Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers

por Ramos, Yolande F. M., Coutinho de Almeida, Rodrigo, Lakenberg, Nico, Suchiman, Eka, Mei, Hailiang, Kloppenburg, Margreet, Nelissen, Rob G. H. H., Meulenbelt, Ingrid
Publicado 2021

Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis

por Coutinho de Almeida, Rodrigo, Tuerlings, Margo, Ramos, Yolande, Den Hollander, Wouter, Suchiman, Eka, Lakenberg, Nico, Nelissen, Rob G H H, Mei, Hailiang, Meulenbelt, Ingrid
Publicado 2022

Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis

por Houtman, Evelyn, van Hoolwerff, Marcella, Lakenberg, Nico, Suchiman, Eka H. D., van der Linden-van der Zwaag, Enrike, Nelissen, Rob G. H. H., Ramos, Yolande F. M., Meulenbelt, Ingrid
Publicado 2021

Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice

por Bomer, Nils, Cornelis, Frederique M. F., Ramos, Yolande F. M., den Hollander, Wouter, Lakenberg, Nico, van der Breggen, Ruud, Storms, Lies, Slagboom, P. Eline, Lories, Rik J. U., Meulenbelt, Ingrid
Publicado 2016

Elucidating Epigenetic Regulation by Identifying Functional cis‐Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage

por van Hoolwerff, Marcella, Metselaar, Paula I., Tuerlings, Margo, Suchiman, H. Eka D., Lakenberg, Nico, Ramos, Yolande F.M., Cats, Davy, Nelissen, Rob G.H.H., Broekhuis, Demiën, Mei, Hailiang, de Almeida, Rodrigo Coutinho, Meulenbelt, Ingrid
Publicado 2020

Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration

por Coutinho de Almeida, Rodrigo, Mahfouz, Ahmed, Mei, Hailiang, Houtman, Evelyn, den Hollander, Wouter, Soul, Jamie, Suchiman, Eka, Lakenberg, Nico, Meessen, Jennifer, Huetink, Kasper, Nelissen, Rob G H H, Ramos, Yolande F M, Reinders, Marcel, Meulenbelt, Ingrid
Publicado 2020

Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis

por Tuerlings, Margo, van Hoolwerff, Marcella, van Bokkum, Jessica M, Suchiman, H Eka D, Lakenberg, Nico, Broekhuis, Demiën, Nelissen, Rob G H H, Ramos, Yolande F M, Mei, Hailiang, Cats, Davy, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2021

Genes Involved in the Osteoarthritis Process Identified through Genome Wide Expression Analysis in Articular Cartilage; the RAAK Study

por Ramos, Yolande F. M., den Hollander, Wouter, Bovée, Judith V. M. G., Bomer, Nils, van der Breggen, Ruud, Lakenberg, Nico, Keurentjes, J. Christiaan, Goeman, Jelle J., Slagboom, P. Eline, Nelissen, Rob G. H. H., Bos, Steffan D., Meulenbelt, Ingrid
Publicado 2014

Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes

por Houtman, Evelyn, Tuerlings, Margo, Suchiman, H Eka D, Lakenberg, Nico, Cornelis, Frederique M F, Mei, Hailiang, Broekhuis, Demiën, Nelissen, Rob G H H, Coutinho de Almeida, Rodrigo, Ramos, Yolande F M, Lories, Rik J, Cruz, Luis J, Meulenbelt, Ingrid
Publicado 2022

RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment T...

por Tuerlings, Margo, van Hoolwerff, Marcella, Houtman, Evelyn, Suchiman, Eka H. E. D., Lakenberg, Nico, Mei, Hailiang, van der Linden, Enrike H. M. J., Nelissen, Rob R. G. H. H., Ramos, Yolande Y. F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2021

RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage

por Coutinho de Almeida, Rodrigo, Ramos, Yolande F M, Mahfouz, Ahmed, den Hollander, Wouter, Lakenberg, Nico, Houtman, Evelyn, van Hoolwerff, Marcella, Suchiman, H Eka D, Rodríguez Ruiz, Alejandro, Slagboom, P Eline, Mei, Hailiang, Kiełbasa, Szymon M, Nelissen, Rob G H H, Reinders, Marcel, Meulenbelt, Ingrid
Publicado 2019

Annotating Transcriptional Effects of Genetic Variants in Disease‐Relevant Tissue: Transcriptome‐Wide Allelic Imbalance in Osteoarthritic Cartilage

por den Hollander, Wouter, Pulyakhina, Irina, Boer, Cindy, Bomer, Nils, van der Breggen, Ruud, Arindrarto, Wibowo, Couthino de Almeida, Rodrigo, Lakenberg, Nico, Sentner, Thom, Laros, Jeroen F. J., ‘t Hoen, Peter A. C., Slagboom, Eline P. E., Nelissen, Rob G. H. H., van Meurs, Joyce, Ramos, Yolande F. M., Meulenbelt, Ingrid
Publicado 2019

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis

por Bomer, Nils, den Hollander, Wouter, Ramos, Yolande F M, Bos, Steffan D, van der Breggen, Ruud, Lakenberg, Nico, Pepers, Barry A, van Eeden, Annelies E, Darvishan, Arash, Tobi, Elmar W, Duijnisveld, Bouke J, van den Akker, Erik B, Heijmans, Bastiaan T, van Roon-Mom, Willeke MC, Verbeek, Fons J, van Osch, Gerjo J V M, Nelissen, Rob G H H, Slagboom, P Eline, Meulenbelt, Ingrid
Publicado 2015

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

por Deelen, Joris, Beekman, Marian, Uh, Hae-Won, Helmer, Quinta, Kuningas, Maris, Christiansen, Lene, Kremer, Dennis, van der Breggen, Ruud, Suchiman, H Eka D, Lakenberg, Nico, van den Akker, Erik B, Passtoors, Willemijn M, Tiemeier, Henning, van Heemst, Diana, de Craen, Anton J, Rivadeneira, Fernando, de Geus, Eco J, Perola, Markus, van der Ouderaa, Frans J, Gunn, David A, Boomsma, Dorret I, Uitterlinden, André G, Christensen, Kaare, van Duijn, Cornelia M, Heijmans, Bastiaan T, Houwing-Duistermaat, Jeanine J, Westendorp, Rudi G J, Slagboom, P Eline
Publicado 2011