Senescence in human AC16 cardiac cells is associated with thymidine kinase induction and histone loss

por Kastury, Nikhitha, Hidalgo, Veronica, Pandi, Boomathi, Li, Lauren, Lam, Maggie P. Y., Lau, Edward
Publicado 2023

Cardiovascular proteomics in the era of big data: experimental and computational advances

por Lam, Maggie P. Y., Lau, Edward, Ng, Dominic C. M., Wang, Ding, Ping, Peipei
Publicado 2016

Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart

por Dostal, Vishantie, Wood, Silas D., Thomas, Cody T., Han, Yu, Lau, Edward, Lam, Maggie P. Y.
Publicado 2020

Protein prediction models support widespread post-transcriptional regulation of protein abundance by interacting partners

por Srivastava, Himangi, Lippincott, Michael J., Currie, Jordan, Canfield, Robert, Lam, Maggie P. Y., Lau, Edward
Publicado 2022

Simultaneous proteome localization and turnover analysis reveals spatiotemporal dynamics of unfolded protein responses

por Currie, Jordan, Manda, Vyshnavi, Hidalgo, Veronica, Ludwig, R. W., Lam, Maggie P. Y., Lau, Edward
Publicado 2023

Tissue Usage Preference and Intrinsically Disordered Region Remodeling of Alternative Splicing Derived Proteoforms in the Heart

por Pandi, Boomathi, Brenman, Stella, Black, Alexander, Ng, Dominic C. M., Lau, Edward, Lam, Maggie P. Y.
Publicado 2023

Co-culture with normal and senescent AC16 cardiomyocytes modulates fibrotic response in primary human ventricular fibroblasts

por Hidalgo, Veronica, Kastury, Nikhitha, Durham, Cheyanne W., Currie, Jordan, Amaya, Milton, Lam, Maggie P. Y., Lau, Edward
Publicado 2023

Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome

por Lau, Edward, Han, Yu, Williams, Damon R., Thomas, Cody T., Shrestha, Rajani, Wu, Joseph C., Lam, Maggie P.Y.
Publicado 2019

The contribution of Alu exons to the human proteome

por Lin, Lan, Jiang, Peng, Park, Juw Won, Wang, Jinkai, Lu, Zhi-xiang, Lam, Maggie P. Y., Ping, Peipei, Xing, Yi
Publicado 2016

Online coupling of reverse-phase and hydrophilic interaction liquid chromatography for protein and glycoprotein characterization

por Lam, Maggie P. Y., Siu, S. O., Lau, Edward, Mao, Xiuli, Sun, H. Z., Chiu, Philip C. N., Yeung, William S. B., Cox, David M., Chu, Ivan K.
Publicado 2010

A large dataset of protein dynamics in the mammalian heart proteome

por Lau, Edward, Cao, Quan, Ng, Dominic C.M., Bleakley, Brian J., Dincer, T. Umut, Bot, Brian M., Wang, Ding, Liem, David A., Lam, Maggie P.Y., Ge, Junbo, Ping, Peipei
Publicado 2016

Integrated omics dissection of proteome dynamics during cardiac remodeling

por Lau, Edward, Cao, Quan, Lam, Maggie P. Y., Wang, Jie, Ng, Dominic C. M., Bleakley, Brian J., Lee, Jessica M., Liem, David A., Wang, Ding, Hermjakob, Henning, Ping, Peipei
Publicado 2018

Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies

por Chour, Tony, Tian, Lei, Lau, Edward, Thomas, Dilip, Itzhaki, Ilanit, Malak, Olfat, Zhang, Joe Z., Qin, Xulei, Wardak, Mirwais, Liu, Yonggang, Chandy, Mark, Black, Katelyn E., Lam, Maggie P.Y., Neofytou, Evgenios, Wu, Joseph C.
Publicado 2021

Sex-specific responses to slow progressive pressure overload in a large animal model of HFpEF

por Eaton, Deborah M., Berretta, Remus M., Lynch, Jacqueline E., Travers, Joshua G., Pfeiffer, Ryan D., Hulke, Michelle L., Zhao, Huaqing, Hobby, Alexander R. H., Schena, Giana, Johnson, Jaslyn P., Wallner, Markus, Lau, Edward, Lam, Maggie P. Y., Woulfe, Kathleen C., Tucker, Nathan R., McKinsey, Timothy A., Wolfson, Marla R., Houser, Steven R.
Publicado 2022

HDAC6 modulates myofibril stiffness and diastolic function of the heart

por Lin, Ying-Hsi, Major, Jennifer L., Liebner, Tim, Hourani, Zaynab, Travers, Joshua G., Wennersten, Sara A., Haefner, Korey R., Cavasin, Maria A., Wilson, Cortney E., Jeong, Mark Y., Han, Yu, Gotthardt, Michael, Ferguson, Scott K., Ambardekar, Amrut V., Lam, Maggie P.Y., Choudhary, Chunaram, Granzier, Henk L., Woulfe, Kathleen C., McKinsey, Timothy A.
Publicado 2022

A high-stringency blueprint of the human proteome

por Adhikari, Subash, Nice, Edouard C., Deutsch, Eric W., Lane, Lydie, Omenn, Gilbert S., Pennington, Stephen R., Paik, Young-Ki, Overall, Christopher M., Corrales, Fernando J., Cristea, Ileana M., Van Eyk, Jennifer E., Uhlén, Mathias, Lindskog, Cecilia, Chan, Daniel W., Bairoch, Amos, Waddington, James C., Justice, Joshua L., LaBaer, Joshua, Rodriguez, Henry, He, Fuchu, Kostrzewa, Markus, Ping, Peipei, Gundry, Rebekah L., Stewart, Peter, Srivastava, Sanjeeva, Srivastava, Sudhir, Nogueira, Fabio C. S., Domont, Gilberto B., Vandenbrouck, Yves, Lam, Maggie P. Y., Wennersten, Sara, Vizcaino, Juan Antonio, Wilkins, Marc, Schwenk, Jochen M., Lundberg, Emma, Bandeira, Nuno, Marko-Varga, Gyorgy, Weintraub, Susan T., Pineau, Charles, Kusebauch, Ulrike, Moritz, Robert L., Ahn, Seong Beom, Palmblad, Magnus, Snyder, Michael P., Aebersold, Ruedi, Baker, Mark S.
Publicado 2020