Prediction of cancer driver genes through network-based moment propagation of mutation scores

por Gumpinger, Anja C, Lage, Kasper, Horn, Heiko, Borgwardt, Karsten
Publicado 2020

Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells

por Dubonyte, Ugne, Asenjo-Martinez, Andrea, Werge, Thomas, Lage, Kasper, Kirkeby, Agnete
Publicado 2022

MetaRanker 2.0: a web server for prioritization of genetic variation data

por Pers, Tune H., Dworzyński, Piotr, Thomas, Cecilia Engel, Lage, Kasper, Brunak, Søren
Publicado 2013

Expression Profiling of Human Genetic and Protein Interaction Networks in Type 1 Diabetes

por Bergholdt, Regine, Brorsson, Caroline, Lage, Kasper, Nielsen, Jens Høiriis, Brunak, Søren, Pociot, Flemming
Publicado 2009

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues

por Lundby, Alicia, Secher, Anna, Lage, Kasper, Nordsborg, Nikolai B., Dmytriyev, Anatoliy, Lundby, Carsten, Olsen, Jesper V.
Publicado 2012

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

por Rossin, Elizabeth J., Lage, Kasper, Raychaudhuri, Soumya, Xavier, Ramnik J., Tatar, Diana, Benita, Yair, Cotsapas, Chris, Daly, Mark J.
Publicado 2011

Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease

por Won, Hong-Hee, Natarajan, Pradeep, Dobbyn, Amanda, Jordan, Daniel M., Roussos, Panos, Lage, Kasper, Raychaudhuri, Soumya, Stahl, Eli, Do, Ron
Publicado 2015

Systematic auditing is essential to debiasing machine learning in biology

por Eid, Fatma-Elzahraa, Elmarakeby, Haitham A., Chan, Yujia Alina, Fornelos, Nadine, ElHefnawi, Mahmoud, Van Allen, Eliezer M., Heath, Lenwood S., Lage, Kasper
Publicado 2021

Integrative analysis for finding genes and networks involved in diabetes and other complex diseases

por Bergholdt, Regine, Størling, Zenia M, Lage, Kasper, Karlberg, E Olof, Ólason, Páll Í, Aalund, Mogens, Nerup, Jørn, Brunak, Søren, Workman, Christopher T, Pociot, Flemming
Publicado 2007

Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data

por Fernández-Tajes, Juan, Gaulton, Kyle J., van de Bunt, Martijn, Torres, Jason, Thurner, Matthias, Mahajan, Anubha, Gloyn, Anna L., Lage, Kasper, McCarthy, Mark I.
Publicado 2019

Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns

por Lundby, Alicia, Lage, Kasper, Weinert, Brian T., Bekker-Jensen, Dorte B., Secher, Anna, Skovgaard, Tine, Kelstrup, Christian D., Dmytriyev, Anatoliy, Choudhary, Chunaram, Lundby, Carsten, Olsen, Jesper V.
Publicado 2012

Genoppi is an open-source software for robust and standardized integration of proteomic and genetic data

por Pintacuda, Greta, Lassen, Frederik H., Hsu, Yu-Han H., Kim, April, Martín, Jacqueline M., Malolepsza, Edyta, Lim, Justin K., Fornelos, Nadine, Eggan, Kevin C., Lage, Kasper
Publicado 2021

CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis

por Sosulski, Amanda, Horn, Heiko, Zhang, Lihua, Coletti, Caroline, Vathipadiekal, Vinod, Castro, Cesar M., Birrer, Michael J., Nagano, Osamu, Saya, Hideyuki, Lage, Kasper, Donahoe, Patricia K., Pépin, David
Publicado 2016

Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction

por Sun, Jiangming, Wang, Yunpeng, Folkersen, Lasse, Borné, Yan, Amlien, Inge, Buil, Alfonso, Orho-Melander, Marju, Børglum, Anders D., Hougaard, David M., Melander, Olle, Engström, Gunnar, Werge, Thomas, Lage, Kasper
Publicado 2021

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology

por Tanigawa, Yosuke, Li, Jiehan, Justesen, Johanne M., Horn, Heiko, Aguirre, Matthew, DeBoever, Christopher, Chang, Chris, Narasimhan, Balasubramanian, Lage, Kasper, Hastie, Trevor, Park, Chong Y., Bejerano, Gill, Ingelsson, Erik, Rivas, Manuel A.
Publicado 2019

NetSig: network-based discovery from cancer genomes

por Horn, Heiko, Lawrence, Michael S., Chouinard, Candace R., Shrestha, Yashaswi, Hu, Jessica Xin, Worstell, Elizabeth, Shea, Emily, Ilic, Nina, Kim, Eejung, Kamburov, Atanas, Kashani, Alireza, Hahn, William C., Campbell, Joshua D., Boehm, Jesse S., Getz, Gad, Lage, Kasper
Publicado 2017

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selec...

por Riley, Brigit E., Kaiser, Stephen E., Shaler, Thomas A., Ng, Aylwin C.Y., Hara, Taichi, Hipp, Mark S., Lage, Kasper, Xavier, Ramnik J., Ryu, Kwon-Yul, Taguchi, Keiko, Yamamoto, Masayuki, Tanaka, Keiji, Mizushima, Noboru, Komatsu, Masaaki, Kopito, Ron R.
Publicado 2010

Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants

por Iqbal, Sumaiya, Pérez-Palma, Eduardo, Jespersen, Jakob B., May, Patrick, Hoksza, David, Heyne, Henrike O., Ahmed, Shehab S., Rifat, Zaara T., Rahman, M. Sohel, Lage, Kasper, Palotie, Aarno, Cottrell, Jeffrey R., Wagner, Florence F., Daly, Mark J., Campbell, Arthur J., Lal, Dennis
Publicado 2020

Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders

por Pintacuda, Greta, Hsu, Yu-Han H., Tsafou, Kalliopi, Li, Ka Wan, Martín, Jacqueline M., Riseman, Jackson, Biagini, Julia C., Ching, Joshua K.T., Mena, Daya, Gonzalez-Lozano, Miguel A., Egri, Shawn B., Jaffe, Jake, Smit, August B., Fornelos, Nadine, Eggan, Kevin C., Lage, Kasper
Publicado 2023

Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility

por Saatcioglu, Hatice Duygu, Kano, Motohiro, Horn, Heiko, Zhang, Lihua, Samore, Wesley, Nagykery, Nicholas, Meinsohn, Marie-Charlotte, Hyun, Minsuk, Suliman, Rana, Poulo, Joy, Hsu, Jennifer, Sacha, Caitlin, Wang, Dan, Gao, Guangping, Lage, Kasper, Oliva, Esther, Morris Sabatini, Mary E, Donahoe, Patricia K, Pépin, David
Publicado 2019