DSBCapture: in situ capture and direct sequencing of dsDNA breaks

por Lensing, Stefanie V., Marsico, Giovanni, Hänsel-Hertsch, Robert, Lam, Enid Y., Tannahill, David, Balasubramanian, Shankar
Publicado 2016

BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation

por Vershinin, Zlata, Feldman, Michal, Werner, Thilo, Weil, Lital Estrella, Kublanovsky, Margarita, Abaev-Schneiderman, Elina, Sklarz, Menachem, Lam, Enid Y. N., Alasad, Khawla, Picaud, Sarah, Rotblat, Barak, McAdam, Ruth A., Chalifa-Caspi, Vered, Bantscheff, Marcus, Chapman, Trevor, Lewis, Huw D., Filippakopoulos, Panagis, Dawson, Mark A., Grandi, Paola, Prinjha, Rab K., Levy, Dan
Publicado 2021

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis

por Savitski, Mikhail M., Zinn, Nico, Faelth-Savitski, Maria, Poeckel, Daniel, Gade, Stephan, Becher, Isabelle, Muelbaier, Marcel, Wagner, Anne J., Strohmer, Katrin, Werner, Thilo, Melchert, Stephanie, Petretich, Massimo, Rutkowska, Anna, Vappiani, Johanna, Franken, Holger, Steidel, Michael, Sweetman, Gavain M., Gilan, Omer, Lam, Enid Y.N., Dawson, Mark A., Prinjha, Rab K., Grandi, Paola, Bergamini, Giovanna, Bantscheff, Marcus
Publicado 2018

Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes

por Sparbier, Christina E., Gillespie, Andrea, Gomez, Juliana, Kumari, Nishi, Motazedian, Ali, Chan, Kah Lok, Bell, Charles C., Gilan, Omer, Chan, Yih-Chih, Popp, Sarah, Gough, Daniel J., Eckersley-Maslin, Melanie A., Dawson, Sarah-Jane, Lehner, Paul J., Sutherland, Kate D., Ernst, Patricia, McGeehan, Gerard M., Lam, Enid Y. N., Burr, Marian L., Dawson, Mark A.
Publicado 2023

Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death

por Garciaz, Sylvain, Guirguis, Andrew A., Müller, Sebastian, Brown, Fiona C., Chan, Yih-Chih, Motazedian, Ali, Rowe, Caitlin L., Kuzich, James A., Chan, Kah Lok, Tran, Kevin, Smith, Lorey, MacPherson, Laura, Liddicoat, Brian, Lam, Enid Y.N., Cañeque, Tatiana, Burr, Marian L., Litalien, Véronique, Pomilio, Giovanna, Poplineau, Mathilde, Duprez, Estelle, Dawson, Sarah-Jane, Ramm, Georg, Cox, Andrew G., Brown, Kristin K., Huang, David C.S., Wei, Andrew H., McArthur, Kate, Rodriguez, Raphaël, Dawson, Mark A.
Publicado 2022

An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

por Burr, Marian L., Sparbier, Christina E., Chan, Kah Lok, Chan, Yih-Chih, Kersbergen, Ariena, Lam, Enid Y.N., Azidis-Yates, Elizabeth, Vassiliadis, Dane, Bell, Charles C., Gilan, Omer, Jackson, Susan, Tan, Lavinia, Wong, Stephen Q., Hollizeck, Sebastian, Michalak, Ewa M., Siddle, Hannah V., McCabe, Michael T., Prinjha, Rab K., Guerra, Glen R., Solomon, Benjamin J., Sandhu, Shahneen, Dawson, Sarah-Jane, Beavis, Paul A., Tothill, Richard W., Cullinane, Carleen, Lehner, Paul J., Sutherland, Kate D., Dawson, Mark A.
Publicado 2019

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia

por Bell, Charles C., Fennell, Katie A., Chan, Yih-Chih, Rambow, Florian, Yeung, Miriam M., Vassiliadis, Dane, Lara, Luis, Yeh, Paul, Martelotto, Luciano G., Rogiers, Aljosja, Kremer, Brandon E., Barbash, Olena, Mohammad, Helai P., Johanson, Timothy M., Burr, Marian L., Dhar, Arindam, Karpinich, Natalie, Tian, Luyi, Tyler, Dean S., MacPherson, Laura, Shi, Junwei, Pinnawala, Nathan, Yew Fong, Chun, Papenfuss, Anthony T., Grimmond, Sean M., Dawson, Sarah-Jane, Allan, Rhys S., Kruger, Ryan G., Vakoc, Christopher R., Goode, David L., Naik, Shalin H., Gilan, Omer, Lam, Enid Y. N., Marine, Jean-Christophe, Prinjha, Rab K., Dawson, Mark A.
Publicado 2019