New Insights into the Mechanisms of Innate Immune Receptor Signalling in Fibrosis

por Lafyatis, Robert, Farina, Alessandra
Publicado 2012

Toll-like receptors and innate immune responses in systemic lupus erythematosus

por Lafyatis, Robert, Marshak-Rothstein, Ann
Publicado 2007

The cytokine language of monocytes and macrophages in systemic sclerosis

por Christmann, Romy B, Lafyatis, Robert
Publicado 2010

Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions

por Krieg, Thomas, Abraham, David, Lafyatis, Robert
Publicado 2007

Increased dermal collagen bundle alignment in systemic sclerosis is associated with a cell migration signature and role of Arhgdib in directed fibroblast migration on aligned ECMs

por Cao, Lizhi, Lafyatis, Robert, Burkly, Linda C.
Publicado 2017

Elevated expression of cav-1 in a subset of SSc fibroblasts contributes to constitutive Alk1/Smad1 activation

por Haines, Paul, Hant, Faye N, Lafyatis, Robert, Trojanowska, Maria, Bujor, Andreea M
Publicado 2012

The mycosis fungoides cutaneous microenvironment shapes dysfunctional cell trafficking, antitumor immunity, matrix interactions, and angiogenesis

por Gaydosik, Alyxzandria M., Stonesifer, Connor J., Tabib, Tracy, Lafyatis, Robert, Geskin, Larisa J., Fuschiotti, Patrizia
Publicado 2023

Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies

por Pendergrass, Sarah A., Lemaire, Raphael, Francis, Ian, Mahoney, J. Matthew, Lafyatis, Robert, Whitfield, Michael L.
Publicado 2012

Single-Cell Transcriptome Analysis Identifies Subclusters with Inflammatory Fibroblast Responses in Localized Scleroderma

por Werner, Giffin, Sanyal, Anwesha, Mirizio, Emily, Hutchins, Theresa, Tabib, Tracy, Lafyatis, Robert, Jacobe, Heidi, Torok, Kathryn S.
Publicado 2023

Single-cell transcriptome conservation in a comparative analysis of fresh and cryopreserved human skin tissue: pilot in localized scleroderma

por Mirizio, Emily, Tabib, Tracy, Wang, Xiao, Chen, Wei, Liu, Christopher, Lafyatis, Robert, Jacobe, Heidi, Torok, Kathryn S.
Publicado 2020

Correction to: Single-cell transcriptome conservation in a comparative analysis of fresh and cryopreserved human skin tissue: pilot in localized scleroderma

por Mirizio, Emily, Tabib, Tracy, Wang, Xinjun, Chen, Wei, Liu, Christopher, Lafyatis, Robert, Jacobe, Heidi, Torok, Kathryn S.
Publicado 2021

Disparate Interferon Signaling and Shared Aberrant Basaloid Cells in Single-Cell Profiling of Idiopathic Pulmonary Fibrosis and Systemic Sclerosis-Associated Interstitial Lung Dise...

por Valenzi, Eleanor, Tabib, Tracy, Papazoglou, Anna, Sembrat, John, Trejo Bittar, Humberto E., Rojas, Mauricio, Lafyatis, Robert
Publicado 2021

Limited Systemic Sclerosis Patients with Pulmonary Arterial Hypertension Show Biomarkers of Inflammation and Vascular Injury

por Pendergrass, Sarah A., Hayes, Everett, Farina, Giuseppina, Lemaire, Raphael, Farber, Harrison W., Whitfield, Michael L., Lafyatis, Robert
Publicado 2010

p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis

por Ghosh, Asish K, Bhattacharyya, Swati, Lafyatis, Robert, Farina, Giuseppina, Yu, Jianxiu, Thimmapaya, Bayar, Wei, Jun, Varga, John
Publicado 2013

Single Cell RNA Sequencing Identifies HSPG2 and APLNR as Markers of Endothelial Cell Injury in Systemic Sclerosis Skin

por Apostolidis, Sokratis A., Stifano, Giuseppina, Tabib, Tracy, Rice, Lisa M., Morse, Christina M., Kahaleh, Bashar, Lafyatis, Robert
Publicado 2018

HLA-B35 and dsRNA Induce Endothelin-1 via Activation of ATF4 in Human Microvascular Endothelial Cells

por Lenna, Stefania, Chrobak, Izabela, Farina, G. Alessandra, Rodriguez-Pascual, Fernando, Lamas, Santiago, Lafyatis, Robert, Scorza, Raffaella, Trojanowska, Maria
Publicado 2013

Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension

por Saygin, Didem, Tabib, Tracy, Bittar, Humberto E.T., Valenzi, Eleanor, Sembrat, John, Chan, Stephen Y., Rojas, Mauricio, Lafyatis, Robert
Publicado 2020

The HLA-B*35 allele modulates ER stress, inflammation and proliferation in PBMCs from Limited Cutaneous Systemic Sclerosis patients

por Lenna, Stefania, Assassi, Shervin, Farina, G. Alessandra, Mantero, Julio C., Scorza, Raffaella, Lafyatis, Robert, Farber, Harrison W., Trojanowska, Maria
Publicado 2015

Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1

por BUJOR, ANDREEA M., HAINES, PAUL, PADILLA, CRISTINA, CHRISTMANN, ROMY B., JUNIE, MONICA, SAMPAIO-BARROS, PERCIVAL D., LAFYATIS, ROBERT, TROJANOWSKA, MARIA
Publicado 2012

Stretching Reduces Skin Thickness and Improves Subcutaneous Tissue Mobility in a Murine Model of Systemic Sclerosis

por Xiong, Ying, Berrueta, Lisbeth, Urso, Katia, Olenich, Sara, Muskaj, Igla, Badger, Gary J., Aliprantis, Antonios, Lafyatis, Robert, Langevin, Helene M.
Publicado 2017