Beneficial metabolic effects of recurrent periods of beta‐cell rest and stimulation using stable neuropeptide Y1 and glucagon‐like peptide‐1 receptor agonists

por Tanday, Neil, Lafferty, Ryan A., Flatt, Peter R., Irwin, Nigel
Publicado 2022

Effects of 2 Novel PYY(1-36) Analogues, (P(3)L(31)P(34))PYY(1-36) and PYY(1-36)(Lys(12)PAL), on Pancreatic Beta-Cell Function, Growth, and Survival

por Lafferty, Ryan A, Gault, Victor A, Flatt, Peter R, Irwin, Nigel
Publicado 2019

Benefits of Sustained Upregulated Unimolecular GLP-1 and CCK Receptor Signalling in Obesity-Diabetes

por Tanday, Neil, English, Andrew, Lafferty, Ryan A., Flatt, Peter R., Irwin, Nigel
Publicado 2021

Beneficial impact of Ac3IV, an AVP analogue acting specifically at V1a and V1b receptors, on diabetes islet morphology and transdifferentiation of alpha- and beta-cells

por Mohan, Shruti, Lafferty, Ryan, Tanday, Neil, Flatt, Peter R., Moffett, R. Charlotte, Irwin, Nigel
Publicado 2021

Proglucagon-Derived Peptides as Therapeutics

por Lafferty, Ryan A., O’Harte, Finbarr P. M., Irwin, Nigel, Gault, Victor A., Flatt, Peter R.
Publicado 2021

Positive Effects of NPY1 Receptor Activation on Islet Structure Are Driven by Pancreatic Alpha- and Beta-Cell Transdifferentiation in Diabetic Mice

por Lafferty, Ryan A., Tanday, Neil, Moffett, R. Charlotte, Reimann, Frank, Gribble, Fiona M., Flatt, Peter R., Irwin, Nigel
Publicado 2021

Sustained glucagon receptor antagonism in insulin-deficient high-fat-fed mice

por Lafferty, Ryan A, McShane, Laura M, Franklin, Zara J, Flatt, Peter R, O’Harte, Finbarr P M, Irwin, Nigel
Publicado 2022

Physicochemical, Nutritional and In Vitro Antidiabetic Characterisation of Blue Whiting (Micromesistius poutassou) Protein Hydrolysates

por Harnedy-Rothwell, Pádraigín A, Khatib, Neda, Sharkey, Shaun, Lafferty, Ryan A, Gite, Snehal, Whooley, Jason, O’Harte, Finbarr PM, FitzGerald, Richard J
Publicado 2021