DNA Methylation in Skeletal Muscle Stem Cell Specification, Proliferation, and Differentiation

por Laker, Rhianna C., Ryall, James G.
Publicado 2016

Response to Comment on Laker et al. Exercise Prevents Maternal High-Fat Diet–Induced Hypermethylation of the Pgc-1α Gene and Age-Dependent Metabolic Dysfunction in the Offspring. D...

por Laker, Rhianna C., Connelly, Jessica J., Yan, Zhen
Publicado 2014

Endurance training in early life results in long‐term programming of heart mass in rats

por Wadley, Glenn D., Laker, Rhianna C., McConell, Glenn K., Wlodek, Mary E.
Publicado 2016

The Mitochondrial Permeability Transition Pore Regulator Cyclophilin D Exhibits Tissue-Specific Control of Metabolic Homeostasis

por Laker, Rhianna C., Taddeo, Evan P., Akhtar, Yasir N., Zhang, Mei, Hoehn, Kyle L., Yan, Zhen
Publicado 2016

Exercise Prevents Maternal High-Fat Diet–Induced Hypermethylation of the Pgc-1α Gene and Age-Dependent Metabolic Dysfunction in the Offspring

por Laker, Rhianna C., Lillard, Travis S., Okutsu, Mitsuharu, Zhang, Mei, Hoehn, Kyle L., Connelly, Jessica J., Yan, Zhen
Publicado 2014

Contraction influences Per2 gene expression in skeletal muscle through a calcium‐dependent pathway

por Small, Lewin, Altıntaş, Ali, Laker, Rhianna C, Ehrlich, Amy, Pattamaprapanont, Pattarawan, Villarroel, Julia, Pillon, Nicolas J, Zierath, Juleen R, Barrès, Romain
Publicado 2020

Ablation of DNA-methyltransferase 3A in skeletal muscle does not affect energy metabolism or exercise capacity

por Small, Lewin, Ingerslev, Lars R., Manitta, Eleonora, Laker, Rhianna C., Hansen, Ann N., Deeney, Brendan, Carrié, Alain, Couvert, Philippe, Barrès, Romain
Publicado 2021

Exercise leads to unfavourable cardiac remodelling and enhanced metabolic homeostasis in obese mice with cardiac and skeletal muscle autophagy deficiency

por Yan, Zhen, Kronemberger, Ana, Blomme, Jay, Call, Jarrod A., Caster, Hannah M., Pereira, Renata O., Zhao, Henan, de Melo, Vitor U., Laker, Rhianna C., Zhang, Mei, Lira, Vitor A.
Publicado 2017

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

por Laker, Rhianna C., Drake, Joshua C., Wilson, Rebecca J., Lira, Vitor A., Lewellen, Bevan M., Ryall, Karen A., Fisher, Carleigh C., Zhang, Mei, Saucerman, Jeffrey J., Goodyear, Laurie J., Kundu, Mondira, Yan, Zhen
Publicado 2017

Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis.

por Boland, Michelle L., Laker, Rhianna C., Mather, Karly, Nawrocki, Arkadiusz, Oldham, Stephanie, Boland, Brandon B., Lewis, Hilary, Conway, James, Naylor, Jacqueline, Guionaud, Silvia, Feigh, Michael, Veidal, Sanne S., Lantier, Louise, McGuinness, Owen P., Grimsby, Joseph, Rondinone, Cristina M., Jermutus, Lutz, Larsen, Martin R., Trevaskis, James L., Rhodes, Christopher J.
Publicado 2020

Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscle

por Gabriel, Brendan M., Altıntaş, Ali, Smith, Jonathon A. B., Sardon-Puig, Laura, Zhang, Xiping, Basse, Astrid L., Laker, Rhianna C., Gao, Hui, Liu, Zhengye, Dollet, Lucile, Treebak, Jonas T., Zorzano, Antonio, Huo, Zhiguang, Rydén, Mikael, Lanner, Johanna T., Esser, Karyn A., Barrès, Romain, Pillon, Nicolas J., Krook, Anna, Zierath, Juleen R.
Publicado 2021

Peptide-YY(3-36)/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergis...

por Boland, Brandon B., Laker, Rhianna C., O'Brien, Siobhan, Sitaula, Sadichha, Sermadiras, Isabelle, Nielsen, Jens Christian, Barkholt, Pernille, Roostalu, Urmas, Hecksher-Sørensen, Jacob, Sejthen, Sara Rubek, Thorbek, Ditte Dencker, Suckow, Arthur, Burmeister, Nicole, Oldham, Stephanie, Will, Sarah, Howard, Victor G., Gill, Benji M., Newton, Philip, Naylor, Jacqueline, Hornigold, David C., Austin, Jotham, Lantier, Louise, McGuinness, Owen P., Trevaskis, James L., Grimsby, Joseph S., Rhodes, Christopher J.
Publicado 2021

Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy

por Drake, Joshua C., Wilson, Rebecca J., Laker, Rhianna C., Guan, Yuntian, Spaulding, Hannah R., Nichenko, Anna S., Shen, Wenqing, Shang, Huayu, Dorn, Maya V., Huang, Kian, Zhang, Mei, Bandara, Aloka B., Brisendine, Matthew H., Kashatus, Jennifer A., Sharma, Poonam R., Young, Alexander, Gautam, Jitendra, Cao, Ruofan, Wallrabe, Horst, Chang, Paul A., Wong, Michael, Desjardins, Eric M., Hawley, Simon A., Christ, George J., Kashatus, David F., Miller, Clint L., Wolf, Matthew J., Periasamy, Ammasi, Steinberg, Gregory R., Hardie, D. Grahame, Yan, Zhen
Publicado 2021