Endoplasmic Reticulum-Mitochondria Crosstalk and Beta-Cell Destruction in Type 1 Diabetes

por Vig, Saurabh, Lambooij, Joost M., Zaldumbide, Arnaud, Guigas, Bruno
Publicado 2021

ER stress promotes mitochondrial DNA mediated type-1 interferon response in beta-cells and interleukin-8 driven neutrophil chemotaxis

por Vig, Saurabh, Lambooij, Joost M., Dekkers, Mette C., Otto, Frank, Carlotti, Françoise, Guigas, Bruno, Zaldumbide, Arnaud
Publicado 2022

Early but Not Late Exercise Training in Mice Exacerbates Hepatic Inflammation in Developing Nonalcoholic Fatty Liver Disease

por Kovynev, Artemiy, Ying, Zhixiong, Lambooij, Joost M., van der Zande, Hendrik J.P., Guigas, Bruno, Rensen, Patrick C.N., Schönke, Milena
Publicado 2023

Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis

por Gluais‐Dagorn, Pascale, Foretz, Marc, Steinberg, Gregory R., Batchuluun, Battsetseg, Zawistowska‐Deniziak, Anna, Lambooij, Joost M., Guigas, Bruno, Carling, David, Monternier, Pierre‐Axel, Moller, David E., Bolze, Sebastien, Hallakou‐Bozec, Sophie
Publicado 2021

Dendritic cell–intrinsic LKB1-AMPK/SIK signaling controls metabolic homeostasis by limiting the hepatic Th17 response during obesity

por vanderZande, Hendrik J.P., Brombacher, Eline C., Lambooij, Joost M., Pelgrom, Leonard R., Zawistowska-Deniziak, Anna, Patente, Thiago A., Heieis, Graham A., Otto, Frank, Ozir-Fazalalikhan, Arifa, Yazdanbakhsh, Maria, Everts, Bart, Guigas, Bruno
Publicado 2023

Combined GIP receptor and GLP1 receptor agonism attenuates NAFLD in male APOE∗3-Leiden.CETP mice

por Ying, Zhixiong, van Eenige, Robin, Ge, Xiaoke, van Marwijk, Christy, Lambooij, Joost M., Guigas, Bruno, Giera, Martin, de Boer, Jan Freark, Coskun, Tamer, Qu, Hongchang, Wang, Yanan, Boon, Mariëtte R., Rensen, Patrick C.N., Kooijman, Sander
Publicado 2023

Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes

por Verberk, Sanne G. S., van der Zande, Hendrik J. P., Baardman, Jeroen, de Goede, Kyra E., Harber, Karl J., Keuning, Eelco D., Lambooij, Joost M., Otto, Frank, Zawistowska-Deniziak, Anna, de Vries, Helga E., de Winther, Menno P. J., Guigas, Bruno, Van den Bossche, Jan
Publicado 2021

Fasciola hepatica Fatty Acid Binding Protein 1 Modulates T cell Polarization by Promoting Dendritic Cell Thrombospondin-1 Secretion Without Affecting Metabolic Homeostasis in Obese...

por Zawistowska-Deniziak, Anna, Lambooij, Joost M., Kalinowska, Alicja, Patente, Thiago A., Łapiński, Maciej, van der Zande, Hendrik J. P., Basałaj, Katarzyna, de Korne, Clarize M., Chayé, Mathilde A. M., Gasan, Thomas A., Norbury, Luke J., Giera, Martin, Zaldumbide, Arnaud, Smits, Hermelijn H., Guigas, Bruno
Publicado 2022

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

por Liu, Cong, Schönke, Milena, Spoorenberg, Borah, Lambooij, Joost M, van der Zande, Hendrik JP, Zhou, Enchen, Tushuizen, Maarten E, Andreasson, Anne-Christine, Park, Andrew, Oldham, Stephanie, Uhrbom, Martin, Ahlstedt, Ingela, Ikeda, Yasuhiro, Wallenius, Kristina, Peng, Xiao-Rong, Guigas, Bruno, Boon, Mariëtte R, Wang, Yanan, Rensen, Patrick CN
Publicado 2023

The helminth glycoprotein omega‐1 improves metabolic homeostasis in obese mice through type 2 immunity‐independent inhibition of food intake

por van der Zande, Hendrik J.P., Gonzalez, Michael A., de Ruiter, Karin, Wilbers, Ruud H.P., García‐Tardón, Noemí, van Huizen, Mariska, van Noort, Kim, Pelgrom, Leonard R., Lambooij, Joost M., Zawistowska‐Deniziak, Anna, Otto, Frank, Ozir‐Fazalalikhan, Arifa, van Willigen, Danny, Welling, Mick, Poles, Jordan, van Leeuwen, Fijs, Hokke, Cornelis H., Schots, Arjen, Yazdanbakhsh, Maria, Loke, P'ng, Guigas, Bruno
Publicado 2021