An Amphipathic Alpha-Helix in the Prodomain of Cocaine and Amphetamine Regulated Transcript Peptide Precursor Serves as Its Sorting Signal to the Regulated Secretory Pathway

por Blanco, Elías H., Lagos, Carlos F., Andrés, María Estela, Gysling, Katia
Publicado 2013

Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor

por Slater, Paula G., Gutierrez-Maldonado, Sebastian E., Gysling, Katia, Lagos, Carlos F.
Publicado 2018

Novel FXa Inhibitor Identification through Integration of Ligand- and Structure-Based Approaches

por Lagos, Carlos F., Segovia, Gerardine F., Nuñez-Navarro, Nicolás, Faúndez, Mario A., Zacconi, Flavia C.
Publicado 2017

Divergent Metabolic Phenotype between Two Sisters with Congenital Generalized Lipodystrophy Due to Double AGPAT2 Homozygous Mutations. A Clinical, Genetic and In Silico Study

por Cortés, Víctor A., Smalley, Susan V., Goldenberg, Denisse, Lagos, Carlos F., Hodgson, María I., Santos, José L.
Publicado 2014

Late-onset X-linked adrenal hypoplasia (DAX-1, NR0B1): two new adult-onset cases from a single center

por Kyriakakis, Nikolaos, Shonibare, Tolulope, Kyaw-Tun, Julie, Lynch, Julie, Lagos, Carlos F., Achermann, John C., Murray, Robert D.
Publicado 2017

Innovative Three-Step Microwave-Promoted Synthesis of N-Propargyltetrahydroquinoline and 1,2,3-Triazole Derivatives as a Potential Factor Xa (FXa) Inhibitors: Drug Design, Synthesi...

por Santana-Romo, Fabián, Lagos, Carlos F., Duarte, Yorley, Castillo, Francisco, Moglie, Yanina, Maestro, Miguel A., Charbe, Nitin, Zacconi, Flavia C.
Publicado 2020

Inhibition of connexin hemichannels alleviates neuroinflammation and hyperexcitability in temporal lobe epilepsy

por Guo, Anni, Zhang, Huiqi, Li, Huanhuan, Chiu, Arthur, García-Rodríguez, Claudia, Lagos, Carlos F., Sáez, Juan C., Lau, Chunyue Geoffrey
Publicado 2022

Fluorescence enzymatic assay for bacterial polyphosphate kinase 1 (PPK1) as a platform for screening antivirulence molecules

por Campos, Francisca, Álvarez, Javiera A, Ortiz-Severín, Javiera, Varas, Macarena A, Lagos, Carlos F, Cabrera, Ricardo, Álvarez, Sergio A, Chávez, Francisco P
Publicado 2019

LC–MS/MS Method for the Simultaneous Determination of Free Urinary Steroids

por Allende, Fidel, Solari, Sandra, Campino, Carmen, Carvajal, Cristian A., Lagos, Carlos F., Vecchiola, Andrea, Valdivia, Carolina, Baudrand, René, Owen, Gareth I., Fardella, Carlos E.
Publicado 2014

Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1

por de la Fuente-Ortega, Erwin, Gravotta, Diego, Bay, Andres Perez, Benedicto, Ignacio, Carvajal-Gonzalez, Jose Maria, Lehmann, Guillermo L., Lagos, Carlos F., Rodríguez-Boulan, Enrique
Publicado 2015

2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β(3)-Adrenergic Activity

por Apablaza, Gastón, Montoya, Luisa, Morales-Verdejo, Cesar, Mellado, Marco, Cuellar, Mauricio, Lagos, Carlos F., Soto-Delgado, Jorge, Chung, Hery, Pessoa-Mahana, Carlos David, Mella, Jaime
Publicado 2017

Novel N-Arylsulfonylindoles Targeted as Ligands of the 5-HT(6) Receptor. Insights on the Influence of C-5 Substitution on Ligand Affinity

por Arrieta-Rodríguez, Loreto, Espinoza-Rosales, Daniela, Vera, Gonzalo, Cho, Young Hwa, Cabezas, David, Vásquez-Velásquez, David, Mella-Raipán, Jaime, Lagos, Carlos F., Recabarren-Gajardo, Gonzalo
Publicado 2021

Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands

por Mella-Raipán, Jaime A., Lagos, Carlos F., Recabarren-Gajardo, Gonzalo, Espinosa-Bustos, Christian, Romero-Parra, Javier, Pessoa-Mahana, Hernán, Iturriaga-Vásquez, Patricio, Pessoa-Mahana, Carlos David
Publicado 2013

Extended N-Arylsulfonylindoles as 5-HT(6) Receptor Antagonists: Design, Synthesis & Biological Evaluation

por Vera, Gonzalo, Lagos, Carlos F., Almendras, Sebastián, Hebel, Dan, Flores, Francisco, Valle-Corvalán, Gissella, Pessoa-Mahana, C. David, Mella-Raipán, Jaime, Montecinos, Rodrigo, Recabarren-Gajardo, Gonzalo
Publicado 2016

Eplerenone Implantation Improved Adipose Dysfunction Averting RAAS Activation and Cell Division

por Vecchiola, Andrea, Fuentes, Cristóbal A., Solar, Isidora, Lagos, Carlos F., Opazo, Maria Cecilia, Muñoz-Durango, Natalia, Riedel, Claudia A., Owen, Gareth I., Kalergis, Alexis M., Fardella, Carlos E.
Publicado 2020

Novel splice-affecting variants in CYP27A1 gene in two Chilean patients with Cerebrotendinous Xanthomatosis

por Smalley, Susan V., Preiss, Yudith, Suazo, José, Vega, Javier Andrés, Angellotti, Isidora, Lagos, Carlos F., Rivera, Enzo, Kleinsteuber, Karin, Campion, Javier, Martínez, J. Alfredo, Maiz, Alberto, Santos, José Luis
Publicado 2015

APOA5 Q97X Mutation Identified through homozygosity mapping causes severe hypertriglyceridemia in a Chilean consanguineous family

por Dussaillant, Catalina, Serrano, Valentina, Maiz, Alberto, Eyheramendy, Susana, Cataldo, Luis Rodrigo, Chavez, Matías, Smalley, Susan V, Fuentes, Marcela, Rigotti, Attilio, Rubio, Lorena, Lagos, Carlos F, Martinez, José Alfredo, Santos, José Luis
Publicado 2012

Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro

por Vecchiola, Andrea, Lagos, Carlos F, Fuentes, Cristóbal A, Allende, Fidel, Campino, Carmen, Valdivia, Carolina, Tapia-Castillo, Alejandra, Ogishima, Tadashi, Mukai, Kuniaki, Owen, Gareth, Solari, Sandra, Carvajal, Cristian A, Fardella, Carlos E
Publicado 2013

Next-Generation Sequencing Reveals Novel Genetic Variants (SRY, DMRT1, NR5A1, DHH, DHX37) in Adults With 46,XY DSD

por Buonocore, Federica, Clifford-Mobley, Oliver, King, Tom F J, Striglioni, Niccolò, Man, Elim, Suntharalingham, Jenifer P, del Valle, Ignacio, Lin, Lin, Lagos, Carlos F, Rumsby, Gill, Conway, Gerard S, Achermann, John C
Publicado 2019

Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function

por Jara, Oscar, Acuña, Rodrigo, García, Isaac E., Maripillán, Jaime, Figueroa, Vania, Sáez, Juan C., Araya-Secchi, Raúl, Lagos, Carlos F., Pérez-Acle, Tomas, Berthoud, Viviana M., Beyer, Eric C., Martínez, Agustín D.
Publicado 2012