DEFLATE Compression Algorithm Corrects for Overestimation of Phylogenetic Diversity by Grantham Approach to Single-Nucleotide Polymorphism Classification

por Schlosberg, Arran, Lam, Brian Y. H., Yeo, Giles S. H., Clifton-Bligh, Roderick J.
Publicado 2014

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

por Adriaenssens, Alice E., Svendsen, Berit, Lam, Brian Y. H., Yeo, Giles S. H., Holst, Jens J., Reimann, Frank, Gribble, Fiona M.
Publicado 2016

Human embryonic genome activation initiates at the one-cell stage

por Asami, Maki, Lam, Brian Y.H., Ma, Marcella K., Rainbow, Kara, Braun, Stefanie, VerMilyea, Matthew D., Yeo, Giles S.H., Perry, Anthony C.F.
Publicado 2022

Global transcriptomic analysis of the arcuate nucleus following chronic glucocorticoid treatment

por Wray, Jonathan R., Davies, Alison, Sefton, Charlotte, Allen, Tiffany-Jayne, Adamson, Antony, Chapman, Philip, Lam, Brian Y.H., Yeo, Giles S.H., Coll, Anthony P., Harno, Erika, White, Anne
Publicado 2019

A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing

por Dowsett, Georgina K.C., Lam, Brian Y.H., Tadross, John A., Cimino, Irene, Rimmington, Debra, Coll, Anthony P., Polex-Wolf, Joseph, Knudsen, Lotte Bjerre, Pyke, Charles, Yeo, Giles S.H.
Publicado 2021

Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells

por Georgescu, Teodora, Lyons, David, Doslikova, Barbora, Garcia, Ana Paula, Marston, Oliver, Burke, Luke K, Chianese, Raffaella, Lam, Brian Y H, Yeo, Giles S H, Rochford, Justin J, Garfield, Alastair S, Heisler, Lora K
Publicado 2020

Combination of Ginsenosides Rb2 and Rg3 Promotes Angiogenic Phenotype of Human Endothelial Cells via PI3K/Akt and MAPK/ERK Pathways

por Choi, Ran Joo, Mohamad Zobir, Siti Zuraidah, Alexander-Dann, Ben, Sharma, Nitin, Ma, Marcella K.L., Lam, Brian Y.H., Yeo, Giles S.H., Zhang, Weidong, Fan, Tai-Ping, Bender, Andreas
Publicado 2021

Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome

por Polex-Wolf, Joseph, Lam, Brian Y.H., Larder, Rachel, Tadross, John, Rimmington, Debra, Bosch, Fàtima, Cenzano, Verónica Jiménez, Ayuso, Eduard, Ma, Marcella K.L., Rainbow, Kara, Coll, Anthony P., O’Rahilly, Stephen, Yeo, Giles S.H.
Publicado 2018

Glucose in the hypothalamic paraventricular nucleus regulates GLP-1 release

por Ma, Yue, Ratnasabapathy, Risheka, De Backer, Ivan, Izzi-Engbeaya, Chioma, Nguyen-Tu, Marie-Sophie, Cuenco, Joyceline, Jones, Ben, John, Christopher D., Lam, Brian Y.H., Rutter, Guy A., Yeo, Giles S.H., Dhillo, Waljit S., Gardiner, James
Publicado 2020

Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells

por Yang, Ming, Darwish, Tamana, Larraufie, Pierre, Rimmington, Debra, Cimino, Irene, Goldspink, Deborah A., Jenkins, Benjamin, Koulman, Albert, Brighton, Cheryl A., Ma, Marcella, Lam, Brian Y. H., Coll, Anthony P., O’Rahilly, Stephen, Reimann, Frank, Gribble, Fiona M.
Publicado 2021

Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing

por Lam, Brian Y.H., Cimino, Irene, Polex-Wolf, Joseph, Nicole Kohnke, Sara, Rimmington, Debra, Iyemere, Valentine, Heeley, Nicholas, Cossetti, Chiara, Schulte, Reiner, Saraiva, Luis R., Logan, Darren W., Blouet, Clemence, O'Rahilly, Stephen, Coll, Anthony P., Yeo, Giles S.H.
Publicado 2017

