Population Pharmacokinetics of a Monthly Buprenorphine Depot Injection for the Treatment of Opioid Use Disorder: A Combined Analysis of Phase II and Phase III Trials

por Jones, Aksana K., Ngaimisi, Eliford, Gopalakrishnan, Mathangi, Young, Malcolm A., Laffont, Celine M.
Publicado 2020

Evaluation of Drug‐Drug Interaction Liability for Buprenorphine Extended‐Release Monthly Injection Administered by Subcutaneous Route

por Kharidia, Jahnavi, Howgate, Eleanor M., Laffont, Celine M., Liu, Yongzhen, Young, Malcolm A.
Publicado 2021

Examining the benefit of a higher maintenance dose of extended-release buprenorphine in opioid-injecting participants treated for opioid use disorder

por Greenwald, Mark K., Wiest, Katharina L., Haight, Barbara R., Laffont, Celine M., Zhao, Yue
Publicado 2023

Buprenorphine exposure levels to optimize treatment outcomes in opioid use disorder

por Laffont, Celine M., Ngaimisi, Eliford, Gopalakrishnan, Mathangi, Ivaturi, Vijay, Young, Malcolm, Greenwald, Mark K., Heidbreder, Christian
Publicado 2022

Evaluation of the Effects of a Monthly Buprenorphine Depot Subcutaneous Injection on QT Interval During Treatment for Opioid Use Disorder

por Schmith, Virginia D., Curd, Laura, Lohmer, Lauren R. L., Laffont, Celine M., Andorn, Anne, Young, Malcolm A.
Publicado 2019

A Delta-Opioid Receptor Gene Polymorphism Moderates the Therapeutic Response to Extended-Release Buprenorphine in Opioid Use Disorder

por Kranzler, Henry R, Lynch, Kevin G, Crist, Richard C, Hartwell, Emily, Le Moigne, Anne, Laffont, Celine M, Andorn, Anne C
Publicado 2020

Bisphenol A in Thermal Paper Receipts: Taylor et al. Respond

por Taylor, Julia A., vom Saal, Frederick S., Welshons, Wade V., Drury, Bertram, Rottinghaus, George, Hunt, Patricia A., Toutain, Pierre-Louis, Laffont, Céline M.
Publicado 2012

Modeling buprenorphine reduction of fentanyl-induced respiratory depression

por Olofsen, Erik, Algera, Marijke Hyke, Moss, Laurence, Dobbins, Robert L., Groeneveld, Geert J., van Velzen, Monique, Niesters, Marieke, Dahan, Albert, Laffont, Celine M.
Publicado 2022

A whole-body physiologically based pharmacokinetic (WB-PBPK) model of ciprofloxacin: a step towards predicting bacterial killing at sites of infection

por Sadiq, Muhammad W., Nielsen, Elisabet I., Khachman, Dalia, Conil, Jean-Marie, Georges, Bernard, Houin, Georges, Laffont, Celine M., Karlsson, Mats O., Friberg, Lena E.
Publicado 2016

Pharmacokinetics of Sublingual Buprenorphine Tablets Following Single and Multiple Doses in Chinese Participants With and Without Opioid Use Disorder

por Dong, Ruihua, Wang, Hongyun, Li, Dandan, Lang, Liwei, Gray, Frank, Liu, Yongzhen, Laffont, Celine M., Young, Malcolm, Jiang, Ji, Liu, Zeyuan, Learned, Susan M.
Publicado 2019

Tolerance to Opioid‐Induced Respiratory Depression in Chronic High‐Dose Opioid Users: A Model‐Based Comparison With Opioid‐Naïve Individuals

por Algera, Marijke Hyke, Olofsen, Erik, Moss, Laurence, Dobbins, Robert L., Niesters, Marieke, van Velzen, Monique, Groeneveld, Geert Jan, Heuberger, Jules, Laffont, Celine M., Dahan, Albert
Publicado 2020

Similarity of Bisphenol A Pharmacokinetics in Rhesus Monkeys and Mice: Relevance for Human Exposure

por Taylor, Julia A., vom Saal, Frederick S., Welshons, Wade V., Drury, Bertram, Rottinghaus, George, Hunt, Patricia A., Toutain, Pierre-Louis, Laffont, Céline M., VandeVoort, Catherine A.
Publicado 2011

Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-toler...

por Moss, Laurence M., Algera, Marijke Hyke, Dobbins, Robert, Gray, Frank, Strafford, Stephanie, Heath, Amy, van Velzen, Monique, Heuberger, Jules A. A. C., Niesters, Marieke, Olofsen, Erik, Laffont, Celine M., Dahan, Albert, Groeneveld, Geert Jan
Publicado 2022