No relevant cardiac, pharmacokinetic or safety interactions between roflumilast and inhaled formoterol in healthy subjects: an open-label, randomised, actively controlled study

por de Mey, Christian, Nassr, Nassr, Lahu, Gezim
Publicado 2011

Pharmacokinetic and Pharmacodynamic Modelling to Characterize the Tolerability of Alternative Up-Titration Regimens of Roflumilast in Patients with Chronic Obstructive Pulmonary Di...

por Facius, Axel, Marostica, Eleonora, Gardiner, Philip, Watz, Henrik, Lahu, Gezim
Publicado 2018

Constant-load exercise decreases the serum concentration of myeloperoxidase in healthy smokers and smokers with COPD

por Holz, Olaf, Roepcke, Stefan, Watz, Henrik, Tegtbur, Uwe, Lahu, Gezim, Hohlfeld, Jens M
Publicado 2015

Population pharmacokinetics, enzyme occupancy, and 24S‐hydroxycholesterol modeling of soticlestat, a novel cholesterol 24‐hydroxylase inhibitor, in healthy adults

por Yin, Wei, Facius, Axel, Wagner, Thomas, Tsai, Max, Asgharnejad, Mahnaz, Lahu, Gëzim, Vakilynejad, Majid
Publicado 2023

Population Pharmacokinetic Meta-Analysis to Bridge Ferumoxytol Plasma Pharmacokinetics Across Populations

por Plock, Nele, Facius, Axel, Lahu, Gezim, Wood, Nolan, Frigo, Timothy, Deveney, Aaron, Aceves, Pau
Publicado 2014

Pharmacokinetics and pharmacodynamics of the cytolytic anti‐CD38 human monoclonal antibody TAK‐079 in monkey – model assisted preparation for the first in human trial

por Roepcke, Stefan, Plock, Nele, Yuan, Josh, Fedyk, Eric R., Lahu, Gezim, Zhao, Lin, Smithson, Glennda
Publicado 2018

What Can Be Learned From Crowdsourced Population Asparagus Urinary Odor Kinetics?

por Facius, Axel, Atkinson, Linda A., Hanna, Kelly, Coombes, Mai Chi, Lahu, Gezim, Wagner, John A.
Publicado 2019

Prediction of Nephropathy in Type 2 Diabetes: An Analysis of the ACCORD Trial Applying Machine Learning Techniques

por Rodriguez‐Romero, Violeta, Bergstrom, Richard F., Decker, Brian S., Lahu, Gezim, Vakilynejad, Majid, Bies, Robert R.
Publicado 2019

Model‐Based Approach to Predict Adherence to Protocol During Antiobesity Trials

por Sharma, Vishnu D., Combes, François P., Vakilynejad, Majid, Lahu, Gezim, Lesko, Lawrence J., Trame, Mirjam N.
Publicado 2017

A Population Pharmacokinetic Model of Vonoprazan: Evaluating the Effects of Race, Disease Status, and Other Covariates on Exposure

por Scarpignato, Carmelo, Leifke, Eckhard, Smith, Neila, Mulford, Darcy J., Lahu, Gezim, Facius, Axel, Howden, Colin W.
Publicado 2022

A case study of a patient‐centered reverse translational systems‐based approach to understand adverse event profiles in drug development

por Kim, Sarah, Lahu, Gezim, Vakilynejad, Majid, Soldatos, Theodoros G., Jackson, David B., Lesko, Lawrence J., Trame, Mirjam N.
Publicado 2022

Application of a patient‐centered reverse translational systems‐based approach to understand mechanisms of an adverse drug reaction of immune checkpoint inhibitors

por Kim, Sarah, Lahu, Gezim, Vakilynejad, Majid, Soldatos, Theodoros G., Jackson, David B., Lesko, Lawrence J., Trame, Mirjam N.
Publicado 2022

Repeatability of and Relationship between Potential COPD Biomarkers in Bronchoalveolar Lavage, Bronchial Biopsies, Serum, and Induced Sputum

por Röpcke, Stefan, Holz, Olaf, Lauer, Gereon, Müller, Meike, Rittinghausen, Susanne, Ernst, Peter, Lahu, Gezim, Elmlinger, Martin, Krug, Norbert, Hohlfeld, Jens M.
Publicado 2012

Safety, tolerability, pharmacokinetics and pharmacodynamics of the anti‐CD38 cytolytic antibody TAK‐079 in healthy subjects

por Fedyk, Eric R., Zhao, Lin, Koch, Annelize, Smithson, Glennda, Estevam, Jose, Chen, Grace, Lahu, Gezim, Roepcke, Stefan, Lin, Jianchang, Mclean, Lachy
Publicado 2020