PE and PET oligomers’ interplay with membrane bilayers

por Järvenpää, Joni, Perkkiö, Milla, Laitinen, Riikka, Lahtela-Kakkonen, Maija
Publicado 2022

SIRT2i_Predictor: A Machine Learning-Based Tool to Facilitate the Discovery of Novel SIRT2 Inhibitors

por Djokovic, Nemanja, Rahnasto-Rilla, Minna, Lougiakis, Nikolaos, Lahtela-Kakkonen, Maija, Nikolic, Katarina
Publicado 2023

BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses

por Kokkola, Tarja, Suuronen, Tiina, Pesonen, Maija, Filippakopoulos, Panagis, Salminen, Antero, Jarho, Elina M, Lahtela-Kakkonen, Maija
Publicado 2015

Synthesis and Evaluation of Substituted Chroman-4-one and Chromone Derivatives as Sirtuin 2-Selective Inhibitors

por Fridén-Saxin, Maria, Seifert, Tina, Landergren, Marie Rydén, Suuronen, Tiina, Lahtela-Kakkonen, Maija, Jarho, Elina M., Luthman, Kristina
Publicado 2012

Sirtuin functions and modulation: from chemistry to the clinic

por Carafa, Vincenzo, Rotili, Dante, Forgione, Mariantonietta, Cuomo, Francesca, Serretiello, Enrica, Hailu, Gebremedhin Solomon, Jarho, Elina, Lahtela-Kakkonen, Maija, Mai, Antonello, Altucci, Lucia
Publicado 2016

The Identification of a SIRT6 Activator from Brown Algae Fucus distichus

por Rahnasto-Rilla, Minna K., McLoughlin, Padraig, Kulikowicz, Tomasz, Doyle, Maire, Bohr, Vilhelm A., Lahtela-Kakkonen, Maija, Ferrucci, Luigi, Hayes, Maria, Moaddel, Ruin
Publicado 2017

Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, “selectivity pocket” and NAD(+)-binding site

por Mellini, Paolo, Itoh, Yukihiro, Tsumoto, Hiroki, Li, Ying, Suzuki, Miki, Tokuda, Natsuko, Kakizawa, Taeko, Miura, Yuri, Takeuchi, Jun, Lahtela-Kakkonen, Maija, Suzuki, Takayoshi
Publicado 2017

Natural polyphenols as sirtuin 6 modulators

por Rahnasto-Rilla, Minna, Tyni, Jonna, Huovinen, Marjo, Jarho, Elina, Kulikowicz, Tomasz, Ravichandran, Sarangan, A. Bohr, Vilhelm, Ferrucci, Luigi, Lahtela-Kakkonen, Maija, Moaddel, Ruin
Publicado 2018

2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors

por Pätsi, Henri T., Kilpeläinen, Tommi P., Auno, Samuli, Dillemuth, Pyry M. J., Arja, Khaled, Lahtela-Kakkonen, Maija K., Myöhänen, Timo T., Wallén, Erik A. A.
Publicado 2021

A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites

por Milenkovic, Dragan, Berghe, Wim Vanden, Morand, Christine, Claude, Sylvain, van de Sandt, Annette, Gorressen, Simone, Monfoulet, Laurent-Emmanuel, Chirumamilla, Chandra S., Declerck, Ken, Szic, Katarzyna Szarc vel, Lahtela-Kakkonen, Maija, Gerhauser, Clarissa, Merx, Marc W., Kelm, Malte
Publicado 2018