In silico high throughput mutagenesis and screening of signal peptides to mitigate N-terminal heterogeneity of recombinant monoclonal antibodies

por Yu, Xin, Conyne, Merlinda, Lake, Marc R., Walter, Karl A., Min, Jing
Publicado 2022

Species differences and molecular determinant of TRPA1 cold sensitivity

por Chen, Jun, Kang, Dawon, Xu, Jing, Lake, Marc, Hogan, James O., Sun, Chaohong, Walter, Karl, Yao, Betty, Kim, Donghee
Publicado 2013

Empowering therapeutic antibodies with IFN-α for cancer immunotherapy

por Guo, Jun, Xiao, Yu, Iyer, Ramesh, Lu, Xin, Lake, Marc, Ladror, Uri, Harlan, John, Samanta, Tanushree, Tomlinson, Medha, Bukofzer, Gail, Donawho, Cherrie, Shoemaker, Alex, Huang, Tzu-Hsuan
Publicado 2019

CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches

por Argiriadi, Maria A., Benatuil, Lorenzo, Dubrovska, Ievgeniia, Egan, David A., Gao, Lei, Greischar, Amy, Hardman, Jennifer, Harlan, John, Iyer, Ramesh B., Judge, Russell A., Lake, Marc, Perron, Denise C., Sadhukhan, Ramkrishna, Sielaff, Bernhard, Sousa, Silvino, Wang, Rui, McRae, Bradford L.
Publicado 2019

An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy

por Chan, Sarah, Belmar, Nicole, Ho, Sun, Rogers, Bryan, Stickler, Marcia, Graham, Michelle, Lee, Eileen, Tran, Ninian, Zhang, Dong, Gupta, Priyanka, Sho, Mien, MacDonough, Tracy, Woolley, Andrew, Kim, Han, Zhang, Hong, Liu, Wei, Zheng, Pingping, Dezso, Zoltan, Halliwill, Kyle, Ceccarelli, Michele, Rhodes, Susan, Thakur, Archana, Forsyth, Charles M., Xiong, Mengli, Tan, Siu Sze, Iyer, Ramesh, Lake, Marc, Digiammarino, Enrico, Zhou, Li, Bigelow, Lance, Longenecker, Kenton, Judge, Russell A., Liu, Cassie, Trumble, Max, Remis, Jonathan P., Fox, Melvin, Cairns, Belinda, Akamatsu, Yoshiko, Hollenbaugh, Diane, Harding, Fiona, Alvarez, Hamsell M.
Publicado 2022