Applications of transcriptomics in support of drug development for osteoarthritis

por Kaplon, Hélène, Luo, Yufei, De Ceuninck, Frédéric, Lalande, Agnès, Courtade-Gaiani, Sophie, Laigle, Laurence, Moingeon, Philippe
Publicado 2021

A simple inclusion criteria combination increases the rate of cartilage loss in patients with knee osteoarthritis

por Imbert, Olivier, Chimits, Damien, Guedj, Mickaël, Lorieau, Freddy, Bernard, Katy, Lalande, Agnès, Wirth, Wolfgang, Eckstein, Felix, Pueyo, Maria
Publicado 2021

Safety, Pharmacokinetics, and Pharmacodynamics of the ADAMTS‐5 Inhibitor GLPG1972/S201086 in Healthy Volunteers and Participants With Osteoarthritis of the Knee or Hip

por van der Aar, Ellen, Deckx, Henri, Dupont, Sonia, Fieuw, Ann, Delage, Stephane, Larsson, Staffan, Struglics, André, Lohmander, L. Stefan, Lalande, Agnes, Leroux, Emilie, Amantini, David, Passier, Paul
Publicado 2021

A deep learning method for predicting knee osteoarthritis radiographic progression from MRI

por Schiratti, Jean-Baptiste, Dubois, Rémy, Herent, Paul, Cahané, David, Dachary, Jocelyn, Clozel, Thomas, Wainrib, Gilles, Keime-Guibert, Florence, Lalande, Agnes, Pueyo, Maria, Guillier, Romain, Gabarroca, Christine, Moingeon, Philippe
Publicado 2021

Neuropathic pain in the IMI-APPROACH knee osteoarthritis cohort: prevalence and phenotyping

por van Helvoort, Eefje Martine, Welsing, Paco M J, Jansen, Mylène P, Gielis, Willem Paul, Loef, Marieke, Kloppenburg, Margreet, Blanco, Francisco, Haugen, Ida K, Berenbaum, Francis, Bay-Jensen, Anne-C, Ladel, Christoph, Lalande, Agnes, Larkin, Jonathan, Loughlin, John, Mobasheri, Ali, Weinans, Harrie, Lafeber, Floris, Eijkelkamp, Niels, Mastbergen, Simon
Publicado 2021

Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort

por Roemer, Frank W., Jansen, Mylène, Marijnissen, Anne C. A., Guermazi, Ali, Heiss, Rafael, Maschek, Susanne, Lalande, Agnes, Blanco, Francisco J., Berenbaum, Francis, van de Stadt, Lotte A., Kloppenburg, Margreet, Haugen, Ida K., Ladel, Christoph H., Bacardit, Jaume, Wisser, Anna, Eckstein, Felix, Lafeber, Floris P. J. G., Weinans, Harrie H., Wirth, Wolfgang
Publicado 2022

Predicted and actual 2-year structural and pain progression in the IMI-APPROACH knee osteoarthritis cohort

por van Helvoort, Eefje M, Jansen, Mylène P, Marijnissen, Anne C A, Kloppenburg, Margreet, Blanco, Francisco J, Haugen, Ida K, Berenbaum, Francis, Bay-Jensen, Anne-Christine C, Ladel, Christoph, Lalande, Agnes, Larkin, Jonathan, Loughlin, John, Mobasheri, Ali, Weinans, Harrie H, Widera, Pawel, Bacardit, Jaume, Welsing, Paco M J, Lafeber, Floris P J G
Publicado 2022

Development and validation of a machine learning-supported strategy of patient selection for osteoarthritis clinical trials: the IMI-APPROACH study

por Widera, Paweł, Welsing, Paco M.J., Danso, Samuel O., Peelen, Sjaak, Kloppenburg, Margreet, Loef, Marieke, Marijnissen, Anne C., van Helvoort, Eefje M., Blanco, Francisco J., Magalhães, Joana, Berenbaum, Francis, Haugen, Ida K., Bay-Jensen, Anne-Christine, Mobasheri, Ali, Ladel, Christoph, Loughlin, John, Lafeber, Floris P.J.G., Lalande, Agnès, Larkin, Jonathan, Weinans, Harrie, Bacardit, Jaume
Publicado 2023

Cohort profile: The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and predic...

por van Helvoort, Eefje M, van Spil, Willem E, Jansen, Mylène P, Welsing, Paco M J, Kloppenburg, Margreet, Loef, Marieke, Blanco, Francisco J, Haugen, Ida K, Berenbaum, Francis, Bacardit, Jaume, Ladel, Christoph H, Loughlin, John, Bay-Jensen, Anne C, Mobasheri, Ali, Larkin, Jonathan, Boere, Janneke, Weinans, Harrie H, Lalande, Agnes, Marijnissen, Anne C A, Lafeber, Floris P J G
Publicado 2020