Impaired Autophagy in CD11b(+) Dendritic Cells Expands CD4(+) Regulatory T Cells and Limits Atherosclerosis in Mice

por Clement, Marc, Raffort, Juliette, Lareyre, Fabien, Tsiantoulas, Dimitrios, Newland, Stephen, Lu, Yuning, Masters, Leanne, Harrison, James, Saveljeva, Svetlana, Ma, Marcella K.L., Ozsvar-Kozma, Maria, Lam, Brian Y.H., Yeo, Giles S.H., Binder, Christoph J., Kaser, Arthur, Mallat, Ziad
Publicado 2019

Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function

por Hammerle, Constanze M., Sandovici, Ionel, Brierley, Gemma V., Smith, Nicola M., Zimmer, Warren E., Zvetkova, Ilona, Prosser, Haydn M., Sekita, Yoichi, Lam, Brian Y. H., Ma, Marcella, Cooper, Wendy N., Vidal-Puig, Antonio, Ozanne, Susan E., Medina-Gómez, Gema, Constância, Miguel
Publicado 2020

Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice

por Ramos-Pittol, Jose M., Fernandes-Freitas, Isabel, Milona, Alexandra, Manchishi, Stephen M., Rainbow, Kara, Lam, Brian Y. H., Tadross, John A., Beucher, Anthony, Colledge, William H., Cebola, Inês, Murphy, Kevin G., Miguel-Aliaga, Irene, Yeo, Giles S. H., Dhillo, Waljit S., Owen, Bryn M.
Publicado 2023

Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner

por Quiñones, Mar, Hernández-Bautista, René, Beiroa, Daniel, Heras, Violeta, Torres-Leal, Francisco L., Lam, Brian Y.H., Senra, Ana, Fernø, Johan, Gómez-Valadés, Alicia García, Schwaninger, Markus, Prevot, Vincent, Yeo, Giles, Claret, Marc, López, Miguel, Diéguez, Carlos, Al-Massadi, Omar, Nogueiras, Ruben
Publicado 2021

Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression

por Wagner, Stefan, Brierley, Daniel I., Leeson-Payne, Alasdair, Jiang, Wanqing, Chianese, Raffaella, Lam, Brian Y.H., Dowsett, Georgina K.C., Cristiano, Claudia, Lyons, David, Reimann, Frank, Gribble, Fiona M., Martinez de Morentin, Pablo B., Yeo, Giles S.H., Trapp, Stefan, Heisler, Lora K.
Publicado 2022

Innate Lymphoid Cells Promote Recovery of Ventricular Function After Myocardial Infarction

por Yu, Xian, Newland, Stephen A., Zhao, Tian X., Lu, Yuning, Sage, Andrew S., Sun, Yanyi, Sriranjan, Rouchelle S., Ma, Marcella K.L., Lam, Brian Y.H., Nus, Meritxell, Harrison, James E., Bond, Simon J., Cheng, Xiang, Silvestre, Jean-Sébastien, Rudd, James H.F., Cheriyan, Joseph, Mallat, Ziad
Publicado 2021

Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight

por Hameed, Saira, Patterson, Michael, Dhillo, Waljit S., Rahman, Sofia A., Ma, Yue, Holton, Christopher, Gogakos, Apostolos, Yeo, Giles S.H., Lam, Brian Y.H., Polex-Wolf, Joseph, Fenske, Wiebke, Bell, Jimmy, Anastasovska, Jelena, Samarut, Jacques, Bloom, Stephen R., Bassett, J.H. Duncan, Williams, Graham R., Gardiner, James V.
Publicado 2017

SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation

por Bidault, Guillaume, Virtue, Samuel, Petkevicius, Kasparas, Jolin, Helen E., Dugourd, Aurélien, Guénantin, Anne-Claire, Leggat, Jennifer, Mahler-Araujo, Betania, Lam, Brian Y.H., Ma, Marcella K., Dale, Martin, Carobbio, Stefania, Kaser, Arthur, Fallon, Padraic G., Saez-Rodriguez, Julio, McKenzie, Andrew N.J., Vidal-Puig, Antonio
Publicado 2021

The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth

por Sandovici, Ionel, Georgopoulou, Aikaterini, Pérez-García, Vicente, Hufnagel, Antonia, López-Tello, Jorge, Lam, Brian Y.H., Schiefer, Samira N., Gaudreau, Chelsea, Santos, Fátima, Hoelle, Katharina, Yeo, Giles S.H., Burling, Keith, Reiterer, Moritz, Fowden, Abigail L., Burton, Graham J., Branco, Cristina M., Sferruzzi-Perri, Amanda N., Constância, Miguel
Publicado 2022