Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

por Lygate, Craig A., Lake, Hannah A., McAndrew, Debra J., Neubauer, Stefan, Zervou, Sevasti
Publicado 2022

Homoarginine and creatine deficiency do not exacerbate murine ischaemic heart failure

por McAndrew, Debra J., Lake, Hannah A., Zervou, Sevasti, Schwedhelm, Edzard, Schneider, Jurgen E., Neubauer, Stefan, Lygate, Craig A.
Publicado 2022

Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro

por Zervou, Sevasti, Whittington, Hannah J., Ostrowski, Philip J., Cao, Fang, Tyler, Jack, Lake, Hannah A., Neubauer, Stefan, Lygate, Craig A.
Publicado 2017

Overexpression of mitochondrial creatine kinase preserves cardiac energetics without ameliorating murine chronic heart failure

por Cao, Fang, Maguire, Mahon L., McAndrew, Debra J., Lake, Hannah A., Neubauer, Stefan, Zervou, Sevasti, Schneider, Jürgen E., Lygate, Craig A.
Publicado 2020

Synergistic effect on cardiac energetics by targeting the creatine kinase system: in vivo application of high-resolution (31)P-CMRS in the mouse

por Maguire, Mahon L., McAndrew, Debra J., Lake, Hannah A., Ostrowski, Philip J., Zervou, Sevasti, Neubauer, Stefan, Lygate, Craig A., Schneider, Jurgen E.
Publicado 2023

A Mouse Model of Creatine Transporter Deficiency Reveals Impaired Motor Function and Muscle Energy Metabolism

por Stockebrand, Malte, Sasani, Ali, Das, Devashish, Hornig, Sönke, Hermans-Borgmeyer, Irm, Lake, Hannah A., Isbrandt, Dirk, Lygate, Craig A., Heerschap, Arend, Neu, Axel, Choe, Chi-Un
Publicado 2018

Over-expression of mitochondrial creatine kinase in the murine heart improves functional recovery and protects against injury following ischaemia–reperfusion

por Whittington, Hannah J, Ostrowski, Philip J, McAndrew, Debra J, Cao, Fang, Shaw, Andrew, Eykyn, Thomas R, Lake, Hannah A, Tyler, Jack, Schneider, Jurgen E, Neubauer, Stefan, Zervou, Sevasti, Lygate, Craig A
Publicado 2018

Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart

por Zervou, Sevasti, McAndrew, Debra J., Whittington, Hannah J., Lake, Hannah A., Park, Kyung Chan, Cha, Kuan Minn, Ostrowski, Philip J., Eykyn, Thomas R., Schneider, Jürgen E., Neubauer, Stefan, Lygate, Craig A.
Publicado 2021

Localized rest and stress human cardiac creatine kinase reaction kinetics at 3 T

por Clarke, William T., Peterzan, Mark A., Rayner, Jennifer J., Sayeed, Rana A., Petrou, Mario, Krasopoulos, George, Lake, Hannah A., Raman, Betty, Watson, William D., Cox, Pete, Hundertmark, Moritz J., Apps, Andrew P., Lygate, Craig A., Neubauer, Stefan, Rider, Oliver J., Rodgers, Christopher T.
Publicado 2019

Cardiac Energetics in Patients With Aortic Stenosis and Preserved Versus Reduced Ejection Fraction

por Peterzan, Mark A., Clarke, William T., Lygate, Craig A., Lake, Hannah A., Lau, Justin Y.C., Miller, Jack J., Johnson, Errin, Rayner, Jennifer J., Hundertmark, Moritz J., Sayeed, Rana, Petrou, Mario, Krasopoulos, George, Srivastava, Vivek, Neubauer, Stefan, Rodgers, Christopher T., Rider, Oliver J.
Publicado 2020