Opioids and opioid receptors; understanding pharmacological mechanisms as a key to therapeutic advances and mitigation of the misuse crisis

por Lambert, David G.
Publicado 2023

Opioids and the COVID-19 pandemic: does chronic opioid use or misuse increase clinical vulnerability?

por Lambert, David G.
Publicado 2020

Propofol and SARS-CoV-2 infection

por Hirota, Kazuyoshi, Lambert, David G.
Publicado 2020

Anaesthesia-related drugs and SARS-CoV-2 infection

por Hirota, Kazuyoshi, Lambert, David G.
Publicado 2021

Mitochondrial pharmacology turns its sights on the Ca(2+) uniporter

por Storey, Nina M, Lambert, David G
Publicado 2017

Opioids and cancer survival: are we looking in the wrong place?

por Giakomidi, Despina, Bird, Mark F., Lambert, David G.
Publicado 2022

Properdin Levels in Human Sepsis

por Stover, Cordula M., McDonald, John, Byrne, Simon, Lambert, David G., Thompson, Jonathan P.
Publicado 2015

Biased versus Partial Agonism in the Search for Safer Opioid Analgesics

por Azevedo Neto, Joaquim, Costanzini, Anna, De Giorgio, Roberto, Lambert, David G., Ruzza, Chiara, Calò, Girolamo
Publicado 2020

Soluble Vascular Adhesion Protein 1 (sVAP-1) as a biomarker for pregnancy complications: A pilot study

por Danielli, Marianna, Thomas, Roisin C., Gillies, Clare L., Lambert, David G., Khunti, Kamlesh, Tan, Bee Kang
Publicado 2023

The Nociceptin/Orphanin FQ System Is Modulated in Patients Admitted to ICU with Sepsis and after Cardiopulmonary Bypass

por Thompson, Jonathan P., Serrano-Gomez, Alcira, McDonald, John, Ladak, Nadia, Bowrey, Sarah, Lambert, David G.
Publicado 2013

Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Acti...

por Piekielna-Ciesielska, Justyna, Artali, Roberto, Azzam, Ammar A. H., Lambert, David G., Kluczyk, Alicja, Gentilucci, Luca, Janecka, Anna
Publicado 2020

The Nociceptin/Orphanin FQ Receptor Antagonist UFP-101 Reduces Microvascular Inflammation to Lipopolysaccharide In Vivo

por Brookes, Zoë L. S., Stedman, Emily N., Brown, Nicola J., Hebbes, Christopher P., Guerrini, Remo, Calo, Girolamo, Reilly, Charles S., Lambert, David G.
Publicado 2013

In vitro pharmacological characterization of a novel unbiased NOP receptor‐selective nonpeptide agonist AT‐403

por Ferrari, Federica, Malfacini, Davide, Journigan, Blair V., Bird, Mark F., Trapella, Claudio, Guerrini, Remo, Lambert, David G., Calo', Girolamo, Zaveri, Nurulain T.
Publicado 2017

Nociceptin/Orphanin FQ receptor expression in primary human umbilical vein endothelial cells is not regulated by exposure to breast cancer cell media or angiogenic stimuli

por Giakomidi, Despina, Khemiri, Sonja, Mahbuba, Wadhah, McVey, David G., Al-Janabi, Fatin, Guerrini, Remo, Calo, Girolamo, Ye, Shu, Lambert, David G.
Publicado 2022

Evaluation of [Cys(ATTO 488)(8)]Dermorphin-NH(2) as a novel tool for the study of μ-opioid peptide receptors

por Giakomidi, Despina, Bird, Mark F., McDonald, John, Marzola, Erika, Guerrini, Remo, Chanoch, Serena, Sabu, Nidhuna, Horley, Barbara, Calo, Girolamo, Lambert, David G.
Publicado 2021

In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells

por Bird, Mark F., Gallacher-Horley, Barbara, McDonald, John, McVey, David G., Al-Janabi, Fatin, Guerrini, Remo, Calo, Girolamo, Ye, Shu, Thompson, Jonathan P., Lambert, David G.
Publicado 2022

Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo)

por Bird, Mark F., Cerlesi, Maria Camilla, Brown, Mark, Malfacini, Davide, Vezzi, Vanessa, Molinari, Paola, Micheli, Laura, Mannelli, Lorenzo Di Cesare, Ghelardini, Carla, Guerrini, Remo, Calò, Girolamo, Lambert, David G.
Publicado 2016

Synthesis, Biological Activity and Molecular Docking of Chimeric Peptides Targeting Opioid and NOP Receptors

por Wtorek, Karol, Ghidini, Alessia, Gentilucci, Luca, Adamska-Bartłomiejczyk, Anna, Piekielna-Ciesielska, Justyna, Ruzza, Chiara, Sturaro, Chiara, Calò, Girolamo, Pieretti, Stefano, Kluczyk, Alicja, McDonald, John, Lambert, David G., Janecka, Anna
Publicado 2022