Capsid-expressing DNA in AAV vectors and its elimination by use of an oversize capsid gene for vector production

por Halbert, Christine L., Metzger, Michael J., Lam, Siu-Ling, Miller, A. Dusty
Publicado 2010

Germline CRISPR/Cas9-Mediated Gene Editing Prevents Vision Loss in a Novel Mouse Model of Aniridia

por Mirjalili Mohanna, Seyedeh Zeinab, Hickmott, Jack W., Lam, Siu Ling, Chiu, Nina Y., Lengyell, Tess C., Tam, Beatrice M., Moritz, Orson L., Simpson, Elizabeth M.
Publicado 2020

ABE8e Corrects Pax6-Aniridic Variant in Humanized Mouse ESCs and via LNPs in Ex Vivo Cortical Neurons

por Adair, Bethany A., Korecki, Andrea J., Djaksigulova, Diana, Wagner, Pamela K., Chiu, Nina Y., Lam, Siu Ling, Lengyell, Tess C., Leavitt, Blair R., Simpson, Elizabeth M.
Publicado 2023

Human MiniPromoters for ocular-rAAV expression in ON bipolar, cone, corneal, endothelial, Müller glial, and PAX6 cells

por Korecki, Andrea J., Cueva-Vargas, Jorge L., Fornes, Oriol, Agostinone, Jessica, Farkas, Rachelle A., Hickmott, Jack W., Lam, Siu Ling, Mathelier, Anthony, Zhou, Michelle, Wasserman, Wyeth W., Di Polo, Adriana, Simpson, Elizabeth M.
Publicado 2021

Association between adipocyte fatty acid-binding protein with left ventricular remodelling and diastolic function in type 2 diabetes: a prospective echocardiography study

por Wu, Mei-Zhen, Lee, Chi-Ho, Chen, Yan, Yu, Shuk-Yin, Yu, Yu-Juan, Ren, Qing-Wen, Fong, Ho-Yi Carol, Wong, Pui-Fai, Tse, Hung-Fat, Lam, Siu-Ling Karen, Yiu, Kai-Hang
Publicado 2020

PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina

por Hickmott, Jack W, Chen, Chih-yu, Arenillas, David J, Korecki, Andrea J, Lam, Siu Ling, Molday, Laurie L, Bonaguro, Russell J, Zhou, Michelle, Chou, Alice Y, Mathelier, Anthony, Boye, Sanford L, Hauswirth, William W, Molday, Robert S, Wasserman, Wyeth W, Simpson, Elizabeth M
Publicado 2016

New MiniPromoter Ple345 (NEFL) Drives Strong and Specific Expression in Retinal Ganglion Cells of Mouse and Primate Retina

por Simpson, Elizabeth M., Korecki, Andrea J., Fornes, Oriol, McGill, Trevor J., Cueva-Vargas, Jorge Luis, Agostinone, Jessica, Farkas, Rachelle A., Hickmott, Jack W., Lam, Siu Ling, Mathelier, Anthony, Renner, Lauren M., Stoddard, Jonathan, Zhou, Michelle, Di Polo, Adriana, Neuringer, Martha, Wasserman, Wyeth W.
Publicado 2019

Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele

por Korecki, Andrea J., Hickmott, Jack W., Lam, Siu Ling, Dreolini, Lisa, Mathelier, Anthony, Baker, Oliver, Kuehne, Claudia, Bonaguro, Russell J., Smith, Jillian, Tan, Chin-Vern, Zhou, Michelle, Goldowitz, Daniel, Deussing, Jan M., Stewart, A. Francis, Wasserman, Wyeth W., Holt, Robert A., Simpson, Elizabeth M.
Publicado 2019

rAAV-compatible MiniPromoters for restricted expression in the brain and eye

por de Leeuw, Charles N., Korecki, Andrea J., Berry, Garrett E., Hickmott, Jack W., Lam, Siu Ling, Lengyell, Tess C., Bonaguro, Russell J., Borretta, Lisa J., Chopra, Vikramjit, Chou, Alice Y., D’Souza, Cletus A., Kaspieva, Olga, Laprise, Stéphanie, McInerny, Simone C., Portales-Casamar, Elodie, Swanson-Newman, Magdalena I., Wong, Kaelan, Yang, George S., Zhou, Michelle, Jones, Steven J. M., Holt, Robert A., Asokan, Aravind, Goldowitz, Daniel, Wasserman, Wyeth W., Simpson, Elizabeth M.
Publicado 2016