel D., Kaveri, Srinivas V., Lacroix-Desmazes, Sebastien
Publicado 2011

Tolerating Factor VIII: Recent Progress

por Lacroix-Desmazes, Sebastien, Voorberg, Jan, Lillicrap, David, Scott, David W., Pratt, Kathleen P.
Publicado 2020

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

por Hadzhieva, Maya, Pashov, Anastas D., Kaveri, Srinivas, Lacroix-Desmazes, Sébastien, Mouquet, Hugo, Dimitrov, Jordan D.
Publicado 2017

Designed Ankyrin Repeat Proteins: A New Approach to Mimic Complex Antigens for Diagnostic Purposes?

por Hausammann, Stefanie, Vogel, Monique, Kremer Hovinga, Johanna A., Lacroix-Desmazes, Sebastien, Stadler, Beda M., Horn, Michael P.
Publicado 2013

Prevention of the anti-factor VIII memory B-cell response by inhibition of Bruton tyrosine kinase in experimental hemophilia A

por Delignat, Sandrine, Russick, Jules, Gangadharan, Bagirath, Rayes, Julie, Ing, Mathieu, Voorberg, Jan, Kaveri, Srinivas V., Lacroix-Desmazes, Sébastien
Publicado 2019

Japanese Encephalitis Virus Infected Human Monocyte-Derived Dendritic Cells Activate a Transcriptional Network Leading to an Antiviral Inflammatory Response

por Chauhan, Shailendra, Rathore, Deepak Kumar, Sachan, Shilpa, Lacroix-Desmazes, Sebastien, Gupta, Nimesh, Awasthi, Amit, Vrati, Sudhanshu, Kalia, Manjula
Publicado 2021

Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme

por Planchais, Cyril, Noe, Remi, Gilbert, Marie, Lecerf, Maxime, Kaveri, Srini V., Lacroix-Desmazes, Sébastien, Roumenina, Lubka T., Dimitrov, Jordan D.
Publicado 2023

Hyperoxidized Species of Heme Have a Potent Capacity to Induce Autoreactivity of Human IgG Antibodies

por Wiatr, Marie, Hadzhieva, Maya, Lecerf, Maxime, Noé, Rémi, Justesen, Sune, Lacroix-Desmazes, Sébastien, Dragon-Durey, Marie-Agnès, Dimitrov, Jordan D.
Publicado 2023

The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice.

por Bou-Jaoudeh, Melissa, Delignat, Sandrine, Daventure, Victoria, Astermark, Jan, Lévesque, Hervé, Dimitrov, Jordan D, Deligne, Claire, Proulle, Valérie, Lacroix-Desmazes, Sébastien
Publicado 2023

Therapeutic normal IgG intravenous immunoglobulin activates Wnt-β-catenin pathway in dendritic cells

por Karnam, Anupama, Rambabu, Naresh, Das, Mrinmoy, Bou-Jaoudeh, Melissa, Delignat, Sandrine, Käsermann, Fabian, Lacroix-Desmazes, Sébastien, Kaveri, Srini V., Bayry, Jagadeesh
Publicado 2020

Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance

por Mimoun, Angelina, Delignat, Sandrine, Peyron, Ivan, Daventure, Victoria, Lecerf, Maxime, Dimitrov, Jordan D., Kaveri, Srinivas V., Bayry, Jagadeesh, Lacroix-Desmazes, Sébastien
Publicado 2020

Removal of Mannose-Ending Glycan at Asn(2118) Abrogates FVIII Presentation by Human Monocyte-Derived Dendritic Cells

por Delignat, Sandrine, Rayes, Julie, Dasgupta, Suryasarathi, Gangadharan, Bagirath, Denis, Cécile V., Christophe, Olivier D., Bayry, Jagadeesh, Kaveri, Srinivas V., Lacroix-Desmazes, Sébastien
Publicado 2020

Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody

por Gupta, Nimesh, de Wispelaere, Mélissanne, Lecerf, Maxime, Kalia, Manjula, Scheel, Tobias, Vrati, Sudhanshu, Berek, Claudia, Kaveri, Srinivas V., Desprès, Philippe, Lacroix-Desmazes, Sébastien, Dimitrov, Jordan D.
Publicado 2015

Complement C3 is a novel modulator of the anti-factor VIII immune response

por Rayes, Julie, Ing, Mathieu, Delignat, Sandrine, Peyron, Ivan, Gilardin, Laurent, Vogel, Carl-Wilhelm, Fritzinger, David C., Frémeaux-Bacchi, Véronique, Kaveri, Srinivas V., Roumenina, Lubka T., Lacroix-Desmazes, Sébastien
Publicado 2018

Affinity-Purified Respiratory Syncytial Virus Antibodies from Intravenous Immunoglobulin Exert Potent Antibody-Dependent Cellular Cytotoxicity

por Gupta, Nimesh, LeGoff, Jerome, Chamat, Soulaima, Mercier-Delarue, Severine, Touzelet, Olivier, Power, Ultan F., Kazatchkine, Michel D., Simon, Francois, Lacroix-Desmazes, Sebastien, Bayry, Jagadeesh, Kaveri, Srinivas V.
Publicado 2013