Cystatin M/E (Cystatin 6): A Janus-Faced Cysteine Protease Inhibitor with Both Tumor-Suppressing and Tumor-Promoting Functions

por Lalmanach, Gilles, Kasabova-Arjomand, Mariana, Lecaille, Fabien, Saidi, Ahlame
Publicado 2021

The Interplay of Glycosaminoglycans and Cysteine Cathepsins in Mucopolysaccharidosis

por David, Alexis, Chazeirat, Thibault, Saidi, Ahlame, Lalmanach, Gilles, Lecaille, Fabien
Publicado 2023

Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants

por Lalmanach, Gilles, Saidi, Ahlame, Bigot, Paul, Chazeirat, Thibault, Lecaille, Fabien, Wartenberg, Mylène
Publicado 2020

Eimeripain, a Cathepsin B-Like Cysteine Protease, Expressed throughout Sporulation of the Apicomplexan Parasite Eimeria tenella

por Rieux, Anaïs, Gras, Simon, Lecaille, Fabien, Niepceron, Alisson, Katrib, Marilyn, Smith, Nicholas C., Lalmanach, Gilles, Brossier, Fabien
Publicado 2012

Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis

por Kasabova, Mariana, Villeret, Bérengère, Gombault, Aurélie, Lecaille, Fabien, Reinheckel, Thomas, Marchand-Adam, Sylvain, Couillin, Isabelle, Lalmanach, Gilles
Publicado 2016

Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L

por Saidi, Ahlame, Kasabova, Mariana, Vanderlynden, Lise, Wartenberg, Mylène, Kara-Ali, Ghania Hounana, Marc, Daniel, Lecaille, Fabien, Lalmanach, Gilles
Publicado 2019

Cleavage of Occludin by Cigarette Smoke-Elicited Cathepsin S Increases Permeability of Lung Epithelial Cells

por Bigot, Paul, Chesseron, Simon, Saidi, Ahlame, Sizaret, Damien, Parent, Christelle, Petit-Courty, Agnès, Courty, Yves, Lecaille, Fabien, Lalmanach, Gilles
Publicado 2022

Human Cysteine Cathepsins Are Not Reliable Markers of Infection by Pseudomonas aeruginosa in Cystic Fibrosis

por Naudin, Clément, Joulin-Giet, Alix, Couetdic, Gérard, Plésiat, Patrick, Szymanska, Aneta, Gorna, Emilia, Gauthier, Francis, Kasprzykowski, Franciszek, Lecaille, Fabien, Lalmanach, Gilles
Publicado 2011

Cleavage of Nidogen-1 by Cathepsin S Impairs Its Binding to Basement Membrane Partners

por Sage, Juliette, Leblanc-Noblesse, Emmanuelle, Nizard, Carine, Sasaki, Takako, Schnebert, Sylvianne, Perrier, Eric, Kurfurst, Robin, Brömme, Dieter, Lalmanach, Gilles, Lecaille, Fabien
Publicado 2012

Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis

por Lamort, Anne-Sophie, Hamon, Yveline, Czaplewski, Cezary, Gieldon, Artur, Seren, Seda, Coquet, Laurent, Lecaille, Fabien, Lesner, Adam, Lalmanach, Gilles, Gauthier, Francis, Jenne, Dieter, Korkmaz, Brice
Publicado 2019

The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity

por Bailleul, Geoffrey, Kravtzoff, Amanda, Joulin-Giet, Alix, Lecaille, Fabien, Labas, Valérie, Meudal, Hervé, Loth, Karine, Teixeira-Gomes, Ana-Paula, Gilbert, Florence B., Coquet, Laurent, Jouenne, Thierry, Brömme, Dieter, Schouler, Catherine, Landon, Céline, Lalmanach, Gilles, Lalmanach, Anne-Christine
Publicado 2016

GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition

por Bestion, Eloïne, Jilkova, Zuzana Macek, Mège, Jean-Louis, Novello, Marie, Kurma, Keerthi, Pour, Seyedeh Tayebeh Ahmad, Lalmanach, Gilles, Vanderlynden, Lise, Fizanne, Lionel, Bassissi, Firas, Rachid, Madani, Tracz, Jennifer, Boursier, Jérôme, Courcambeck, Jérôme, Serdjebi, Cindy, Ansaldi, Christelle, Decaens, Thomas, Halfon, Philippe, Brun, Sonia
Publicado 2020

GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions

por Brun, Sonia, Bestion, Eloïne, Raymond, Eric, Bassissi, Firas, Jilkova, Zuzana Macek, Mezouar, Soraya, Rachid, Madani, Novello, Marie, Tracz, Jennifer, Hamaï, Ahmed, Lalmanach, Gilles, Vanderlynden, Lise, Legouffe, Raphael, Stauber, Jonathan, Schubert, Thomas, Plach, Maximilian G., Courcambeck, Jérôme, Drouot, Cyrille, Jacquemot, Guillaume, Serdjebi, Cindy, Roth, Gael, Baudoin, Jean-Pierre, Ansaldi, Christelle, Decaens, Thomas, Halfon, Philippe
Publicado 2021