Involvement of NADPH oxidases in the Na/K‑ATPase/Src/ROS oxidant amplification loop in renal fibrosis

por Zhang, Huimin, Lai, Fangfang, Cheng, Xi, Wang, Yu
Publicado 2023

LXY6090 – a novel manassantin A derivative – limits breast cancer growth through hypoxia-inducible factor-1 inhibition

por Lai, Fangfang, Liu, Qian, Liu, Xiaoyu, Ji, Ming, Xie, Ping, Chen, Xiaoguang
Publicado 2016

Quantitative Evaluation of in Vivo Target Efficacy of Anti-tumor Agents via an Immunofluorescence and EdU Labeling Strategy

por He, Yujun, Wen, Jin, Cui, Qinghua, Lai, Fangfang, Yin, Dali, Cui, Huaqing
Publicado 2018

Design, Synthesis and Biological Evaluation of Phenyl Urea Derivatives as IDO1 Inhibitors

por Zhou, Chuan, Lai, Fangfang, Sheng, Li, Chen, Xiaoguang, Li, Yan, Feng, Zhiqiang
Publicado 2020

Secreted HSP90α-LRP1 Signaling Promotes Tumor Metastasis and Chemoresistance in Pancreatic Cancer

por Xue, Nina, Du, Tingting, Lai, Fangfang, Jin, Jing, Ji, Ming, Chen, Xiaoguang
Publicado 2022

CAT(3), a prodrug of 13a(S)-3-hydroxyl-6,7-dimethoxyphenanthro[9,10-b]-indolizidine, circumvents temozolomide-resistant glioblastoma via the Hedgehog signaling pathway, independent...

por Ji, Ming, Wang, Liyuan, Chen, Ju, Xue, Nina, Wang, Chunyang, Lai, Fangfang, Wang, Rubing, Yu, Shishan, Jin, Jing, Chen, Xiaoguang
Publicado 2018

Design and Synthesis of Indoleamine 2,3-Dioxygenase 1 Inhibitors and Evaluation of Their Use as Anti-Tumor Agents

por Wen, Hui, Liu, Yuke, Wang, Shufang, Wang, Ting, Zhang, Gang, Chen, Xiaoguang, Li, Yan, Cui, Huaqing, Lai, Fangfang, Sheng, Li
Publicado 2019

Joint associations of metabolically healthy abdominal obesity and non-alcoholic fatty liver disease with prediabetes and diabetes in Chinese adults

por Zhang, Junfeng, Xu, Qiaoyan, Lai, Fangfang, Chen, Ning, Lin, Mingzhu, Liu, Yongwen, Zhang, Wei, Liu, Changqin, Wang, Shunqin, Li, Zhibin
Publicado 2021

Author correction to “YPD-30, a prodrug of YPD-29B, is an oral small-molecule inhibitor targeting PD-L1 for the treatment of human cancer” [Acta Pharmaceutica Sinica B 12 (2022) 28...

por Lai, Fangfang, Ji, Ming, Huang, Lei, Wang, Yunchen, Xue, Nina, Du, Tingting, Dong, Kai, Yao, Xiaoqing, Jin, Jing, Feng, Zhiqiang, Chen, Xiaoguang
Publicado 2023

Sphingosine-1-Phosphate Receptor Subtype 1 (S1P1) Modulator IMMH001 Regulates Adjuvant- and Collagen-Induced Arthritis

por Jin, Jing, Ji, Ming, Fu, Rong, Wang, Mingjin, Xue, Nina, Xiao, Qiong, Hu, Jingpin, Wang, Xiaojian, Lai, Fangfang, Yin, Dali, Chen, Xiaoguang
Publicado 2019

YPD-30, a prodrug of YPD-29B, is an oral small-molecule inhibitor targeting PD-L1 for the treatment of human cancer

por Lai, Fangfang, Ji, Ming, Huang, Lei, Wang, Yunchen, Xue, Nina, Du, Tingting, Dong, Kai, Yao, Xiaoqing, Jin, Jing, Feng, Zhiqiang, Chen, Xiaoguang
Publicado 2022

Associations between serum total bilirubin, obesity and type 2 diabetes

por Wei, Yuan, Liu, Chaoqun, Lai, Fangfang, Dong, Shan, Chen, Haiyan, Chen, Li, Shi, Liping, Zhu, Fengfeng, Zhang, Chuangbiao, Lv, Xiuxiu, Peng, Shuang, Hao, Guang
Publicado 2021

Association between intrahepatic triglyceride content in subjects with metabolically healthy abdominal obesity and risks of pre-diabetes plus diabetes: an observational study

por Xu, Qiaoyan, Zhang, Junfeng, Han, Haiwei, Chen, Ning, Lai, Fangfang, Liu, Yongwen, Huang, Caoxin, Lin, Mingzhu, Zhang, Wei, Wang, Shunqin, Liu, Changqin, Li, Zhibin
Publicado 2022

Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs

por Huang, Huang, Qiao, Renping, Zhao, Deyao, Zhang, Tong, Li, Youxian, Yi, Fan, Lai, Fangfang, Hong, Junmei, Ding, Xianfeng, Yang, Zhenjun, Zhang, Lihe, Du, Quan, Liang, Zicai
Publicado 2009

Chlorogenic acid inhibits glioblastoma growth through repolarizating macrophage from M2 to M1 phenotype

por Xue, Nina, Zhou, Qin, Ji, Ming, Jin, Jing, Lai, Fangfang, Chen, Ju, Zhang, Mengtian, Jia, Jing, Yang, Huarong, Zhang, Jie, Li, Wenbin, Jiang, Jiandong, Chen, Xiaoguang
Publicado 2017

A novel S1P1 modulator IMMH002 ameliorates psoriasis in multiple animal models

por Jin, Jing, Xue, Nina, Liu, Yuan, Fu, Rong, Wang, Mingjin, Ji, Ming, Lai, Fangfang, Hu, Jinping, Wang, Xiaojian, Xiao, Qiong, Zhang, Xiaoying, Yin, Dali, Bai, Liping, Chen, Xiaoguang, Rao, Shuan
Publicado 2020

S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung

por Hao, Mengyao, Fu, Rong, Tai, Jun, Tian, Zhenhuan, Yuan, Xia, Chen, Yang, Wang, Mingjin, Jiang, Huimin, Ji, Ming, Lai, Fangfang, Xue, Nina, Bai, Liping, Zhu, Yizhun, Lv, Xiaoxi, Chen, Xiaoguang, Jin, Jing
Publicado 2023

Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection

por Zhao, Xintong, Feng, Jing, Zhang, Jie, Han, Zunsheng, Hu, Yuhua, Shao, Hui-Hui, Li, Tianlei, Xia, Jie, Lei, Kangfan, Wang, Weiping, Lai, Fangfang, Lin, Yuan, Liu, Bo, Zhang, Kun, Zhang, Chi, Yang, Qingyun, Luo, Xinyu, Zhang, Hanyilan, Li, Chuang, Zhang, Wenxuan, Wu, Song
Publicado 2023