The biophysical principles underpinning muco-trapping functions of antibodies

por Schaefer, Alison, Lai, Samuel K.
Publicado 2021

Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19

por Lai, Samuel K., McSweeney, Morgan D., Pickles, Raymond J.
Publicado 2021

Altering Mucus Rheology to “Solidify” Human Mucus at the Nanoscale

por Lai, Samuel K., Wang, Ying-Ying, Cone, Richard, Wirtz, Denis, Hanes, Justin
Publicado 2009

Anaphylaxis to Pfizer/BioNTech mRNA COVID-19 Vaccine in a Patient With Clinically Confirmed PEG Allergy

por McSweeney, Morgan D., Mohan, Manoj, Commins, Scott P., Lai, Samuel K.
Publicado 2021

Physician Awareness of Immune Responses to Polyethylene Glycol‐Drug Conjugates

por McSweeney, Morgan D., Versfeld, Zina C., Carpenter, Delesha M., Lai, Samuel K.
Publicado 2018

Efficient and Highly Specific Gene Transfer Using Mutated Lentiviral Vectors Redirected with Bispecific Antibodies

por Parker, Christina L., Jacobs, Timothy M., Huckaby, Justin T., Harit, Dimple, Lai, Samuel K.
Publicado 2020

Experimental Data and PBPK Modeling Quantify Antibody Interference in PEGylated Drug Carrier Delivery

por Talkington, Anne M., Wessler, Timothy, Lai, Samuel K., Cao, Yanguang, Forest, M. Gregory
Publicado 2021

Mucoadhesive Nanoparticles May Disrupt the Protective Human Mucus Barrier by Altering Its Microstructure

por Wang, Ying-Ying, Lai, Samuel K., So, Conan, Schneider, Craig, Cone, Richard, Hanes, Justin
Publicado 2011

Bispecific binder redirected lentiviral vector enables in vivo engineering of CAR-T cells

por Huckaby, Justin T, Landoni, Elisa, Jacobs, Timothy M, Savoldo, Barbara, Dotti, Gianpietro, Lai, Samuel K
Publicado 2021

A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors

por Newby, Jay, Schiller, Jennifer L., Wessler, Timothy, Edelstein, Jasmine, Forest, M. Gregory, Lai, Samuel K.
Publicado 2017

Challenges and opportunities for antiviral monoclonal antibodies as COVID-19 therapy

por Cruz-Teran, Carlos, Tiruthani, Karthik, McSweeney, Morgan, Ma, Alice, Pickles, Raymond, Lai, Samuel K.
Publicado 2021

Common Gene Therapy Viral Vectors Do Not Efficiently Penetrate Sputum from Cystic Fibrosis Patients

por Hida, Kaoru, Lai, Samuel K., Suk, Jung Soo, Won, Sang Y., Boyle, Michael P., Hanes, Justin
Publicado 2011

The Young Innovators Program at the Eshelman Institute for Innovation: a case study examining the role of a professional pharmacy school in enhancing STEM pursuits among secondary...

por Friedman, Adam D., Melendez, Carlos R., Bush, Antonio A., Lai, Samuel K., McLaughlin, Jacqueline E.
Publicado 2017

Antibody-Mediated Immobilization of Virions in Mucus

por Jensen, Melanie A., Wang, Ying-Ying, Lai, Samuel K., Forest, M. Gregory, McKinley, Scott A.
Publicado 2019

Effect of commercial wearables and digital behaviour change resources on the physical activity of adolescents attending schools in socio-economically disadvantaged areas: the RAW-P...

por Ridgers, Nicola D., Timperio, Anna, Ball, Kylie, Lai, Samuel K., Brown, Helen, Macfarlane, Susie, Salmon, Jo
Publicado 2021

Pretreatment of Human Cervicovaginal Mucus with Pluronic F127 Enhances Nanoparticle Penetration without Compromising Mucus Barrier Properties to Herpes Simplex Virus

por Ensign, Laura M., Lai, Samuel K., Wang, Ying-Ying, Yang, Ming, Mert, Olcay, Hanes, Justin, Cone, Richard
Publicado 2014

PEGylation of nanoparticles improves their cytoplasmic transport

por Suh, Junghae, Choy, Kok-Leong, Lai, Samuel K, Suk, Jung Soo, Tang, Benjamin C, Prabhu, Sudhir, Hanes, Justin
Publicado 2007

Structure of an anti-PEG antibody reveals an open ring that captures highly flexible PEG polymers

por Huckaby, Justin T., Jacobs, Tim M., Li, Zhongbo, Perna, Robert J., Wang, Anting, Nicely, Nathan I., Lai, Samuel K.
Publicado 2020

Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post infection

por Pearson, Jason, Wessler, Timothy, Chen, Alex, Boucher, Richard C., Freeman, Ronit, Lai, Samuel K., Pickles, Raymond, Forest, M. Gregory
Publicado 2023

Modeling Neutralization Kinetics of HIV by Broadly Neutralizing Monoclonal Antibodies in Genital Secretions Coating the Cervicovaginal Mucosa

por McKinley, Scott A., Chen, Alex, Shi, Feng, Wang, Simi, Mucha, Peter J., Forest, M. Gregory, Lai, Samuel K.
Publicado 2014