The claudins

por Lal-Nag, Madhu, Morin, Patrice J
Publicado 2009

AI-based language models powering drug discovery and development

por Liu, Zhichao, Roberts, Ruth A., Lal-Nag, Madhu, Chen, Xi, Huang, Ruili, Tong, Weida
Publicado 2021

Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells

por Peng, Chen, Wyatt, Linda S., Glushakow-Smith, Shira G., Lal-Nag, Madhu, Weisberg, Andrea S., Moss, Bernard
Publicado 2020

Informing selection of drugs for COVID-19 treatment through adverse events analysis

por Guo, Wenjing, Pan, Bohu, Sakkiah, Sugunadevi, Ji, Zuowei, Yavas, Gokhan, Lu, Yanhui, Komatsu, Takashi E., Lal-Nag, Madhu, Tong, Weida, Patterson, Tucker A., Hong, Huixiao
Publicado 2021

Large-scale pharmacological profiling of 3D tumor models of cancer cells

por Mathews Griner, Lesley A, Zhang, Xiaohu, Guha, Rajarshi, McKnight, Crystal, Goldlust, Ian S, Lal-Nag, Madhu, Wilson, Kelli, Michael, Sam, Titus, Steve, Shinn, Paul, Thomas, Craig J, Ferrer, Marc
Publicado 2016

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity

por Menendez, Daniel, Anand, Jay R., Murphy, Carri C., Bell, Whitney J., Fu, Jiaqi, Slepushkina, Nadia, Buehler, Eugen, Martin, Scott E., Lal-Nag, Madhu, Nitiss, John L., Resnick, Michael A.
Publicado 2022

Erratum: Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy

por Kenny, Hilary A., Lal-Nag, Madhu, White, Erin A., Shen, Min, Chiang, Chun-Yi, Mitra, Anirban K., Zhang, Yilin, Curtis, Marion, Schryver, Elizabeth M., Bettis, Sam, Jadhav, Ajit, Boxer, Matthew B., Li, Zhuyin, Ferrer, Marc, Lengyel, Ernst
Publicado 2016

AI-powered drug repurposing for developing COVID-19 treatments

por Liu, Zhichao, Chen, Xi, Carter, Wendy, Moruf, Alicia, Komatsu, Takashi E., Pahwa, Sonia, Chan-Tack, Kirk, Snyder, Kevin, Petrick, Nicholas, Cha, Kenny, Lal-Nag, Madhu, Hatim, Qais, Thakkar, Shraddha, Lin, Yu, Huang, Ruili, Wang, Dong, Patterson, Tucker A., Tong, Weida
Publicado 2022

A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics

por Tschapalda, Kirsten, Zhang, Ya-Qin, Liu, Li, Golovnina, Kseniya, Schlemper, Thomas, Eichmann, Thomas O., Lal-Nag, Madhu, Sreenivasan, Urmila, McLenithan, John, Ziegler, Slava, Sztalryd, Carole, Lass, Achim, Auld, Douglas, Oliver, Brian, Waldmann, Herbert, Li, Zhuyin, Shen, Min, Boxer, Matthew B., Beller, Mathias
Publicado 2016

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity

por Yang, Shyh-Ming, Martinez, Natalia J., Yasgar, Adam, Danchik, Carina, Johansson, Catrine, Wang, Yuhong, Baljinnyam, Bolormaa, Wang, Amy Q., Xu, Xin, Shah, Pranav, Cheff, Dorian, Wang, Xinran S., Roth, Jacob, Lal-Nag, Madhu, Dunford, James E., Oppermann, Udo, Vasiliou, Vasilis, Simeonov, Anton, Jadhav, Ajit, Maloney, David J.
Publicado 2018

An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication

por Song, Guang, Lee, Emily M., Pan, Jianbo, Xu, Miao, Rho, Hee-Sool, Cheng, Yichen, Whitt, Nadia, Yang, Shu, Kouznetsova, Jennifer, Klumpp-Thomas, Carleen, Michael, Samuel G., Moore, Cedric, Yoon, Ki-Jun, Christian, Kimberly M., Simeonov, Anton, Huang, Wenwei, Xia, Menghang, Huang, Ruili, Lal-Nag, Madhu, Tang, Hengli, Zheng, Wei, Qian, Jiang, Song, Hongjun, Ming, Guo-li, Zhu, Heng
Publicado 2021

Corrigendum to “An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication” [Genomics Proteomics Bioinformatics19 (...

por Song, Guang, Lee, Emily M., Pan, Jianbo, Xu, Miao, Rho, Hee-Sool, Cheng, Yichen, Whitt, Nadia, Yang, Shu, Kouznetsova, Jennifer, Klumpp-Thomas, Carleen, Michael, Samuel G., Moore, Cedric, Yoon, Ki-Jun, Christian, Kimberly M., Simeonov, Anton, Huang, Wenwei, Xia, Menghang, Huang, Ruili, Lal-Nag, Madhu, Tang, Hengli, Zheng, Wei, Qian, Jiang, Song, Hongjun, Ming, Guo-li, Zhu, Heng
Publicado 2022

Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium

por Laurent, Louise C., Abdel-Mageed, Asim B., Adelson, P. David, Arango, Jorge, Balaj, Leonora, Breakefield, Xandra, Carlson, Elizabeth, Carter, Bob S., Majem, Blanca, Chen, Clark C., Cocucci, Emanuele, Danielson, Kirsty, Courtright, Amanda, Das, Saumya, Elmageed, Zakaria Y. Abd, Enderle, Daniel, Ezrin, Alan, Ferrer, Marc, Freedman, Jane, Galas, David, Gandhi, Roopali, Huentelman, Matthew J., Van Keuren-Jensen, Kendall, Kalani, Yashar, Kim, Yong, Krichevsky, Anna M., Lai, Charles, Lal-Nag, Madhu, Laurent, Clara D., Leonardo, Trevor, Li, Feng, Malenica, Ivana, Mondal, Debasis, Nejad, Parham, Patel, Tushar, Raffai, Robert L., Rubio, Renee, Skog, Johan, Spetzler, Robert, Sun, Jie, Tanriverdi, Kahraman, Vickers, Kasey, Wang, Liang, Wang, Yaoyu, Wei, Zhiyun, Weiner, Howard L., Wong, David, Yan, Irene K., Yeri, Ashish, Gould, Stephen
Publicado 2015

Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery

por Coussens, Nathan P., Sittampalam, G. Sitta, Guha, Rajarshi, Brimacombe, Kyle, Grossman, Abigail, Chung, Thomas D. Y., Weidner, Jeffrey R., Riss, Terry, Trask, O. Joseph, Auld, Douglas, Dahlin, Jayme L., Devanaryan, Viswanath, Foley, Timothy L., McGee, James, Kahl, Steven D., Kales, Stephen C., Arkin, Michelle, Baell, Jonathan, Bejcek, Bruce, Gal‐Edd, Neely, Glicksman, Marcie, Haas, Joseph V., Iversen, Philip W., Hoeppner, Marilu, Lathrop, Stacy, Sayers, Eric, Liu, Hanguan, Trawick, Bart, McVey, Julie, Lemmon, Vance P., Li, Zhuyin, McManus, Owen, Minor, Lisa, Napper, Andrew, Wildey, Mary Jo, Pacifici, Robert, Chin, William W., Xia, Menghang, Xu, Xin, Lal‐Nag, Madhu, Hall, Matthew D., Michael, Sam, Inglese, James, Simeonov, Anton, Austin, Christopher P.
Publicado 2018